scholarly journals Compound nerve action potential conduction changes in nerve trunk due to tension at various strains and strain rates

Author(s):  
Shanshan Pu ◽  
Wei Xie ◽  
Hao Wen ◽  
Junhong Xiang ◽  
Xiuju Yang ◽  
...  

Abstract This study investigated compound nerve action potential (CNAP) changes of nerve trunk subjected to stretch at various strains and strain rates. An animal model of rapid stretch injury to nerve based on traffic accidents was developed in order to study CNAP changes of nerve trunk subjected to acute stretch. 18 bullfrogs were dissected and the sciatic nerves’ trunks were obtained. The nerve trunk was stretched by 6%, 12% or 18% of its length and the tensile strain rates were 30s-1 and 50s-1 respectively. The results showed that at 6% strain and 30s-1 strain rate, the amplitude, action potential duration and conduction velocity of CNAP had a slight change. When the strain and strain rate continued to be increased, the amplitude, conduction velocity and area under the curve would be decreased while the action potential duration would be increased. At 18% strain and 50s-1 strain rate, CNAP conduction was almost completely blocked. The different strains or strain rates had a significant effect on nerve signal conduction. Under the same strain, a higher strain rate would increase the probability of nerve conduction block. These findings are of great significance to study the injury mechanism of rapid nerve stretch and to evaluate the nerve functional damage level in traffic accidents.

Author(s):  
M. F. Stevens ◽  
P. S. Follansbee

The strain rate sensitivity of a variety of materials is known to increase rapidly at strain rates exceeding ∼103 sec-1. This transition has most often in the past been attributed to a transition from thermally activated guide to viscous drag control. An important condition for imposition of dislocation drag effects is that the applied stress, σ, must be on the order of or greater than the threshold stress, which is the flow stress at OK. From Fig. 1, it can be seen for OFE Cu that the ratio of the applied stress to threshold stress remains constant even at strain rates as high as 104 sec-1 suggesting that there is not a mechanism transition but that the intrinsic strength is increasing, since the threshold strength is a mechanical measure of intrinsic strength. These measurements were made at constant strain levels of 0.2, wnich is not a guarantee of constant microstructure. The increase in threshold stress at higher strain rates is a strong indication that the microstructural evolution is a function of strain rate and that the dependence becomes stronger at high strain rates.


2019 ◽  
Vol 89 (18) ◽  
pp. 3825-3838
Author(s):  
Ahmad Abuobaid ◽  
Raja Ganesh ◽  
John W Gillespie

A dynamic loop test method for measuring strain rate-dependent fiber properties was developed. During dynamic loop testing, the fiber ends are accelerated at constant levels of 20.8, 50 and 343 m/s2. The test method is used to study Kevlar® KM2-600, which fails in axial compression due to kink band formation. The compressive failure strain and strain rate at the onset of kink band formation is calculated from the critical loop diameter ( D C), which is monitored throughout the test using a high-speed camera. The results showed that compressive failure strain increases with strain rates from quasi-static to a maximum strain rate of 116 s−1 by a factor of ∼3. Kink angles (φ) and kink band spacing ( D S) were 60 ° ± 2 ° and 16 ± 3 μm, respectively, over the strain rates tested. Rate-dependent mechanisms of compressive failure by kink band formation were discussed.


2006 ◽  
Vol 96 (6) ◽  
pp. 2963-2971 ◽  
Author(s):  
Philip M. Lang ◽  
Gila Moalem-Taylor ◽  
David J. Tracey ◽  
Hugh Bostock ◽  
Peter Grafe

Activity-dependent fluctuations in axonal excitability and changes in interspike intervals modify the conduction of trains of action potentials in unmyelinated peripheral nerve fibers. During inflammation of a nerve trunk, long stretches of axons are exposed to inflammatory mediators such as 5-hydroxytryptamine [5-HT]. In the present study, we have tested the effects of m-chlorophenylbiguanide (mCPBG), an agonist at the 5-HT(3) serotonin receptor, on activity- and potential-dependent variations in membrane threshold and conduction velocity of unmyelinated C-fiber axons of isolated rat sural nerve segments. The increase in axonal excitability during application of mCPBG was much stronger at higher frequencies of action potentials and/or during axonal membrane hyperpolarization. The effects on the postspike recovery cycle also depended on the rate of stimulation. At an action potential frequency of 1 Hz or in hyperpolarized axons, mCPBG produced a loss of superexcitability. In contrast, at 0.33 Hz, a small increase in the postspike subexcitability was observed. Similar effects on excitability changes were found when latency instead of threshold was recorded, but only at higher action potential frequencies: at 1.8 Hz, mCPBG increased conduction velocity and reduced postspike supernormality. The latter effect would increase the interspike interval if pairs of action potentials were conducted along several cm in an inflamed nerve trunk. These data indicate that activation of axonal 5-HT(3) receptors not only enhances membrane excitability but also modulates action potential trains in unmyelinated, including nociceptive, nerve fibers at high impulse rates.


