scholarly journals Point Prevalence Survey of antimicrobial use in three hospitals in North-eastern Tanzania

2020 ◽  
Author(s):  
Pius Gerald Horumpende ◽  
Stephen Eliatosha Mshana ◽  
Elise F Mouw ◽  
Blandina Theophil Mmbaga ◽  
Jaffu Othniel Chilongola ◽  
...  
Keyword(s):  
District Hospital ◽  
Antibiotic Use ◽  
Tertiary Hospital ◽  
Point Prevalence ◽  
Prevalence Survey ◽  
Targeted Interventions ◽  
Prescription Practices ◽  
Point Prevalence Survey ◽  
Surgical Antibiotic Prophylaxis ◽  
Kilimanjaro Christian Medical Centre

Abstract Background: Antimicrobial resistance (AMR) is one of the most urgent global health threats with low-resource countries being disproportionately affected. Targeted interventions require insight in antibiotic prescription practices. A point prevalence survey (PPS) is a well-known tool to get insight in antibiotic dispensing practices in hospitals and identify areas for improvement. Here, we describe the results of a PPS performed in a tertiary, regional and district hospital in Kilimanjaro region in Tanzania. Methods: A PPS was performed in the Kilimanjaro Christian Medical Centre (KCMC; tertiary hospital), Mawenzi (regional) and St. Joseph (district) hospital in November and December 2016. Antibiotic use in all patients admitted more than 24 hours and those undergoing surgery was recorded. All clinical wards were included except the pediatrics. Data from a single ward were collected on the same day. Results: A total of 399 patients were included in the PPS: 232 patients from KCMC, 94 from Mawenzi hospital and 73 patients from St. Joseph hospital. Overall prevalence of antibiotic use was 44.0%: 38% in KCMC, 59% in Mawenzi and 63% in St. Joseph. Ceftriaxone (n=94, 29.8%), metronidazole (n=79, 23.9%) and other antibiotics belonging to the penicillin class (n=89, 28.3%) were most commonly prescribed. Antibiotics prescribed for surgical prophylaxis were continued for more than 3 days in 57% of cases.Conclusion: Our study shows a rate of broad-spectrum antibiotic use in Tanzanian hospitals and prolonged surgical antibiotic prophylaxis being a common practice. PPS is an important tool to improve future antibiotic use in Tanzania hospitals.

scholarly journals Point Prevalence survey of antimicrobial use in three hospitals in North-eastern Tanzania

2020 ◽  
Author(s):  
Pius Gerald Horumpende ◽  
Stephen Eliatosha Mshana ◽  
Elise F Mouw ◽  
Blandina Theophil Mmbaga ◽  
Jaffu Othniel Chilongola ◽  
...  
Keyword(s):  
District Hospital ◽  
Antibiotic Use ◽  
Tertiary Hospital ◽  
Point Prevalence ◽  
Prevalence Survey ◽  
Targeted Interventions ◽  
Prescription Practices ◽  
Point Prevalence Survey ◽  
Surgical Antibiotic Prophylaxis ◽  
Kilimanjaro Christian Medical Centre

Abstract Abstract Background : Antimicrobial resistance (AMR) is one of the most urgent global health threats with low-resource countries being disproportionately affected. Targeted interventions require insight in antibiotic prescription practices. A point prevalence survey (PPS) is a well-known tool to get insight in antibiotic dispensing practices in hospitals and identify areas for improvement. Here, we describe the results of a PPS performed in a tertiary, regional and district hospital in Kilimanjaro region in Tanzania. Methods: A PPS was performed in the Kilimanjaro Christian Medical Centre (KCMC; tertiary hospital), Mawenzi (regional) and St. Joseph (district) hospital in November and December 2016. Antibiotic use in all patients admitted more than 24 hours and those undergoing surgery was recorded. All clinical wards were included except the pediatrics. Data from a single ward were collected on the same day. Results : A total of 399 patients were included in the PPS: 232 patients from KCMC, 94 from Mawenzi hospital and 73 patients from St. Joseph hospital. Overall prevalence of antibiotic use was 44.0%: 38% in KCMC, 59% in Mawenzi and 63% in St. Joseph. C eftriaxone (n=94, 29.8%), metronidazole (n=79, 25.1%) and other antibiotics belonging to the penicillin class (n=89, 28.3%) were most commonly prescribed. Antibiotics prescribed for surgical prophylaxis were continued for more than 3 days in 57% of cases. Conclusion: Our study shows a rate of broad-spectrum antibiotic use in Tanzanian hospitals and prolonged surgical antibiotic prophylaxis being a common practice. PPS is an important tool to improve future antibiotic use in Tanzania hospitals.

scholarly journals Point prevalence survey of antimicrobial use in three hospitals in North-Eastern Tanzania

