Endovascular Thrombectomy for Acute Ischemic Stroke in the Filipino Population: A Clinical Experience From a Single Tertiary Center in Metro Manila, Philippines
Abstract Background and Purpose Throughout the years, stroke has remained one of the primary causes of significant morbidity and mortality. Among the therapeutic options for acute stroke management, endovascular thrombectomy intended to remove the thrombi within the intracerebral vasculature and restore adequate perfusion to the surrounding penumbra. It was recommended for eligible patients who were within 6—24 hours after the onset of neurologic symptoms. In the Philippines, only a few tertiary healthcare institutions were able to offer and perform endovascular thrombectomies. The aim was to describe the profile and discharge outcomes of endovascular thrombectomy for acute ischemic stroke at a tertiary hospital in our country. Methodology: In this retrospective study, 924 patients were admitted for acute ischemic stroke from October 2018 - August 2021. However, only 31 patients underwent mechanical thrombectomy and their records were thoroughly reviewed. Clinical and functional outcomes were measured using the National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Score (MRS), respectively. Results Among the patients included in the study, 29 subjects (93.5%) had moderate to severe disability (MRS 3-5) and 17 (54.8%) had moderate stroke (NIHSS 5-15) on admission. The identified site of the cerebrovascular thrombi was within the M1 segment of the middle cerebral artery (41.9%, n=13). The stent retriever approach was performed in 19 of the subjects (61.2%). Upon discharge, only 17 (22.6%) had favorable functional outcomes (MRS 0-2) and 6 (19.3%) resulted in mortality. Conclusion Overall, endovascular thrombectomy is a promising treatment strategy for large vessel acute ischemic stroke in a developing country.