scholarly journals The Importance of Building Community Trust for Sustained Malaria Elimination Interventions During Unforeseen Major Disruptive Events Such as COVID-19: A Cambodia Case Study

2020 ◽  
Author(s):  
Mitra Feldman ◽  
Lieven Vernaeve ◽  
James Tibenderana ◽  
Leo Braack ◽  
Mark Debackere ◽  
...  
Keyword(s):  
Rural Communities ◽  
Malaria Elimination ◽  
The Novel ◽  
National Guidelines ◽  
Patients At Risk ◽  
Building Community ◽  
Novel Coronavirus ◽  
High Level ◽  
First Time

Abstract Background Impressive progress in reducing malaria trends combined with the 2018 report of no malaria related deaths for the first time, puts Cambodia well on track to reaching its malaria elimination goals. However, the novel coronavirus SARS-CoV-2 (COVID-19) pandemic presents a potential challenge to this goal. The path towards malaria elimination is dependent on sustained interventions to prevent rapid resurgence, which can quickly set back any gains achieved. Methods Mobile Malaria Workers (MMWs) need to have a strong understanding of the local geography and, most importantly, build and maintain trust among the communities they serve. To achieve this, Malaria Consortium uses a peer-to-peer approach for the MMWs and ensures the same level of trust operates between the MMWs and Malaria Consortium. Malaria Consortium’s policy during COVID-19 has been to follow national guidelines while continuing to support community-based malaria services via the MMWs / mobile malaria posts (MPs) with as minimal disruption as possible. A risk assessment was carried out by Malaria Consortium, with a mitigation plan quickly developed and implemented, to ensure MMWs were able to continue providing services without putting themselves or their patients at risk. Results Malaria Consortium ensured the MMW/ mobile MP program is built on trust, relevance to, and connection with the communities being served. An overall decline in malaria testing was reported from Health Centres and VMWs among all three provinces in March and April, not seen in previous years and possibly attributable to fear of COVID-19. However, Malaria Consortium supported MMWs have not reported any such decline in the utilization of their services and attribute this to the trust they have among the communities. Conclusion Malaria Consortium has effectively demonstrated care and solidarity with and among the MMWs and communities being served. This has ensured a high level of trust, and therefore willingness among the MMWs and communities to continue providing and utilising malaria services as usual despite the fear of COVID-19. Building trust among rural communities builds resilience and ensures uninterrupted and effective malaria elimination activities can continue even during a potential extraneous disruptive force, such as the Covid-19 pandemic.

scholarly journals The importance of building community trust for sustained health interventions during disruptive events such as COVID-19: A Cambodia case study

2020 ◽  
Author(s):  
Mitra Feldman ◽  
Lieven Vernaeve ◽  
James Tibenderana ◽  
Mark Debackere ◽  
Leo Braack ◽  
...  
Keyword(s):  
Rural Communities ◽  
Malaria Elimination ◽  
Mitigation Measures ◽  
The Novel ◽  
National Guidelines ◽  
Building Community ◽  
Novel Coronavirus ◽  
High Level ◽  
First Time

Abstract Cambodia has made impressive progress in reducing malaria trends and, in 2018, reported no malaria related deaths for the first time. However, the novel coronavirus SARS-CoV-2 (COVID-19) pandemic presents a potential challenge to the country’s goal for malaria elimination by 2025. The path towards malaria elimination is dependent on sustained interventions to prevent rapid resurgence, which can quickly set back any gains achieved. Malaria Consortium supported Mobile Malaria Workers (MMWs) engage with target communities to promote acceptance, trust, and resilience. During the COVID-19 pandemic Malaria Consortium’s policy has been to follow national guidelines while continuing to support community-based malaria services via the MMWs / mobile malaria posts (MPs) with as minimal disruption as possible. A COVID-19 risk assessment was carried out by Malaria Consortium, with a mitigation plan quickly developed and implemented, to ensure MMWs were able to continue providing services without putting themselves or their patients at risk.In general, Health Centres and village malaria workers at District level saw an overall decline in malaria testing in March and April; however, Malaria Consortium-supported MMWs did not report any such decline in the utilization of their services. They attribute this to the trust they have among the communities especially regarding Covid-19 mitigation measures that were implemented, and their consequent ability to continue working safely thanks to Malaria Consortium’s rapid response and continued support.By effectively demonstrating care and solidarity with and among the MMWs and communities being served, the rapid and effective Covid-19 mitigation measures and community messaging have ensured a high level of trust, and therefore willingness to continue providing and utilising malaria services as usual, despite the fear of COVID-19. By building trust among rural communities, resilience was strengthened, and effective malaria elimination activities were able to continue uninterrupted, even during an extraneous disruptive force such as the Covid-19 pandemic.