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Pius G. Horumpende ◽  
Stephen E. Mshana ◽  
Elise F. Mouw ◽  
Blandina T. Mmbaga ◽  
Jaffu O. Chilongola ◽  
...  
Keyword(s):  
District Hospital ◽  
Antibiotic Use ◽  
Tertiary Hospital ◽  
Point Prevalence ◽  
Prevalence Survey ◽  
Targeted Interventions ◽  
Prescription Practices ◽  
Point Prevalence Survey ◽  
Surgical Antibiotic Prophylaxis ◽  
Kilimanjaro Christian Medical Centre

Abstract Background Antimicrobial resistance (AMR) is one of the most urgent global health threats with low-resource countries being disproportionately affected. Targeted interventions require insight in antibiotic prescription practices. A point prevalence survey (PPS) is a well-known tool to get insight in antibiotic dispensing practices in hospitals and identify areas for improvement. Here, we describe the results of a PPS performed in a tertiary, regional and district hospital in Kilimanjaro region in Tanzania. Methods A PPS was performed in the Kilimanjaro Christian Medical Centre (KCMC; tertiary hospital), Mawenzi (regional) and St. Joseph (district) hospital in November and December 2016. Antibiotic use in all patients admitted more than 24 h and those undergoing surgery was recorded. All clinical wards were included except the pediatrics. Data from a single ward were collected on the same day. Results A total of 399 patients were included in the PPS: 232 patients from KCMC, 94 from Mawenzi hospital and 73 patients from St. Joseph hospital. Overall prevalence of antibiotic use was 44.0%: 38% in KCMC, 59% in Mawenzi and 63% in St. Joseph. Ceftriaxone (n = 94, 29.8%), metronidazole (n = 79, 23.9%) and other antibiotics belonging to the penicillin class (n = 89, 28.3%) were most commonly prescribed. Antibiotics prescribed for surgical prophylaxis were continued for more than 3 days in 57% of cases. Conclusion Our study shows a rate of broad-spectrum antibiotic use in Tanzanian hospitals and prolonged surgical antibiotic prophylaxis being a common practice. PPS is an important tool to improve future antibiotic use in Tanzania hospitals.

scholarly journals Using longitudinal antibiotic point prevalence survey (PPS) to drive antimicrobial stewardship programmes in a Nigerian tertiary hospital

2021 ◽  
Vol 22 (2) ◽  
pp. 284-289
Author(s):  
P. Nwajiobi-Princewill ◽  
N. Medugu ◽  
M. Gobel ◽  
A. Aigbe ◽  
A. Versporten ◽  
...  
Keyword(s):  
Antimicrobial Stewardship ◽  
Institutional Support ◽  
Patient Characteristics ◽  
Antibiotic Use ◽  
Tertiary Hospital ◽  
Point Prevalence ◽  
Policy Statement ◽  
Prevalence Survey ◽  
Middle Income ◽  
Point Prevalence Survey

