scholarly journals Inflammatory Myofibroblastic Tumor of the Urinary Bladder with Atypical Clinical and Pathological Features: a Case Report

2021 ◽  
Author(s):  
Zhu Xingwang ◽  
Wang Yixiang ◽  
Liu Yili
Keyword(s):  
Abdominal Pain ◽  
Urinary Bladder ◽  
Clinical Features ◽  
Inflammatory Myofibroblastic Tumor ◽  
Lower Abdominal Pain ◽  
Partial Cystectomy ◽  
Ki 67 ◽  
Case Presentation ◽  
Anaplastic Lymphoma ◽  
Bladder Dome

Abstract Background: The inflammatory myofibroblastic tumor (IMT) of urinary bladder is very rare, this case and often misdiagnosed as bladder cancer. We report a patient with atypical clinical features with dysuria and lower abdominal pain. Case presentation: A 32-year-old man presented with dysuria and lower abdominal pain. Computed tomography (CT) demonstrated that a solitary non-papillary tumor was located at the wall of the bladder dome. Partial cystectomy was successfully managed. Immunohistochemically, positivity of the tumor cells for anaplastic lymphoma kinase (ALK), Actin (SM), vimentin, cytokine (CK), epithelial membrane antigen (EMA) and Ki-67. Based on the the above clinical features、histopathology and immunohistochemical, the tumor was definitively diagnosed as bladder’s IMT. After 24 months, there was no signs of recurrence and metastasis with CT and cystoscopy.Conclusion: A rare case of inflammatory myofibroblastic tumor of urinary bladder after partial cystectomy was reported. It is essential for urologists and scientists to entirely understand the characteristics of the inflammatory myofibroblastic tumor and make a better clinical guideline, to avoid over treatments.

scholarly journals Spontaneous Rupture of Urinary Bladder (SRUB) in a Young Male, Presenting as Anuria – A Case Report and Review of Literature

2014 ◽  
Vol 7 (1) ◽  
pp. 64-66
Author(s):  
Sekar Hariharasudhan ◽  
Sriram Krishnamoorthy ◽  
Sunil Shroff
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Urinary Bladder ◽  
Spontaneous Rupture ◽  
Lower Abdominal Pain ◽  
Young Male ◽  
Bladder Rupture ◽  
Emergency Laparotomy ◽  
High Morbidity ◽  
Delay In Diagnosis

Spontaneous rupture of urinary bladder is a rare condition. Most of the bladder ruptures occur in association with blunt or penetrating injuries to the lower abdomen. Most often, a vague lower abdominal pain is the mode of presentation. Rarely patients present with oliguria, anuria, uremia or urosepsis. A forty year old male, under the influence of alcohol, presented with lower abdominal pain and anuria for two days with abnormal renal function. He denied history of blunt trauma. He was diagnosed to have an intra-peritoneal rupture of urinary bladder. He underwent emergency laparotomy with repair of bladder rupture. This case report illustrates the need for a high index of clinical suspicion. Prompt diagnosis and appropriate management will help in preventing a poor clinical outcome in patients with spontaneous bladder perforation. If left untreated or if there is a considerable delay in diagnosis and intervention, it usually is associated with a high morbidity.

scholarly journals Inflammatory Myofibroblastic Tumor of the Bladder

2014 ◽  
Vol 138 (10) ◽  
pp. 1272-1277 ◽  
Author(s):  
Megan Alderman ◽  
Lakshmi P. Kunju
Keyword(s):  
Differential Diagnosis ◽  
Urinary Bladder ◽  
Inflammatory Myofibroblastic Tumor ◽  
Sarcomatoid Carcinoma ◽  
Muscularis Propria ◽  
Inflammatory Cells ◽  
Diagnostic Features ◽  
Anaplastic Lymphoma ◽  
Diagnostic Pitfall ◽  
Eosinophilic Cytoplasm

We illustrate a case of an inflammatory myofibroblastic tumor (IMT) involving the bladder in a woman with dysuria and review the literature and differential diagnosis. Inflammatory myofibroblastic tumor, also referred to as pseudosarcomatous myofibroblastic proliferation, is a rare lesion that can arise in the genitourinary system and is characterized by a fascicular arrangement of myofibroblasts with admixed inflammatory cells and slitlike vessels. Urinary bladder IMT can be a diagnostic pitfall because its histologic features (brisk mitoses, invasion into muscularis propria, and prominent nucleoli) can mimic malignancy. The differential diagnosis of urinary bladder IMT includes sarcomatoid carcinoma and leiomyosarcoma. Diagnostic features such as bland nuclear chromatin, ganglion-like cells, pale eosinophilic cytoplasm with long processes, overexpression of anaplastic lymphoma kinase (immunohistochemistry or gene rearrangement studies), and the absence of atypical mitoses help distinguish IMT from its malignant mimics. Current controversies regarding postoperative spindle cell nodule and IMT are discussed.

scholarly journals Inflammatory Myofibroblastic Tumor of the Urinary Bladder Managed by Laparoscopic Partial Cystectomy

