Inflammatory olfactory neuropathy in two patients with Covid-19

Abstract Coronavirus disease 2019 (Covid-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as a public health emergency recently, leading to fatal respiratory failure in a number of patients. The clinical manifestation of Covid-19 is manifold, cardio-respiratory symptoms and multiorgan failure being the most critical. Anosmia was reported to be an early symptom in a significant number of Covid-19 patients and is frequently the only symptom without underlying nasal congestion. Here we present neuropathological work-up of olfactory epithelium and associated olfactory nerves from two patients succumbing to Covid-19, one of which was anosmic. We show that SARS-CoV-2 infection is associated with inflammation in the olfactory epithelium and leads to axonal damage in olfactory structures of the CNS - potentially explaining anosmic symptoms.

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A Diagnosed Case of COVID-19 Treated with Homoeopathy: A Case Report

Homœopathic Links ◽

10.1055/s-0040-1715902 ◽

2020 ◽

Vol 33 (03) ◽

pp. 241-243

Author(s):

Rajesh Kovilacar ◽

Pankhuri Misra

Keyword(s):

Public Health ◽

Case Report ◽

Sore Throat ◽

Female Patient ◽

Public Health Emergency ◽

Positive Patient ◽

Number Of Patients ◽

Precautionary Measures ◽

Day By Day

Abstract Introduction The outbreak of coronavirus disease 2019 (COVID-19) has been declared as public health emergency of international concern. India is also facing this crisis with increasing number of patients being reported day by day. Here, we present a case report of COVID-19-positive patient treated with homoeopathy. Case Profile A 60-year-old female patient with fever for 4 days, cough and difficulty in breathing, headache, sore throat, loose stools and frequent urination with burning and generalised weakness for 7 days was considered for treatment in the present study. Based on the symptomatology, Arsenicum album 30 and Bryonia alba 30 were prescribed to her. Conclusion A patient of COVID-19 was successfully treated by homoeopathic medicines based on symptom similarity. Individualised homoeopathic intervention with precautionary measures can be an answer to the ongoing crisis.

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WINNING THE WAR AGAINST COVID-19 IN MALAYSIA: AN ACHIEVABLE GOAL?

Malaysian Journal of Public Health Medicine ◽

10.37268/mjphm/vol.20/no.1/art.493 ◽

2020 ◽

Vol 20 (1) ◽

pp. 148-149

Author(s):

Mohd Hafiz Jaafar ◽

Amirah Azzeri

Keyword(s):

Public Health ◽

Public Health Emergency ◽

World Health ◽

Cumulative Number ◽

Healthcare Resources ◽

Epidemic Curve ◽

Number Of Patients ◽

The World ◽

Achievable Goal ◽

Health Organization

The World Health Organization (WHO) has initially categorised COVID-19 infection as a Public Health Emergency of International Concern (PHEIC) in late January 2020 and later on declared the outbreak as a pandemic on March 11, 2020. On February 4, 2020 the first Malaysian positive COVID-19 patients was detected. It was estimated through a thorough decision tree technique, cumulatively 22,000 positive patients were expected to be infected nationwide. At the current rate of disease detection, screening yield and clinical capacity in Malaysia, the identification of the positive patients will have to be continuously done until middle of May 2020. In addition, a prediction with the forecasted testing capacity was also conducted. In contrast with the earlier estimation, massive testing causes the number of positive patients to be saturated earlier, by the end of April 2020. Based on the projection, 346, 307 cumulative tests will be conducted with 225,100 cumulative positive cases will be identified. Of the numbers, the cumulative number of patients in care would be 17,631 with 705 cumulative number of admission to intensive care unit and 353 cumulative patients required for ventilator. The cumulative death and cumulative discharge are expected to be 394 and 6008 respectively. Currently, it is challenging for Malaysia to flatten the epidemic curve due to the constraints of healthcare resources. These challenges potentially highlight the need for realistic strategies with regard to the country’s capacity.

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Case of COVID-19 in a 5-week-old baby

BMJ Case Reports ◽

10.1136/bcr-2020-236330 ◽

2020 ◽

Vol 13 (9) ◽

pp. e236330

Author(s):

Rachael Fleming ◽

Rosemary Grattan ◽

Kristyna Bohmova

Keyword(s):

Public Health ◽

Personal Protective Equipment ◽

Adult Population ◽

Paediatric Population ◽

Public Health Emergency ◽

Full Recovery ◽

Protective Equipment ◽

Paediatric Patients ◽

First Case ◽

Work Up

On 31 December 2019, the first case of COVID-19, was reported in Wuhan. A public health emergency of international concern was declared on 30 January 2020 and the first case in Scotland, on 2 March. The effect of COVID-19 appears to be less in the paediatric population and there are fewer cases reported in the literature in comparison to the adult population. Here, we report a case of a previously well 5-week-old infant who presented with fever and increased sleepiness. There was no known contact with any unwell individuals. COVID-19 was identified through a septic screen work up. The infant’s course was uneventful and she has made a full recovery. This case highlights the need to have a low index of suspicion in the diagnosis of COVID-19 and the need to be vigilant in use of personal protective equipment, even in paediatric patients with subtle symptoms.