Background: Antimicrobial stewardship (AMS) provides a means of tackling antimicrobial resistance (AMR). Unfortunately, in Nigeria, like in some other low-and-middle-income countries (LMICs), AMS practice has been lacklustre due to poor institutional support amongst other factors. Efforts were made to address this situation by engaging with the management of National Hospital Abuja, Nigeria, using antibiotic prescription information obtained through repeated point prevalence survey.Methodology: Two rounds of antibiotic PPS were conducted in 2015 and 2017 using the Global Point Prevalence Survey (G-PPS) format. Data were collected from all inpatients receiving antibiotics on the selected day of study, including patient characteristics, antimicrobial prescription details, laboratory results and information on a set of quality indicators. The data were uploaded to an online G-PPS application hosted at the University of Antwerp in Belgium for validation, analysis and reporting.Results: The PPS data showed that hospital-wide antibiotic use prevalence increased from 58% in 2015 to 61% in 2017. Surgical prophylaxis beyond 24 hours also increased from 88-90% in 2015 to 100% in 2017, and only minority of therapies were supported by laboratory input for diagnosis and monitoring; 22% in 2015 and 5% in 2017.Conclusion: These results were used for evidence-based engagement with the management to formally support AMS activities in the hospital. Positive outcomes were the formal reconstitution and inauguration of AMS committee in 2018 as well as the issuance of a formal policy statement by the hospital in 2020. The ease and free availability of Global PPS methodology makes it ideal in driving antimicrobial stewardship programme (ASP) in LMICs like Nigeria. Keywords: Antibiotic stewardship checklist, institutional support, point   French Title: Utilisation d'une enquête longitudinale sur la prévalence ponctuelle des antibiotiques (PPS) pour conduire des programmes de gestion des antimicrobiens dans un hôpital tertiaire nigérian Contexte: La gestion des antimicrobiens (AMS) offre un moyen de lutter contre la résistance aux antimicrobiens (RAM). Malheureusement, au Nigéria, comme dans certains autres pays à revenu faible ou intermédiaire (PRFI), la pratique de la MGS a été médiocre en raison d'un soutien institutionnel insuffisant, entre autres facteurs. Des  Longitudinal PPS for AMS programmes efforts ont été faits pour remédier à cette situation en collaborant avec la direction de l'hôpital national d'Abuja, au Nigéria, en utilisant les informations sur les prescriptions d'antibiotiques obtenues grâce à une enquête ponctuelle répétée de prévalence.Méthodologie: Deux séries d'antibiotiques PPS ont été menées en 2015 et 2017 en utilisant le format Global Point Prevalence Survey (G-PPS). Des données ont été recueillies auprès de tous les patients hospitalisés recevant des antibiotiques le jour sélectionné de l'étude, y compris les caractéristiques des patients, les détails de la prescription d'antimicrobiens, les résultats de laboratoire et les informations sur un ensemble d'indicateurs de qualité. Les données ont été téléchargées sur une application en ligne G-PPS hébergée à l'Université d'Anvers en Belgique à des fins de validation, d'analyse et rapports.Résultats: Les données PPS ont montré que la prévalence de l'utilisation d'antibiotiques à l'échelle de l'hôpital est passée de 58% en 2015 à 61% en 2017. La prophylaxie chirurgicale au-delà de 24 heures est également passée de 88 à 90% en 2015 à 100% en 2017, et seule une minorité de thérapies a été soutenue par entrée de laboratoire pour le diagnostic et la surveillance; 22% en 2015 et 5% en 2017.Conclusion: Ces résultats ont été utilisés pour un engagement fondé sur des données probantes avec la direction afin de soutenir officiellement les activités AMS à l'hôpital. Les résultats positifs ont été la reconstitution formelle et l'inauguration du comité AMS en 2018 ainsi que la publication d'une déclaration de politique formelle par l'hôpital en 2020. La facilité et la disponibilité gratuite de la méthodologie Global PPS la rend idéale pour conduire le programme de gestion des antimicrobiens (ASP) en PRFI comme le Nigéria. Mots clés: liste de contrôle pour la gestion des antibiotiques, soutien institutionnel, enquête ponctuelle de prévalence, déclaration de politique prevalence survey, policy statement  

scholarly journals A prospective antibiotic point prevalence survey in two primary referral hospitals during and after pilgrims stay in Madinah, Saudi Arabia

2020 ◽  
Vol 19 (2) ◽  
pp. 391-399
Author(s):  
Yaser M. ◽  
Ahmad K. Aljabri ◽  
Faisal N. Alsaadi ◽  
Lamiaa M. Rizk ◽  
Renad Y. Alahmadi ◽  
...  
Keyword(s):  
Quality Improvement ◽  
Antibiotic Therapy ◽  
Prevalence Rate ◽  
Antibiotic Use ◽  
Point Prevalence ◽  
Antibiotic Prescribing ◽  
Prevalence Survey ◽  
Point Prevalence Survey ◽  
Significant Difference ◽  
Referral Hospitals

Purpose: To assess current patterns of antibiotic use by carrying out two point-prevalence surveys (PPS) in Madinah after the return of hajj pilgrims from Makkah and when Madinah is free from pilgrims. Methods: In September 2016 and November 2016, a prospective PPS was conducted on two separate dates (during the hajj pilgrims stay in Madinah and after they leave). Data on antibiotics use were generated during these two periods. This involved an audit from all the departments of two referral hospitals (King Fahad Hospital (KFH) - 425 beds, and Al Ansar Hospital - 100 beds) of inpatients records. Data were collected using standard forms adapted from the European Centre for Disease Control (ECDC). Results: A total of 675 inpatients were included in PPS; among them, 332 (49.18 %) patients were receiving antibiotic therapy. In September 2016, 168 patients were treated with antibiotics, with a prevalence rate of 50.60 %, whereas, in November 2016, the prevalence rate was 49.40 %. Overall, 198 patients were identified in surgical wards, of which 132 patients (66.6 %) were receiving antibiotic therapy; 121 patients in ICU of which 70 patients (57.8 %) received antibiotics; 13 patients in other wards of which 6 (46.1 %) received antibiotic treatment; and 343 patients in medical wards of which 126 patients (36.7 %) were treated with antibiotics. There was no significant difference in prevalence of antibiotic prescribing between the two surveys (Pearson Chi-square test, p = 0.56) and with regards to patient age between the two surveys (Mann-Whitney U-test, p = 0.32). Conclusion: The results demonstrate that antibiotic use with adherence to hospital guidelines and PPS helps in identifying targets for quality improvement. Moreover, to escalate the prudent use of antibiotics in hospitals, PPS provides a useful tool. Furthermore, this survey provides a background to evaluate antibiotic use by a standardized methodology. Keywords: Point prevalence survey, Antibiotic use, Prescribing practices, Antibiotic resistance, Quality improvement, Antibiotic stewardship, Hajj, Pilgrims

scholarly journals Correlation Between Tennessee Antibiotic Use Point Prevalence Survey and NHSN AUR Module in Four Acute Care Hospitals