scholarly journals Building Telemedicine Capacity for Trainees During the Novel Coronavirus Outbreak: a Case Study and Lessons Learned

2020 ◽  
Vol 35 (9) ◽  
pp. 2675-2679 ◽  
Author(s):  
Katharine Lawrence ◽  
Kathleen Hanley ◽  
Jennifer Adams ◽  
Daniel J Sartori ◽  
Richard Greene ◽  
...  
Keyword(s):  
Lessons Learned ◽  
The Novel ◽  
Novel Coronavirus

scholarly journals Pulmonary Cavitation – An Under-recognized Late Complication of Severe COVID-19 Lung Disease

2020 ◽  
Author(s):  
Zaid Zoumot ◽  
Maria-Fernanda Bonilla ◽  
Ali S. Wahla ◽  
Irfan Shafiq ◽  
Mateen Uzbeck ◽  
...  
Keyword(s):  
Lung Disease ◽  
Medical Records ◽  
Late Complication ◽  
Ground Glass ◽  
The Novel ◽  
Radiological Findings ◽  
Imaging Characteristics ◽  
Microbiological Parameters ◽  
Novel Coronavirus ◽  
High Level

Abstract Background: Pulmonary radiological findings of the novel coronavirus disease 2019 (COVID-19) have been well documented and range from scattered ground-glass infiltrates in milder cases to confluent ground-glass change, dense consolidation, and crazy paving in the critically ill. However, lung cavitation has not been commonly described in these patients. The objective of this study was to assess the incidence of pulmonary cavitation in patients with COVID-19 and describe its characteristics and evolution.Methods: We conducted a retrospective review of all patients admitted to our institution with COVID-19 and reviewed electronic medical records and imaging to identify patients who developed pulmonary cavitation.Results: Twelve out of 689 (1.7%) patients admitted to our institution with COVID-19 developed pulmonary cavitation, comprising 3.3% (n=12/359) of patients who developed COVID-19 pneumonia, and 11% (n=12/110) of those admitted to the intensive care unit. We describe the imaging characteristics of the cavitation and present the clinical, pharmacological, laboratory, and microbiological parameters for these patients. In this cohort six patients have died, two are recovering in hospital and four have been discharged home. Conclusion: Cavitary lung disease in patients with severe COVID-19 disease is not uncommon, and is associated with a high level of morbidity and mortality.

First application of the marine differential electric dipole for groundwater investigations: A case study from Bat Yam, Israel

Geophysics ◽  
2018 ◽  
Vol 83 (2) ◽  
pp. B59-B76 ◽  
Author(s):  
Amir Haroon ◽  
Klaus Lippert ◽  
Vladimir Mogilatov ◽  
Bülent Tezkan
Keyword(s):  
Electric Dipole ◽  
Coastal Region ◽  
Natural Phenomenon ◽  
The Novel ◽  
Aquifer System ◽  
Transient Electromagnetic ◽  
Long Offset ◽  
Lateral Extent ◽  
First Time

