scholarly journals Magnetic Resonance Imaging in the evaluation of Vasculopathy in the Morning Glory Anomaly.

Author(s):  
gordon heller

Abstract Morning Glory Anomaly is rare but its fundoscopic findings are well documented in the ophthalmologic literature. It is sporadic, without sexual predisposition and usually unilateral. Furthermore, it is associated with numerous central nervous system anomalies, including vasculopathy of the central nervous system. This case series reports four pediatric patients over a three year period in which ophthalmologic evaluation identified Morning Glory Anomaly. Magnetic Resonance Imaging (MRI) and Magnetic Resonance Angiography (MRA) were subsequently obtained to assess for associated intracranial vascular anomalies. This report is of significance as it demonstrates the spectrum of intracranial vasculopathy in this rare entity.

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Carlos Pérez-Serrano ◽  
Álvaro Bartolomé ◽  
Núria Bargalló ◽  
Carmen Sebastià ◽  
Alfons Nadal ◽  
...  

AbstractCentral nervous system (CNS) abnormalities cause approximately 32–37.7% of terminations of pregnancy (TOP). Autopsy is currently the gold standard for assessing dead foetuses and stillborn. However, it has limitations and is sometimes subject to parental rejection. Recent studies have described post-mortem foetal magnetic resonance imaging (MRI) as an alternative and even complementary to autopsy for CNS assessment. Radiologists now play a key role in the evaluation of perinatal deaths. Assessment of foetal CNS abnormalities is difficult, and interpretation of foetal studies requires familiarisation with normal and abnormal findings in post-mortem MRI studies as well as the strengths and limitations of the imaging studies. The purpose of this pictorial review is to report our experience in the post-mortem MRI evaluation of the CNS system, including a description of the protocol used, normal CNS findings related to post-mortem status, abnormal CNS findings in our sample, and the correlation of these findings with histopathological results.


Lupus ◽  
2017 ◽  
Vol 26 (13) ◽  
pp. 1440-1447 ◽  
Author(s):  
M Rodrigues ◽  
O Galego ◽  
C Costa ◽  
D Jesus ◽  
P Carvalho ◽  
...  

Central nervous system (CNS) vasculitis (CNS) in systemic erythematosus lupus (SLE) is a rare and challenging diagnosis. We report four cases of CNS vasculitis that occurred 5 to 16 years after the diagnosis of SLE. Magnetic resonance imaging (MRI) detected different features suggestive of CNS vasculitis: enhancement and thickening of the vascular wall, vascular stenosis, ischemic brain lesions and intracerebral haemorrhage unlikely to correspond to other mimic aetiologies. Three patients received combination therapy with glucocorticoids (GC) and cyclophosphamide (CYC). Intravenous human immunoglobulin (IVIG) was administered when the patient had a past history of serious adverse event to CYC or high infectious risk. All patients showed imagiological improvement, at least partially, 5 to 23 days after starting treatment. We discuss the management of CNS in SLE including the role of magnetic resonance imaging (MRI).


2016 ◽  
Vol 4 ◽  
pp. 2050313X1666623 ◽  
Author(s):  
Satiro Nakamura De Oliveira ◽  
Ignacio Gonzalez-Gomez ◽  
Ashok Panigrahy ◽  
Mark Krieger ◽  
Gordon McComb ◽  
...  

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Jakub Majchrzycki ◽  
Agnieszka Permoda-Pachuta ◽  
Martyna Wachowiak

Objectives. Broad neuroimaging studies currently play an important role in the understanding of the principles of the functioning of the central nervous system (CNS). This applies not only to the healthy nervous system, but also to many pathological processes responsible for neurological and psychiatric disease entities. Magnetic resonance imaging (MRI) as a diagnostic imaging method has been used in medicine since the 1970s. Currently, the diagnosis of mental disorders and the choice of treatment methods are based primarily on the patient’s history, a structured interview and ancillary psychological tests. However, there is still a lack of more objective methods that can solve many diagnostic problems. Literature review. The aim of this paper is to present the methods of diagnosis by means of magnetic resonance imaging, helpful in many aspects of work with a patient diagnosed with a mental disorder. The paper reviews the literature on specific MRI techniques, such as volumetry, proton magnetic resonance spectroscopy, diffusion-weighted MR (DMR), fMRI (functional magnetic resonance imaging), MRI with magnetisation transfer coefficient, and tractography, which may open up new possibilities, also for psychiatry. Because of the large number of papers in this field, the focus was on three psychiatric disorders, i.e. schizophrenia and unipolar and bipolar affective disorder. Conclusions. It seems likely that in future magnetic resonance imaging of the central nervous system may make it possible not only to differentiate between mental disorders or to forecast their course, but also to determine the effectiveness of treatment of mental disorders and to predict possible side effects of the applied pharmacotherapy or electrotherapy.


2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Hai chao FU

Susceptibility weighted imaging (SWI) is a relatively new magnetic resonance imaging (MRI) technique that uses the difference in tissue magnetic susceptibility to image, and has unique value compared to traditional magnetic resonance imaging. This article summarizes its application in the central nervous system and provides a reference for imaging diagnosis and clinical treatment.


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