2013 ◽  
Vol 54 (11) ◽  
pp. 797 ◽  
Author(s):  
Manas Ranjan Pradhan ◽  
Priyadarshi Ranjan ◽  
Ram Nawal Rao ◽  
Saurabh Sudhir Chipde ◽  
Krishna Pradhan ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Inflammatory Myofibroblastic Tumor ◽  
Partial Cystectomy

scholarly journals Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report

2016 ◽  
Vol 9 (2) ◽  
pp. 464-469 ◽  
Author(s):  
Toshiki Etani ◽  
Taku Naiki ◽  
Takashi Nagai ◽  
Keitaro Iida ◽  
Ryosuke Ando ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Inflammatory Myofibroblastic Tumor ◽  
Plasma Cells ◽  
Smooth Muscle Actin ◽  
Vascular Endothelial ◽  
Inflammatory Infiltration ◽  
Anaplastic Lymphoma ◽  
Resected Tumor ◽  
Muscle Invasion ◽  
Endothelial Growth Factor

An inflammatory myofibroblastic tumor (IMT) is a distinctive neoplasm composed of myofibroblastic and fibroblastic spindle cells, accompanied by inflammatory infiltration of plasma cells, lymphocytes, and eosinophils. IMTs rarely occur in the urinary bladder. It is important to distinguish this tumor from other malignant spindle cell tumors. Herein, we report a patient with an IMT showing muscle invasion, who underwent a transurethral resection of the bladder tumor and, at a later date, partial cystectomy. The resected tumor specimen revealed a proliferation of spindle-shaped cells on a background of plasma cells and lymphocytes. Immunohistochemical staining showed the tumor to be positive for anaplastic lymphoma kinase (ALK), smooth muscle actin, and vascular endothelial growth factor (VEGF). Such histopathological findings were indicative of an IMT, suggesting the use of inhibitors of ALK and VEGF as pharmacotherapy.

scholarly journals Primary hydatid cyst of the urinary bladder

2018 ◽  
pp. bcr-2018-226341 ◽  
Author(s):  
Sardar Hassan Arif ◽  
Ayad Ahmad Mohammed
Keyword(s):  
Abdominal Pain ◽  
Urinary Bladder ◽  
Hydatid Cyst ◽  
Lower Abdominal Pain ◽  
Complete Excision ◽  
Abdominal Tenderness ◽  
Superior Part ◽  
Rim Enhancement ◽  
Abdominal Examination ◽  
Primary Hydatid Cyst

A 35-year-old man presented with poorly localised lower abdominal pain for 3 months. Abdominal examination revealed lower abdominal tenderness, with normal other parts of examination. CT scan of the abdomen showed irregular multiloculated mass related to the upper part of the urinary bladder with mild rim enhancement in the postcontrast study with no areas of calcifications. During laparotomy, we found a mass attached to the superior part of the urinary bladder and arising from its wall. Complete excision was done without opening the cavity of the bladder. The mass was opened and was a hydatid cyst of the bladder containing multiple daughter cysts.

Case 9.20

2014 ◽  
pp. 458-460
Author(s):  
Christine U. Lee ◽  
James F. Glockner
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Sigmoid Colon ◽  
Signal Intensity ◽  
Lower Abdominal Pain ◽  
The Past ◽  
Bladder Dome ◽  
T2 Weighted Images

70-year-old woman with 20-lb weight loss over the past 6 months and crampy lower abdominal pain Axial fat-suppressed FSE T2-weighted images (Figure 9.20.1) and postgadolinium axial (Figure 9.20.2) and sagittal (Figure 9.20.3) 3D SPGR images demonstrate a large, heterogeneously enhancing mass in the pelvis, with markedly increased T2-signal intensity and multiple cystic regions on postcontrast images. The origin of the lesion from the sigmoid colon is difficult to discern, but it is probably best appreciated on the axial postgadolinium images. Note the invasion of the bladder dome, with a gas pocket in the anterior bladder....

Inflammatory myofibroblastic tumour of genitourinary system

2021 ◽  
Vol 71 (10) ◽  
pp. 2467
Author(s):  
Muhammad Nauman ◽  
Asad Shahzad Hasan ◽  
Gauhar Sultan ◽  
Pardeep Kumar ◽  
Mudassir Hussain ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Inflammatory Myofibroblastic Tumor ◽  
Case Series ◽  
Lower Abdominal Pain ◽  
Flank Pain ◽  
Inflammatory Myofibroblastic Tumour ◽  
Genitourinary System ◽  
Inflammatory Myofibroblastic Tumors ◽  
Management Approaches ◽  
Work Up

We describe two cases of inflammatory myofibroblastic tumor (IMT) involving genitourinary system. One patient with mass of urinary bladder presented with lower abdominal pain. Other presented with a mass involving right kidney presented with right flank pain. At time there are no specific guidelines exist for the management of inflammatory myofibroblastic tumors. In this case series we will discuss the work-up and management approaches done for each case. Continuous...

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