The marine differential electric dipole (DED) is applied for the first time to study a subseafloor groundwater body in the coastal region of Bat Yam, Israel. Previous marine long-offset transient electromagnetic applications detected this freshwater body underneath the Mediterranean seafloor. We have applied the novel DED method for the first time in the marine environment to further investigate this natural phenomenon. The main objectives are to locate the freshwater-seawater interface at the western aquifer edge and to identify the mechanism controlling this freshwater occurrence beneath the seafloor. The acquired step-on signals allow one to detect the freshwater body in the vicinity of the Israeli coastline at a depth of approximately 70 m beneath the seafloor. However, aquifer thickness is only poorly determined and may vary between 40 and 100 m. A lateral resistivity contrast is observable between adjacent 1D inversion models and also apparent in data profile curves that constrain the seaward extent of the detected resistive body to a distance of less than 4 km from the coastline. A subsequent 2.5D forward-modeling study aims to find a subseafloor resistivity distribution that adequately explains all measured DED data simultaneously. The results further constrain the lateral extent of the resistive aquifer to approximately 3.6–3.7 km from the Israeli coast. Furthermore, the data indicate that the aquifer system may be susceptible to seawater intrusion, as a superior data fit is achieved if a brackish water zone of approximately [Formula: see text] with a lateral extent of less than 300 m is located at the head of the freshwater body.

Assessing Impacts to National Park Visitation From COVID-19

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Jeffrey Jenkins ◽  
Felber Arroyave ◽  
Madeline Brown ◽  
Jullianna Chavez ◽  
Johnny Ly ◽  
...  
Keyword(s):  
National Park ◽  
The Novel ◽  
National Guidelines ◽  
Visitor Experiences ◽  
Case Count ◽  
Park Visitation ◽  
Reservation System ◽  
Novel Coronavirus ◽  
Entry Restrictions ◽  
Permit System

Yosemite National Park is a popular tourist destination with high visitation levels that have increased throughout the summer season over the past several decades. Like with other protected areas, high visitation levels pose challenges for coordinating resources, infrastructural capacity, and visitor experiences. Use limits, including rationing vehicle entry at gates by reservation, are one possible strategy to manage visitation levels. After an initial full closure, the park chose to operationalize a multiphased permit system for day-use and overnight entry over the course of the pandemic in accordance with local and national guidelines for operational safety. While park closures and other entry restrictions have been common in recent years due to wildland fires and other natural hazards, the pandemic-related entry limits represent a nearly yearlong experiment. The prolonged entry ration along with restrictions to group activities has limited visitation and potentially reduced transmission of the novel coronavirus. We review the per capita COVID-19 case count in surrounding counties given the flow of tourism from outside the region, assess the changes in access to the park with the novel reservation system, compare monthly visitation during the 2020 use limits with prior decadal averages, detail how high visitation levels and crowding persist, and review the Park’s plans for an ongoing day-use permit system. We conclude with the ongoing challenges managers face in light of continued high visitation. Readers will be able to debate the efficacy of use limits and what may be a sustainable level of visitation for the park.

scholarly journals Targeting the sAC-Dependent cAMP Pool to Prevent SARS-Cov-2 Infection

Cells ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1962
Author(s):  
Muhammad Aslam ◽  
Yury Ladilov
Keyword(s):  
Endocytic Pathway ◽  
Host Cells ◽  
The Novel ◽  
Cellular Mechanisms ◽  
Late Endosomes ◽  
Proven Efficacy ◽  
Potential Impact ◽  
Potential Strategy ◽  
Novel Coronavirus ◽  
High Level

An outbreak of the novel coronavirus (CoV) SARS-CoV-2, the causative agent of COVID-19 respiratory disease, infected millions of people since the end of 2019, led to high-level morbidity and mortality and caused worldwide social and economic disruption. There are currently no antiviral drugs available with proven efficacy or vaccines for its prevention. An understanding of the underlying cellular mechanisms involved in virus replication is essential for repurposing the existing drugs and/or the discovery of new ones. Endocytosis is the important mechanism of entry of CoVs into host cells. Endosomal maturation followed by the fusion with lysosomes are crucial events in endocytosis. Late endosomes and lysosomes are characterized by their acidic pH, which is generated by a proton transporter V-ATPase and required for virus entry via endocytic pathway. The cytoplasmic cAMP pool produced by soluble adenylyl cyclase (sAC) promotes V-ATPase recruitment to endosomes/lysosomes and thus their acidification. In this review, we discuss targeting the sAC-specific cAMP pool as a potential strategy to impair the endocytic entry of the SARS-CoV-2 into the host cell. Furthermore, we consider the potential impact of sAC inhibition on CoV-induced disease via modulation of autophagy and apoptosis.

scholarly journals Student-Designed Cross-Sectional Pandemic Knowledge Survey of 8th−12th Grade Students, Milwaukee, WI, April 2020

