scholarly journals Risk Factors For Severity Of Thrombocytopenia In Full Term Infants: A Single Center Study

2020 ◽  
Author(s):  
Amira M Saber ◽  
Shereen P Aziz ◽  
Al Zahraa E Almasry ◽  
Ramadan A Mahmoud
Keyword(s):  
Neonatal Sepsis ◽  
Neonatal Intensive Care ◽  
Mode Of Delivery ◽  
Full Term ◽  
Common Finding ◽  
Inclusion Criteria ◽  
Term Infants ◽  
Common Cause ◽  
Postoperative State ◽  
Platelet Transfusions

Abstract Background Neonatal thrombocytopenia (NT) is a common finding in the neonatal intensive care unit (NICU). The main aim of this study was to assess the prevalence, rick factors and outcomes of severe NT in full term (FT) infants. Method: During the study period, all FT infants who met the inclusion criteria for NT on two occasions were included. Maternal data such as maternal age, weight, gestational age, mode of delivery, and history of systemic diseases were recorded. Furthermore, neonatal data such as gender, neonatal weight, causes/duration of admission, types of respiratory support used, blood count and outcomes for neonates admitted to the NICU were recorded. Results In total, 55 FT infants with NT met the inclusion criteria. In all, 29 (52.73%) cases had severe NT. The most common cause of NT was neonatal sepsis (20 cases, 37.03%), followed by a postoperative state (5 cases, 9.25%). Moreover, in cases of positive blood cultures, the most commonly isolated organism was Escherichia coli (6 cases, 10.90%), followed by Klebsiella (5 cases, 9.09%). Cases of severe NT, when compared to cases of mild/moderate NT associated with signs of bleeding and pulmonary/intraventricular hemorrhage (IVH) (P = 0.001), needed more platelet transfusions (P = 0.001) and had higher rates of mortality (P = 0.001). Conclusion Severe NT occurred in 52.73% of cases. The most common cause of NT was neonatal sepsis, followed by a postoperative state. Furthermore, severe NT, when compared to mild/moderate NT associated with signs of bleeding and pulmonary/IVH, needed more platelet transfusions and had increased mortality.

scholarly journals Risk Factors For Severity Of Thrombocytopenia In Full Term Infants: A Single Center Study

2020 ◽  
Author(s):  
Amira M Saber ◽  
Shereen P Aziz ◽  
Al Zahraa E Almasry ◽  
Ramadan A Mahmoud
Keyword(s):  
Lupus Erythematosus ◽  
Neonatal Sepsis ◽  
Complete Blood Count ◽  
Mode Of Delivery ◽  
Full Term ◽  
Common Finding ◽  
Inclusion Criteria ◽  
Term Infants ◽  
Postoperative State ◽  
Platelet Transfusions

Abstract Background: Neonatal thrombocytopenia (NT) (platelet count <150 x 109/L) is a common finding in the neonatal intensive care unit (NICU). The main aim of this study was to assess the prevalence, rick factors, and outcomes of severe NT in full term (FT) infants.Methods: During the study period, all FT infants who met the inclusion criteria for NT on two occasions were included. Maternal data, such as maternal age, weight, gestational age, mode of delivery, and history of systemic diseases, including diabetes mellitus, pre-eclampsia, systemic lupus erythematosus, and immune thrombocytopenic purpura, were recorded. Furthermore, neonatal data, such as gender, neonatal weight, causes/duration of admission, types of respiratory support used, complete blood count measurements, and outcomes for neonates admitted to the NICU, were recorded.Results: In total, 55 FT infants with NT met the inclusion criteria, and 29 (52.73%) cases had severe NT. The most common cause of NT was neonatal sepsis (20 cases, 36.35%), followed by a postoperative state (5 cases, 9.09%). Moreover, in cases of positive blood cultures, the most commonly isolated organism was Escherichia coli (6 cases, 10.90%), followed by Klebsiella (5 cases, 9.09%). Cases of severe NT needed more platelet transfusions (P=0.001) and had higher rates of mortality (P=0.001) when compared to cases of mild/moderate NT associated with signs of bleeding and pulmonary/intraventricular hemorrhage (IVH) (P=0.001).Conclusion: Thrombocytopenia is a frequent challenge between neonatologists. The most common causes of NT in FT infants were neonatal sepsis, followed by postoperative state. Furthermore, when severe NT compared to mild/moderate NT, associated with signs of bleeding and pulmonary/IVH, needed more platelet transfusions, and had increased mortality. Further research is needed to explain which of these complications related to severity of thrombocytopenia or were associated with the bad general condition of these patients due to their original disease.

