scholarly journals Mild behavioral impairment is related to frailty in non-dementia older adults: a cross-sectional study

2020 ◽  
Author(s):  
Shaoyi Fan ◽  
Ximin Liang ◽  
Tianchan Yun ◽  
Zhong Pei ◽  
Bin Hu ◽  
...  

Abstract Background: Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a dementia risk syndrome characterized by later-life emergence of persistent neuropsychiatric symptoms, has yet to be elucidated. We aimed to evaluate the associations between MBI and frailty in older adults without dementia.Methods: In this cross-sectional study, a consecutive series of 137 older adults without dementia in the Anti-Aging Study, recruited from primary care clinics, were enrolled. Frailty was estimated using the Fried phenotype. MBI was evaluated by the Mild Behavioral Impairment Checklist (MBI-C) at a cut-off point of >8. Cognition was assessed with the Chinese versions of the Montreal Cognitive Assessment (MoCA-BC) and Mini-mental State Examination (MMSE). Multivariable logistic regression was performed to estimate the relationship between MBI and objective cognition with frailty status.Results: At baseline, 30.7% of the older adults had frailty and 18.2% had MBI (MBI+ status). Multivariable logistic regression analysis demonstrated that compared to those without MBI (MBI- status), MBI+ was more likely to have frailty (odds ratio [OR] = 7.44, 95% CI = 1.49-37.21, p = 0.02). Frailty and MBI were both significantly associated with both MMSE and MoCA-BC score (p<0.05).Conclusions: Both frailty and MBI status were associated with higher odds of cognitive impairment. MBI was significantly associated with an increased risk of having frailty in the absence of dementia. This association merits further study to identify potential strategies for the early detection, prevention and therapeutic intervention of frailty.

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Shaoyi Fan ◽  
Ximin Liang ◽  
Tianchan Yun ◽  
Zhong Pei ◽  
Bin Hu ◽  
...  

Abstract Background Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a dementia risk syndrome characterized by later-life emergence of persistent neuropsychiatric symptoms, has yet to be elucidated. We aimed to evaluate the associations between MBI and frailty in older adults without dementia. Methods In this cross-sectional study, a consecutive series of 137 older adults without dementia in the Anti-Aging Study, recruited from primary care clinics, were enrolled. Frailty was estimated using the Fried phenotype. MBI was evaluated by the Mild Behavioral Impairment Checklist (MBI-C) at a cut-off point of > 8. Cognition was assessed with the Chinese versions of the Montreal Cognitive Assessment (MoCA-BC) and Mini-mental State Examination (MMSE). Multivariable logistic regression was performed to estimate the relationship between MBI and objective cognition with frailty status. Results At baseline, 30.7% of the older adults had frailty and 18.2% had MBI (MBI+ status). Multivariable logistic regression analysis demonstrated that compared to those without MBI (MBI- status), MBI+ was more likely to have frailty (odds ratio [OR] = 7.44, 95% CI = 1.49–37.21, p = 0.02). Frailty and MBI were both significantly associated with both MMSE and MoCA-BC score (p < 0.05). Conclusions Both frailty and MBI status were associated with higher odds of cognitive impairment. MBI was significantly associated with an increased risk of having frailty in the absence of dementia. This association merits further study to identify potential strategies for the early detection, prevention and therapeutic intervention of frailty.


2020 ◽  
Author(s):  
Shaoyi Fan ◽  
Ximin Liang ◽  
Tianchan Yun ◽  
Zhong Pei ◽  
Bin Hu ◽  
...  