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SARS-CoV-2 pandemic: potential relationship between psychiatric disorders and pulpits

Research Society and Development ◽

10.33448/rsd-v10i13.20372 ◽

2021 ◽

Vol 10 (13) ◽

pp. e97101320372

Author(s):

Rodrigo Arruda-Vasconcelos ◽

Lidiane Mendes Louzada ◽

Esdras Gabriel Alves-Silva ◽

Rebecca Figueiredo de Almeida-Gomes ◽

Henrico Badaoui Strazzi-Sahyon ◽

...

Keyword(s):

Public Health ◽

Quality Of Life ◽

Emergency Services ◽

Dental Health ◽

Public Health Emergency ◽

Global Public Health ◽

Number Of Patients ◽

Physical Disorders ◽

Dental Emergency

The coronavirus outbreak is a global public health emergency with high transmission among the population. Over 18 million people were affected globally (06th August 2020). In most of the cases, patients present flu-like symptoms, such as fever, cough, headaches and myalgias are commonly reported. Lockdown measures have been implemented to control the spread of the virus. In contrast, these measures have been reported to increase the probability of psychological and physical disorders. As the pandemic intensifies, the number of patients seeking dental emergency services due to acute symptoms (i.e. pulpitis, acute apical abscesses) has increased. There is an increasing need to investigate the association between psychological disorders and dental emergencies. There is critical need for the development of public policies for mental and dental health worldwide, leading to the improvement in the quality of life of the population.

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The effects of Personal, Environmental, and Genetic Factors on Epidemic of COVID-19: A Review of the Current Literature (Preprint)

10.2196/preprints.19211 ◽

2020 ◽

Author(s):

Hojatollah Kakaei 6th ◽

Salar Bakhtiyari ◽

Amin Mirzaei ◽

Sajad Mazloomi ◽

Mohsen Jalilian ◽

...

Keyword(s):

Public Health ◽

Genetic Factors ◽

Viral Disease ◽

Public Health Emergency ◽

World Health ◽

Number Of Patients ◽

The World ◽

Genetic And Environmental Factors ◽

Health Organization ◽

The City

UNSTRUCTURED COVID-19 is a viral disease that unfolded in the city of Wuhan, China, at the end of 2019. The global outbreak of the COVID-19 epidemic has prompted the World Health Organization to declare a public health emergency. The concerns about the COVID-19 disease are the rapid increase in the number of patients as well as the number of deaths compared with SARS disease. Given that there is a remarkable variability amongst people for COVID-19, there really is the possibility that there will be genetic and environmental effects, it is a necessity that their role should be absolutely identified as soon as possible. Various studies have been executed on the effects of genetic and environmental factors such as temperature and humidity on the constancy of the COVID-19 virus. In this review, we aimed to discuss the benefits and effects of these factors on COVID-19 in detail.

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Pneumothorax in critically COVID-19 patients with mechanical ventilation

Medical Journal of Indonesia ◽

10.13181/mji.cr.204798 ◽

2021 ◽

Author(s):

Allen Widysanto ◽

Titis Dewi Wahyuni ◽

Leonardo Helasti Simanjuntak ◽

Samuel Sunarso ◽

Sylvia Sagita Siahaan ◽

...

Keyword(s):

Public Health ◽

Mechanical Ventilation ◽

Acute Respiratory Distress Syndrome ◽

Respiratory Failure ◽

Distress Syndrome ◽

Public Health Emergency ◽

Protective Strategy ◽

Ventilator Settings

Coronavirus disease 2019 (COVID-19) is a public health emergency caused by SARS-CoV-2. A few studies reported pneumothorax in patients with COVID-19. Pneumothorax is associated with an increased morbidity and mortality. Hence, it should be considered during the treatment and follow-up of patients with COVID-19. Herein, we reported four cases of pneumothorax in critical COVID-19 patients hospitalized in the ICU and treated with a mechanical ventilation. All patients were diagnosed with COVID-19, type 1 respiratory failure, and acute respiratory distress syndrome. All patients developed pneumothorax during mechanical ventilation, although the ventilator settings were set to lung-protective strategy.

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