scholarly journals Risk factors for severity of thrombocytopenia in full term infants: a single center study

2020 ◽  
Author(s):  
Amira M Saber ◽  
Shereen P Aziz ◽  
Al Zahraa E Almasry ◽  
Ramadan A Mahmoud
Keyword(s):  
Lupus Erythematosus ◽  
Neonatal Sepsis ◽  
Complete Blood Count ◽  
Mode Of Delivery ◽  
Full Term ◽  
Common Finding ◽  
Inclusion Criteria ◽  
Common Cause ◽  
Postoperative State ◽  
Platelet Transfusions

Abstract Background: Neonatal thrombocytopenia (NT) (platelet count <150 x 109/L) is a common finding in the neonatal intensive care unit (NICU). The main aim of this study was to assess the prevalence, rick factors, and outcomes of severe NT in full term (FT) infants.Methods: During the study period, all FT infants who met the inclusion criteria for NT on two occasions were included. Maternal data, such as maternal age, weight, gestational age, mode of delivery, and history of systemic diseases, including diabetes mellitus, pre-eclampsia, systemic lupus erythematosus, and immune thrombocytopenic purpura, were recorded. Furthermore, neonatal data, such as gender, neonatal weight, causes/duration of admission, types of respiratory support used, complete blood count measurements, and outcomes for neonates admitted to the NICU, were recorded.Results: In total, 55 FT infants with NT met the inclusion criteria, and 29 (52.73%) cases had severe NT. The most common cause of NT was neonatal sepsis (20 cases, 36.35%), followed by a postoperative state (5 cases, 9.09%). Moreover, in cases of positive blood cultures, the most commonly isolated organism was Escherichia coli (6 cases, 10.90%), followed by Klebsiella (5 cases, 9.09%). Cases of severe NT needed more platelet transfusions (P=0.001) and had higher rates of mortality (P=0.001) when compared to cases of mild/moderate NT associated with signs of bleeding and pulmonary/intraventricular hemorrhage (IVH) (P=0.001).Conclusion: Severe NT occurred in 52.73% of cases. The most common cause of NT was neonatal sepsis, followed by a postoperative state. Furthermore, severe NT, when compared to mild/moderate NT associated with signs of bleeding and pulmonary/IVH, needed more platelet transfusions and had increased mortality.

scholarly journals Risk factors for severity of thrombocytopenia in full term infants: a single center study

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Amira M. Saber ◽  
Shereen P. Aziz ◽  
Al Zahraa E. Almasry ◽  
Ramadan A. Mahmoud
Keyword(s):  
Risk Factors ◽  
Lupus Erythematosus ◽  
Neonatal Intensive Care ◽  
Complete Blood Count ◽  
Mode Of Delivery ◽  
Full Term ◽  
Common Finding ◽  
Inclusion Criteria ◽  
Term Infants ◽  
Platelet Transfusions

Abstract Background Neonatal thrombocytopenia (NT) (platelet count < 150 × 109/L) is a common finding in the neonatal intensive care unit (NICU). The main aim of this study was to assess the prevalence, risk factors, and outcomes of severe NT in full term (FT) infants. Methods During the study period, all FT infants who met the inclusion criteria for NT on two occasions were included. Maternal data, such as maternal age, weight, gestational age, mode of delivery, and history of systemic diseases, including diabetes mellitus, pre-eclampsia, systemic lupus erythematosus, and immune thrombocytopenic purpura, were recorded. Furthermore, neonatal data, such as gender, neonatal weight, causes/duration of admission, types of respiratory support used, complete blood count measurements, and outcomes for neonates admitted to the NICU, were recorded. Results In total, 55 FT infants with NT met the inclusion criteria, and 29 (52.73%) cases had severe NT. The most common cause of NT was neonatal sepsis (20 cases, 36.35%), followed by a postoperative state (5 cases, 9.09%). Moreover, in cases of positive blood cultures, the most commonly isolated organism was Escherichia coli (6 cases, 10.90%), followed by Klebsiella (5 cases, 9.09%). Cases of severe NT needed more platelet transfusions (P = 0.001) and had higher rates of mortality (P = 0.001) when compared to cases of mild/moderate NT associated with signs of bleeding and pulmonary/intraventricular hemorrhage (IVH) (P = 0.001). Conclusion Severe NT compared to mild/moderate NT, associated with signs of bleeding and pulmonary/IVH, needed more platelet transfusions, and had increased mortality. Further research is needed to explain which of these complications related to severity of thrombocytopenia or were associated with original disease of the babies.