Abstract Background: Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a dementia risk syndrome characterized by later-life emergence of persistent neuropsychiatric symptoms, has yet to be elucidated. We aimed to evaluate the associations between MBI and frailty in older adults without dementia.Methods: In this cross-sectional study, a consecutive series of 137 older adults without dementia in the Anti-Aging Study, recruited from primary care clinics, were enrolled. Frailty was estimated using the Fried phenotype. MBI was evaluated by the Mild Behavioral Impairment Checklist (MBI-C) at a cut-off point of >8. Cognition was assessed with the Chinese versions of the Montreal Cognitive Assessment (MoCA-BC) and Mini-mental State Examination (MMSE). Multivariable logistic regression was performed to estimate the relationship between MBI and objective cognition with frailty status.Results: At baseline, 30.7% of the older adults had frailty and 18.2% had MBI (MBI+ status). Multivariable logistic regression analysis demonstrated that compared to those without MBI (MBI- status), MBI+ was more likely to have frailty (odds ratio [OR] = 7.44, 95% CI = 1.49-37.21, p = 0.02). Frailty and MBI were both significantly associated with both MMSE and MoCA-BC score (p<0.05).Conclusions: Both frailty and MBI status were associated with higher odds of cognitive impairment. MBI was significantly associated with an increased risk of having frailty in the absence of dementia. This association merits further study to identify potential strategies for the early detection, prevention and therapeutic intervention of frailty.


2020 ◽  
Author(s):  
Shaoyi Fan ◽  
Ximin Liang ◽  
Tianchan Yun ◽  
Zhong Pei ◽  
Bin Hu ◽  
...  

Abstract Background: Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a neurobehavioral syndrome characterized by later-life emergence of sustained neuropsychiatric symptoms, has yet to be elucidated.We aimed to evaluate the associations between mild behavioral impairment and frailty in non-dementia older adults.Methods: This is a cross-sectional study. A consecutive series of 137 non-dementia older adults in the Anti-Aging Study, recruited from primary care clinics, were enrolled. Frailty was estimated using the Fried phenotype. MBI was evaluated by the Mild Behavioral Impairment Checklist at a cut-off point of >8 (optimizing sensitivity and specificity), which was developed to assess emergent neuropsychiatric symptoms in accordance with the MBI criteria. Cognition was assessed with the Chinese versions of the Montreal Cognitive Assessment (MoCA-BC) and Mini-mental State Examination (MMSE). Multivariate logistic regression was performed to estimate the relationship between MBI and objective cognition with frailty status.Results: At baseline, 30.7% of the older adults had frailty and 18.2% had MBI (MBI+ status). Multivariate logistic regression analysis demonstrated that compared to MBI- status (without MBI), MBI+ was more likely to have frailty (odds ratio [OR] = 7.44, 95% CI = 1.49-37.21, p = 0.02).Conclusions: MBI is significantly associated with an increased risk of having frailty before the presence of overt dementia. This association merits further study to identify strategies for the early detection, prevention and therapeutic intervention of frailty.


2020 ◽  
Author(s):  
Shaoyi Fan ◽  
Ximin Liang ◽  
Tianchan Yun ◽  
Zhong Pei ◽  
Bin Hu ◽  
...  

Abstract Background: Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a neurobehavioral syndrome characterized by later-life emergence of sustained neuropsychiatric symptoms, has yet to be elucidated.We aimed to evaluate the associations between mild behavioral impairment and frailty in cognitively normal older adults.Methods: This is a cross-sectional study. A consecutive series of 137 cognitively normal older adults in the Anti-Aging study, recruited from primary care clinics, were enrolled. Frailty was estimated using the original Fried phenotype. MBI was evaluated by the Mild Behavioral Impairment Checklist at a cut-off point of >8 (optimizing sensitivity and specificity), which was developed to assess emergent neuropsychiatric symptoms in accordance with the MBI criteria. Cognition was assessed with the Chinese versions of the Montreal Cognitive Assessment (MoCA-BC) and Mini-mental State Examination (MMSE). Multivariate logistic regression was performed to estimate the relationship between MBI and objective cognition with frailty status.Results: At baseline, 30.6% of the older adults had frailty, 35.0% had prefrailty and 18.2% had MBI (MBI+ status). Multivariate logistic regression analysis demonstrated that compared to MBI- status (without MBI), MBI+ was more likely to have frailty (odds ratio [OR] = 7.44, p = 0.02). The frailty and MBI categories were both significantly associated with both MMSE and MoCA-BC score (p<0.05).Conclusions: Both frailty and MBI status are related to higher risk of cognitive impairment. MBI is significantly associated with an increased risk of having frailty before overt cognitive impairment. This association merits further study to identify strategies to the early detection, prevention and therapeutic intervention of frailty.