2019 ◽  
Vol 2019 ◽  
pp. 1-15
Author(s):  
Peijie Liu ◽  
Yanming Quan ◽  
Guo Ding

Rail steel plays an indispensable role in the safety and stability of the railway system. Therefore, a suitable constitutive model is quite significant to understand the mechanical behavior of this material. Here, the compressive mechanical behavior of heat-treated U71Mn rail steel over a wide range of strain rates (0.001 s−1–10000 s−1) and temperatures (20°C–800°C) was systematically investigated via uniaxial quasistatic and dynamic tests. The split Hopkinson pressure bar (SHPB) apparatus was utilized to perform dynamic mechanical tests. The effects of temperature, strain, and strain rate on the dynamic compressive characteristics of U71Mn were discussed, respectively. The results indicate that the flow response of U71Mn is both temperature-sensitive and strain rate-sensitive. However, the influence of temperature on the flow response is more remarkable than that of strain rate. On the basis of the experimental data, the original and modified Johnson-Cook (JC) models of the studied material were established, respectively. Using correlation coefficient and average absolute relative error parameters, it is revealed that better agreement between the experimental and predicted stress is reached by the modified JC model, which demonstrates that the modified one can characterize the mechanical behavior of the studied material preferably.


2008 ◽  
Vol 22 (09n11) ◽  
pp. 1068-1073
Author(s):  
TOMOKAZU MASUDA ◽  
KENJI SAITO ◽  
IZUMI MORITA ◽  
SHUSHI IKEDA ◽  
KOICHI MAKII ◽  
...  

In order to evaluate dynamic deformation behaviors under high strain rates, Kobe Steel has developed and applied a Split-Hopkinson Bar (SHB) apparatus. This paper discusses the validity of the strain measurements and strain rates measured by this SHB apparatus. The strain waves that propagated in the incident and transmitted bars and the specimen are captured using a high-resolution type high-speed photography in detail. The strain wave propagated many times in the incident and transmitted bars and the specimen when the specimen was not broken. The amount of the deformation of the specimen decreases with the propagation frequency of the incident wave. On the other hand, to improve accuracy at the strain and strain rate calculated by the one-dimensional stress wave theory, Young's modulus, the longitudinal wave speed, and the density were accurately determined. It was understood that the calculation value showed the strain and strain rate captured with the high-speed photography are a good agreement. As a result, the validity of the measurement accuracy of this SHB could be shown.


2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Tao-Hsing Chen ◽  
Chih-Kai Tsai ◽  
Te-Hua Fang

The high strain shear rate behaviour of Inconel 690 alloy was investigated by using the split Hopkinson torsional bar. The shear strain rates were tested at 900 s−1, 1900 s−1, and 2600 s−1and at temperatures of −100°C, 25°C, and 300°C, respectively. It was found that the dynamic shear behaviour of Inconel 690 alloy was sensitive to strain rate and temperature. The fracture shear strain increased with increasing strain rate and temperature. In addition, the strain rate sensitivity was increased with increasing strain and strain rate but decreased with increasing temperature. Finally, the fracture surfaces were found to contain dimple-like features, and the dimple density increased with increasing strain rate and temperature.


2021 ◽  
Author(s):  
Fei Teng ◽  
Gary Menary ◽  
Savko Malinov ◽  
Shiyong Yan

In this paper, an Artificial Neural Network (ANN) is used to predict the stress-strain behavior of PET at conditions relevant to Stretch Blow Moulding i.e. Large equibiaxial deformation at elevated temperature and high strain rate. The input vectors considered are temperature, strain, and strain rate with a corresponding output parameter of stress. In the present work, a feed-forward back backpropagation algorithm was used to train the ANN. The ANN is able to approximate the relationship between stress and strain at various strain rates & temperatures to a high degree of accuracy for all conditions tested.


Sign in / Sign up

Export Citation Format

Share Document