scholarly journals Risk Factors For Severity Of Thrombocytopenia In Full Term Infants: A Single Center Study

2020 ◽  
Author(s):  
Amira M Saber ◽  
Shereen P Aziz ◽  
Al Zahraa E Almasry ◽  
Ramadan A Mahmoud
Keyword(s):  
Risk Factors ◽  
Lupus Erythematosus ◽  
Neonatal Intensive Care ◽  
Complete Blood Count ◽  
Mode Of Delivery ◽  
Full Term ◽  
Common Finding ◽  
Inclusion Criteria ◽  
Term Infants ◽  
Platelet Transfusions

Abstract Background: Neonatal thrombocytopenia (NT) (platelet count <150 x 109/L) is a common finding in the neonatal intensive care unit (NICU). The main aim of this study was to assess the prevalence, risk factors, and outcomes of severe NT in full term (FT) infants.Methods: During the study period, all FT infants who met the inclusion criteria for NT on two occasions were included. Maternal data, such as maternal age, weight, gestational age, mode of delivery, and history of systemic diseases, including diabetes mellitus, pre-eclampsia, systemic lupus erythematosus, and immune thrombocytopenic purpura, were recorded. Furthermore, neonatal data, such as gender, neonatal weight, causes/duration of admission, types of respiratory support used, complete blood count measurements, and outcomes for neonates admitted to the NICU, were recorded.Results: In total, 55 FT infants with NT met the inclusion criteria, and 29 (52.73%) cases had severe NT. The most common cause of NT was neonatal sepsis (20 cases, 36.35%), followed by a postoperative state (5 cases, 9.09%). Moreover, in cases of positive blood cultures, the most commonly isolated organism was Escherichia coli (6 cases, 10.90%), followed by Klebsiella (5 cases, 9.09%). Cases of severe NT needed more platelet transfusions (P=0.001) and had higher rates of mortality (P=0.001) when compared to cases of mild/moderate NT associated with signs of bleeding and pulmonary/intraventricular hemorrhage (IVH) (P=0.001).Conclusion: Severe NT compared to mild/moderate NT, associated with signs of bleeding and pulmonary/IVH, needed more platelet transfusions, and had increased mortality. Further research is needed to explain which of these complications related to severity of thrombocytopenia or were associated with original disease of the babies.

scholarly journals Risk Factors For Severity Of Thrombocytopenia In Full Term Infants: A Single Center Study

2020 ◽  
Author(s):  
Amira M Saber ◽  
Shereen P Aziz ◽  
Al Zahraa E Almasry ◽  
Ramadan A Mahmoud
Keyword(s):  
Risk Factors ◽  
Lupus Erythematosus ◽  
Neonatal Intensive Care ◽  
Complete Blood Count ◽  
Mode Of Delivery ◽  
Full Term ◽  
Common Finding ◽  
Inclusion Criteria ◽  
Term Infants ◽  
Platelet Transfusions

Abstract Background: Neonatal thrombocytopenia (NT) (platelet count <150 x 109/L) is a common finding in the neonatal intensive care unit (NICU). The main aim of this study was to assess the prevalence, risk factors, and outcomes of severe NT in full term (FT) infants.Methods: During the study period, all FT infants who met the inclusion criteria for NT on two occasions were included. Maternal data, such as maternal age, weight, gestational age, mode of delivery, and history of systemic diseases, including diabetes mellitus, pre-eclampsia, systemic lupus erythematosus, and immune thrombocytopenic purpura, were recorded. Furthermore, neonatal data, such as gender, neonatal weight, causes/duration of admission, types of respiratory support used, complete blood count measurements, and outcomes for neonates admitted to the NICU, were recorded.Results: In total, 55 FT infants with NT met the inclusion criteria, and 29 (52.73%) cases had severe NT. The most common cause of NT was neonatal sepsis (20 cases, 36.35%), followed by a postoperative state (5 cases, 9.09%). Moreover, in cases of positive blood cultures, the most commonly isolated organism was Escherichia coli (6 cases, 10.90%), followed by Klebsiella (5 cases, 9.09%). Cases of severe NT needed more platelet transfusions (P=0.001) and had higher rates of mortality (P=0.001) when compared to cases of mild/moderate NT associated with signs of bleeding and pulmonary/intraventricular hemorrhage (IVH) (P=0.001).Conclusion: Severe NT compared to mild/moderate NT, associated with signs of bleeding and pulmonary/IVH, needed more platelet transfusions, and had increased mortality. Further research is needed to explain which of these complications related to severity of thrombocytopenia or were associated with original disease of the babies.