Author(s):  
Yoshihiro Kugimiya ◽  
Masanori Iwasaki ◽  
Yuki Ohara ◽  
Keiko Motokawa ◽  
Ayako Edahiro ◽  
...  

Oral hypofunction, resulting from a combined decrease in multiple oral functions, may affect systemic-condition deterioration; however, few studies have examined the association between oral hypofunction and general health among older adults. In this cross-sectional study, we examined the relationship between oral hypofunction and sarcopenia in community-dwelling older adults. We included 878 adults (268 men and 610 women, mean age 76.5 ± 8.3 years). Tongue coating index, oral moisture, occlusal force, oral diadochokinesis (/pa/,/ta/,/ka/), tongue pressure, mas-ticatory function, and swallowing function were evaluated as indicators of oral hypofunction. Grip strength, gait speed, and skeletal muscle mass index were measured as diagnostic sarcopenia parameters. The association between oral hypofunction and sarcopenia was examined via logistic regression using sarcopenia as the dependent variable. Oral hypofunction prevalence was 50.5% overall, 40.3% in men, and 54.9% in women. The prevalence of sarcopenia was 18.6% overall, 9.7% in men, and 22.5% in women. A logistic regression showed oral hypofunction, age, body mass index, higher-level functional capacity, and serum albumin level were significantly associated with sarcopenia. Sarcopenia occurred at an increased frequency in patients diagnosed with oral hypofunction (odds ratio: 1.59, 95% confidence interval: 1.02–2.47); accordingly, oral hypofunction appears to be significantly associated with sarcopenia.


2020 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Udi Wahyudi ◽  
Bram Burnamajaya

Bullying merupakan perilaku negatif yang dilakukan secara berulang-ulang oleh seseorang atau sekelompok orang yang bersifat menyerang karena adanya ketidakseimbangan kekuatan antara pihak yang terlibat.Tindakan bullying dapat berdampak buruk bagi korban maupun pelakunya di masa depannya. Dampak tersebut meliputi kesepian, pencapaian akademik yang buruk, kesulitan penyesuaian (adaptasi), meningkatnya risiko penggunaan zat, keterlibatan dalam tindakan kriminal dan kerentanan gangguan mental emosional seperti cemas, insomnia, penyalahgunaan zat, depresi, mempunyai self-esteem rendah, kesulitan interpersonal, gangguan konsep diri, dan depresi (ketidakberdayaan). Tujuan penelitian ini adalah untuk mengetahui hubungan antara konsep diri dan ketidakberdayaan dengan risiko bunuh diri pada remaja yang mengalami bullying di SMA Negeri 7 Kota Bogor. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan metode cross-sectional study dengan bentuk pendekatan rancangan correlation study. Sampel dalam penelitian ini berjumlah 183 orang didapat dari teknik randomsampling. Hasil penelitian menunjukkan bahwa berdasarkan hasil uji hubungan dengan menggunakan Chi-Square antara konsep diri dengan ketidakberdayaan didapatkan nilai ρ (0,000) lebih kecil daripada nilai α (0,05), sedangkan uji hubungan antara konsep diri dengan risiko bunuh diri didapatkan nilai ρ (0,013) lebih kecil daripada nilai α (0,05). Dengan demikian bahwa ada hubungan antara konsep diri dan ketidakberdayaan dengan risiko bunuh diri pada remaja yang mengalami bullying di SMA Negeri 7 Kota Bogor. Kata kunci: bullying, konsep diri, ketidakberdayaan, risisko bunuh diri SELF-CONCEPT AND INEQUALITY CONNECTED WITH RISK OF SELF-SUFFICIENT IN ADOLESCENTS WHO HAVE BULLYING ABSTRACTBullying is a negative behavior that is carried out repeatedly by a person or group of people who are attacking because of an imbalance of power between the parties involved. Bullying actions can have a negative impact on victims and perpetrators in the future. These impacts include loneliness, poor academic achievement, adaptation difficulties, increased risk of substance use, involvement in criminal acts and susceptibility to mental emotional disorders such as anxiety, insomnia, substance abuse, depression, low self-esteem, interpersonal difficulties, disturbances self concept, and depression (helplessness). The purpose of this study was to determine the relationship between self-concept and powerlessness with the risk of suicide in adolescents who experienced bullying in SMA Negeri 7 Kota Bogor. This research is a quantitative study using a cross-sectional study method with a correlation study design approach. The sample in this study amounted to 183 people obtained from random sampling techniques. The results showed that based on the results of the relationship test using Chi-Square between self-concept and powerlessness, the value of ρ (0,000) was smaller than the value of α (0.05), while the test of the relationship between self-concept and risk of suicide obtained a value of ρ (0.013 ) is smaller than the value of α (0.05). Thus that there is a relationship between self-concept and powerlessness with the risk of suicide in adolescents who experience bullying in SMA Negeri 7 Kota Bogor. Keywords: bullying, self-concept, helplessness, suicide risk