2021 ◽  
Vol 9 ◽  
Author(s):  
Krish Vasudev ◽  
Hersh Singh ◽  
August A. Neumann ◽  
William M Zhao ◽  
Lyle Dominic Pelayo Mondano
Keyword(s):  
The Novel ◽  
Cross Sectional ◽  
Safety Measures ◽  
Web Based ◽  
12Th Grade ◽  
Twelfth Grade ◽  
Level Of Understanding ◽  
Novel Coronavirus ◽  
High Level ◽  
Knowledge Survey

Background: The novel coronavirus and its effect on our society are unprecedented. Given the recent pandemic, numerous measures have been taken to protect our communities. We sought to understand our school community's knowledge and the measures that were taken by our school for our safety.Objective: Our objective was to describe the overall understanding and attitudes of 8–12th grade students from a single institution during the initial phase of the Wisconsin's Governor's stay-at-home order.Methods: A voluntary web-based survey was communicated to 8–12th grade students through their online school portal. Data were collected and analyzed using SurveyMonkey.Results: There was a 20.2% response rate. Answers regarding the coronavirus, spread, and response to the coronavirus pandemic showed a high level of understanding of the virus and the actions necessary to prevent its spread.Conclusion: Eight-twelfth grade students have a high level of understanding of the virus, its effects, and the safety measures implemented to protect society.

scholarly journals The methods of training of the Patrol-Guard Service officers in the midst of the novel coronavirus infection

2020 ◽  
pp. 64-72
Author(s):  
Maxim Yurevich Koynov
Keyword(s):  
Distance Learning ◽  
Blended Learning ◽  
Practical Training ◽  
The Novel ◽  
Distance Teaching ◽  
Learning Techniques ◽  
Coronavirus Infection ◽  
Level Of Training ◽  
Novel Coronavirus ◽  
High Level

The research subject is the methods of practical training of the Patrol-Guard Service officers via in-person learning and the inclusion of the distance learning techniques in the midst of the novel coronavirus infection (COVID-19). The research object is legal relations emerging in the process of formation of new educational methods in the midst of the novel coronavirus infection (COVID-19). The author analyzes the situation in the educational sphere connected with the use of various elements of in-person and distance teaching of the Patrol-Guard Service officers. The scientific novelty of the research consists in the consideration of elements of in-person and distance learning and in searching for the balance between these types of learning, and in the formation of the concept of blended learning and the analysis of its effectiveness in the current situation. The author’s contribution to the study of the topic is the analysis of the possibility to integrate blended learning and theoretical distance learning at the first stage, and practical in-person learning at the second stage into the system of block-module-based education used at the educational institutions of the Ministry of Internal Affairs of Russia. The author concludes that the use of the blended method of teaching allows achieving a high-level of training of the Patrol-Guard Service officers in the period of restrictions caused by the novel coronavirus infection (COVID-19).   

scholarly journals SARS-CoV-2 Infection as a Cause of Acute Pancreatitis in a Child—A Case Report

2021 ◽  
Vol 13 (4) ◽  
pp. 552-557
Author(s):  
Natalia Kopiczko ◽  
Kamila Kwiatek-Średzińska ◽  
Mirosława Uścinowicz ◽  
Monika Kowalczuk-Krystoń ◽  
Dariusz Marek Lebensztejn
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
The Novel ◽  
Gastrointestinal Manifestations ◽  
Number Of Patients ◽  
Growing Body ◽  
Novel Coronavirus ◽  
Mild Acute Pancreatitis ◽  
First Time

The novel coronavirus disease (COVID-19) was detected for the first time in China in December 2019. Soon after it was declared a pandemic. Main symptoms include fever, dyspnea, cough, muscle pain, headache, anosmia and ageusia, however a growing body of evidence shows that other organs can be affected. Gastrointestinal manifestations have been observed in a considerable number of patients and include abdominal pain, diarrhea and vomiting. The involvement of liver as well as pancreas has been also described, however there are only a few cases of acute pancreatitis reported in patients with COVID-19. Therefore, we present a case of 6-year-old child with mild acute pancreatitis and COVID-19 pneumonia.

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