scholarly journals Platelets in the neonatal period: developmental differences in platelet production, function, and hemostasis and the potential impact of therapies

Hematology ◽  
2012 ◽  
Vol 2012 (1) ◽  
pp. 506-511 ◽  
Author(s):  
Martha Sola-Visner
Keyword(s):  
Preterm Infants ◽  
Neonatal Intensive Care ◽  
Developmental Differences ◽  
Full Term ◽  
Term Infants ◽  
Platelet Production ◽  
Primary Hemostasis ◽  
Wall Interaction ◽  
And Function

Abstract Thrombocytopenia is a common problem among sick neonates admitted to the neonatal intensive care unit. Frequently, platelet transfusions are given to thrombocytopenic infants in an attempt to decrease the incidence or severity of hemorrhage, which is often intracranial. Whereas there is very limited evidence to guide platelet transfusion practices in this population, preterm infants in the first week of life (the highest risk period for bleeding) are nearly universally transfused at higher platelet counts than older infants or children. To a large extent, this practice has been influenced by the observation that neonatal platelets are hyporeactive in response to multiple agonists in vitro, although full-term infants exhibit normal to increased primary hemostasis. This apparently paradoxical finding is due to factors in the neonatal blood that enhance the platelet-vessel wall interaction and counteract the platelet hyporeactivity. Relatively few studies have evaluated the platelet function and primary hemostasis of preterm infants, the subset of neonates at highest risk of bleeding and those most frequently transfused. Current understanding of platelet production and function in preterm and full-term neonates, how these factors affect their response to thrombocytopenia and their primary hemostasis, and the implications of these developmental differences to transfusion medicine are reviewed herein.

Anxiety, Dysphoria, and Depression Symptoms in Mothers of Preterm Infants

2009 ◽  
Vol 104 (2) ◽  
pp. 667-679 ◽  
Author(s):  
Flávia Helena Pereira Padovani ◽  
Ana Emília Vita Carvalho ◽  
Geraldo Duarte ◽  
Francisco Eulogio Martinez ◽  
Maria Beatriz Martins Linhares
Keyword(s):  
Preterm Infants ◽  
State Anxiety ◽  
Neonatal Intensive Care ◽  
Clinical Symptoms ◽  
Clinical Status ◽  
Full Term ◽  
Depression Symptoms ◽  
Health Staff ◽  
Term Infants ◽  
Mothers Of Preterm Infants

To compare presence and severity of clinical symptoms of anxiety, dysphoria, and depression in mothers of preterm and of full-term infants and to observe changes in symptoms of mothers of preterm infants during hospitalization of the infants and after discharge, 50 mothers of preterm infants and 25 mothers of full-term infants completed the State-Trait Anxiety Inventory and the Beck Depression Inventory. The mothers with preterm infants had significantly higher clinical symptoms of State Anxiety during hospitalization than the group with full-term infants, but the clinical symptoms of anxiety in mothers of preterm infants decreased significantly after discharge. The health staff in a neonatal intensive care unit should not only be aware of infants' clinical status but also of the mothers' emotional state.

scholarly journals Research on the Application Value of Intelligent Heating Box in Newborn Nursing

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Yongzhi Lu ◽  
Guangrong Bo ◽  
Yuanyuan Hu
Keyword(s):  
Body Temperature ◽  
Neonatal Intensive Care ◽  
Statistical Significance ◽  
Intervention Group ◽  
Term Infant ◽  
Full Term ◽  
Control Group ◽  
Term Infants ◽  
Premature Babies ◽  
Heat Preservation

The aim of this study was to explore the application effect of intelligent incubator in neonatal care. We selected the period from January 1, 2018, to December 31, 2020, where there were 100 full-term and premature babies born in a hospital and transferred to the neonatal intensive care unit (NICU) within 1 hour after birth. Before the improved heat preservation, 100 full-term infants in the control group and 100 full-term infants in the intervention group of the intelligent warming box were formed into a full-term infant group for a comparative study. Statistics and comparison of the two groups of term infants and premature infants admitted to the hospital were carried out to assess body temperature and the changes in the incidence of each system. The research found that on comparison of admission body temperature between the control group and the intervention group, with the intervention group in the intelligent heating box, the incidence of hypothermia was significantly lower than that of the control group (95% vs. 37% of full-term infants; 98% vs. 49% of premature babies; there is a statistical significance ( P < 0.05 )). The intelligent heating box can reduce the fluctuation of the newborn’s body temperature, keep the internal environment of newborns stable, and provide suitable conditions for the rapid growth of newborns, suitable for clinical promotion and application.

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