2019 ◽  
Vol 7 (2) ◽  
pp. 133-138 ◽  
Author(s):  
Mohabbat Mohseni ◽  
Abedin Iranpour ◽  
Ahmad Naghibzadeh-Tahami ◽  
Leila Kazazi ◽  
Vahidreza Borhaninejad

2021 ◽  
Vol 21 (2) ◽  
pp. 88-94
Author(s):  
Priyadarshini Ramamurthy ◽  
Bennete Fernandes ◽  
Avita Rath

The aim of this study was to determine the prevalence and patterns of tobacco use among health sciences undergraduate students. A cross-sectional study was conducted among 422 students in four health sciences faculties at a private university in Kota Damansara, Selangor Malaysia. Data was collected through a self-administrated validated questionnaire, adopted and modified from the Global Youth Tobacco Survey. The survey  was administered online  using a Google Form for the participants to fill. Data was analysed using SPSS version 22. Descriptive statistics was used to express results in percentage. Chi-square test and multivariable logistic regression was used to test the association of smoking status and demographic variables. p value of <0.05 was considered as statistically significant. Results showed that more than 90% of the respondents were aware of the harmful effects of tobacco and effects of passive smoking. About one fifth of the participants had used tobacco (19%) in our study. Out of the tobacco users, 95% had used tobacco in more than one form. The most important reasons for smoking were peer pressure (36%) and stress (35%). No significant differences were found between age,  faculty, year of study, or nationality, with the use of tobacco. Multivariable logistic regression analysis showed significant gender differences in smoking with more smokers among males than females. In conclusion, about one fifth of the health science undergraduate students had  used tobacco products in our study reflecting a seemingly inappropriate portrait as compared to their future careers as health professionals. Therefore, there is an urgent need for reinforcement of education and assistance on quitting tobacco usage among the undergraduates of health science faculties.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Sailimai Man ◽  
Yuan Ma ◽  
Cheng Jin ◽  
Jun Lv ◽  
Mingkun Tong ◽  
...  

Background. Studies suggest an association between H. pylori infection and extragastrointestinal disease. Limited studies provided conflicting results on the association between H. pylori infection and diabetes. The present study was aimed at examining the association between H. pylori infection and diabetes in a large health checkup population in China. Methods. A cross-sectional study was conducted; participants who attended health checkups at Beijing MJ Health Screening Center during 2017-2018 were included. H. pylori infection was diagnosed by 13C-urea breath test. Multivariate logistic regression analysis was performed to evaluate the association between H. pylori infection and diabetes. Results. The mean age of 13,397 participants was 43.8±12 years. The prevalence of H. pylori infection and diabetes was 28.2% and 8.1%, respectively. The prevalence of diabetes was higher among H. pylori-positive participants compared with their counterparts (8.9% vs 7.8%, p=0.05). After adjustment of age, sex, family history of diabetes, smoking, education, stroke, coronary heart disease, BMI, SBP, TG, HDL-C, and LDL-C, multivariate logistic regression analysis found no association between H. pylori infection and diabetes (OR 1.02, 95% CI 0.88-1.18). Additionally, subgroup analysis indicated that H. pylori infection was significantly associated with increased risk of diabetes in the female group (OR 1.09, 95% CI 1.08-1.09). Conclusions. No significant association was found between H. pylori infection and diabetes. However, the subgroup analysis suggested that H. pylori infection was possibly associated with increased risk of diabetes among females. Future cohort studies are needed to verify this association in females and to address possible implication in the prevention of diabetes.


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