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S511-S511
Author(s):  
Christopher Evans ◽  
Raphaelle Beard ◽  
Zina Gugkaeva ◽  
Brooke Stayer ◽  
Candice Simpson ◽  
...  
Keyword(s):  
Acute Care ◽  
Acute Care Hospitals ◽  
Antibiotic Use ◽  
Point Prevalence ◽  
Prevalence Survey ◽  
Point Prevalence Survey

scholarly journals Variations in antibiotic use across India: multi-centre study through Global Point Prevalence survey

2019 ◽  
Vol 103 (3) ◽  
pp. 280-283 ◽  
Author(s):  
S.K. Singh ◽  
S. Sengupta ◽  
R. Antony ◽  
S. Bhattacharya ◽  
C. Mukhopadhyay ◽  
...  
Keyword(s):  
Antibiotic Use ◽  
Point Prevalence ◽  
Prevalence Survey ◽  
Multi Centre Study ◽  
Centre Study ◽  
Point Prevalence Survey

scholarly journals A Point Prevalence Survey of Antibiotic Use in 18 Hospitals in Egypt

Antibiotics ◽  
2014 ◽  
Vol 3 (3) ◽  
pp. 450-460 ◽  
Author(s):  
Maha Talaat ◽  
Tamer Saied ◽  
Amr Kandeel ◽  
Gehad El-Ata ◽  
Amani El-Kholy ◽  
...  
Keyword(s):  
Antibiotic Use ◽  
Point Prevalence ◽  
Prevalence Survey ◽  
Point Prevalence Survey

scholarly journals Antimicrobial use across six referral hospitals in Tanzania: a point prevalence survey

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e042819
Author(s):  
Jeremiah Seni ◽  
Siana G Mapunjo ◽  
Rachel Wittenauer ◽  
Richard Valimba ◽  
Andy Stergachis ◽  
...  
Keyword(s):  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Antibiotic Use ◽  
Point Prevalence ◽  
Referral Hospital ◽  
Antimicrobial Use ◽  
Prevalence Survey ◽  
Regional Referral Hospital ◽  
Point Prevalence Survey ◽  
Referral Hospitals

ObjectiveTo delineate the prevalence and factors associated with antimicrobial use across six referral hospitals in Tanzania using WHO point prevalence survey (PPS) methodology to inform hospital-specific antimicrobial stewardship programmes.DesignCross-sectional analytical study.SettingSix referral hospitals in Tanzania.ParticipantsPatients irrespective of age and gender (n=948) admitted in the six referral hospital wards before 8:00 hours on each day of the survey were included in December 2019. Using the WHO PPS methodology, data on hospitals, wards, patients, antibiotics, and indications for antibiotics were collected.Outcome measuresWe analysed the prevalence of antibiotic use by referral hospital, ward, indication and patient characteristics as the main outcomes. We also described adherence to the Tanzania Standard Treatment Guidelines (STG) and WHO’s AWaRe categorisation of antibiotics.ResultsApproximately 62.3% of inpatients were prescribed antibiotics, predominantly from the Access group of antibiotics (ceftriaxone, metronidazole or ampicillin–cloxacillin). The overall adherence of antibiotic prescriptions to the Tanzania STG was high (84.0%), with the exception of Sekou Toure Regional Referral Hospital (68.0%) and Maweni Regional Referral Hospital (57.8%). The most common indication for antibiotic prescriptions was community-acquired infections (39.8%). Children less than 2 years of age (OR 1.73, 95% CI 1.02 to 2.92, p=0.039); admission to surgical wards (OR 4.90, 95% CI 2.87 to 8.36, p <0.001); and admission to paediatric wards (OR 3.93, 95% CI 2.16 to 7.15, p <0.001) were associated with increased odds of antibiotic use. Only 2 of 591 patients were prescribed antibiotics based on culture and antimicrobial susceptibility testing results.ConclusionsEmpirical use of antibiotics is common, and the Access group of antibiotics is predominantly prescribed in children less than 2 years and patients admitted to surgical and paediatric wards. Lack of utilisation of antimicrobial susceptibility testing services in these hospitals requires urgent interventions. Routine monitoring of antibiotic use is recommended to be part of antibiotic stewardship programmes in Tanzania.

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