Systematic review recommends the European Organization for Research and Treatment of Cancer colorectal cancer–specific module for measuring quality of life in colorectal cancer patients

Aim: To describe quality life’s colorectal cancer patients who are being treated at Thai Nguyenoncology center from June 2020 to August 2020.Objects and method: The descriptive cross- sectional study was conducted over 68 patientsdiagnosed with colorectal cancer by face to face interview using the European Organization forResearch and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-CR29.Results: Mean of overall health score was 51,96±18,78; mean of functional score was 21,49±12,42(1,71–47,06). In functional sector, social function was scored lowest. In symptomatic scale, appetiteloss was scored highest (47,06).Conclusion: Quality of life of colorectal cancer patients was medium level. Highest scores wereobserved for appetite loss and fatigue. To improve quality life’s patients, medical staffs need to keepenhancing symptoms and function for patients during treatment.

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Construct Validity and Reliability of the European Organization for Research and Treatment of Cancer Quality of Life Tool Among Colorectal Cancer Patients in Ethiopia

10.21203/rs.3.rs-623547/v1 ◽

2021 ◽

Author(s):

Lidya Genene Abebe ◽

Abigiya Wondimagegnehu ◽

Aynalem Abraha Woldemariam ◽

Bizu Gelaye ◽

Eva Johanna Kantelhardt ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Construct Validity ◽

Cancer Patients ◽

Life Questionnaire ◽

Validity And Reliability ◽

European Organization ◽

Eortc Qlq ◽

Colorectal Cancer Patients

Abstract Background: Colorectal cancer and its treatments can have a detrimental effect on patients’ quality of life. The European Organization for Research and Treatment of Cancer Quality of Life questionnaire (EORTC-QLQ) was developed to assess quality of life among colorectal cancer patients and is used worldwide. However, the tool has not been translated into a local language or validated in the Ethiopian context. Therefore, this study aimed to examine the psychometric properties of the EORTC-QLQ in Ethiopia among colorectal cancer patients.Methods: A cross-sectional study was conducted in a major referral hospital in Addis Ababa, Ethiopia from March to May, 2020. A total of 158 colorectal cancer patients were consecutively included. The construct validity was assessed using Multitrait Scale Analysis, convergent validity, and relationship with functional outcomes. The internal consistency was examined using Cronbach’s alpha.Result: Among the participants, 52.2% were men, with a median age of 46 years (IQR = 17.7 years). The time needed to complete the EORTC-QLQ was less than 20 minutes. The item-total correlation alpha values ranged from 0.47–0.91. All item correlations within their scales were greater than 0.4 except for the Blood and Mucus in Stool scale. The value of correlation coefficients between all items and their own domain were higher than other domains, except for the Blood and Mucus in Stool scale. The correlation between the core questionnaire and the colorectal tool ranged from -0.453–0.581. The tool showed a significant difference between stoma and non-stoma patients, and between patients who had good physical function and those who did not.Conclusion: Except for the Blood and Mucus in Stool scale, the construct validity and reliability of all scales were supported. Therefore, the Amharic version of the tool can be used to assess health related quality of life in Ethiopian colorectal cancer patients. However, due to the low correlation between items in the Blood and Mucus in Stool scale, we recommend that these items are treated as a single item.

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European Organization for Research and Treatment of Cancer QLQ-C30 and Functional Assessment of Cancer Therapy-General for the Measurement of Quality of Life in Colorectal Cancer Patients who Received Adjuvant Chemotherapy: A Comparison

Annals of Oncology ◽

10.1016/s0923-7534(20)33093-3 ◽

2012 ◽

Vol 23 ◽

pp. ix211

Author(s):

A. Tsunoda ◽

Y. Tsunoda

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Adjuvant Chemotherapy ◽

Cancer Therapy ◽

Cancer Patients ◽

Functional Assessment ◽

European Organization ◽

Colorectal Cancer Patients

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Time after ostomy surgery and type of treatment are associated with quality of life changes in colorectal cancer patients with colostomy

PLoS ONE ◽

10.1371/journal.pone.0239201 ◽

2020 ◽

Vol 15 (12) ◽

pp. e0239201

Author(s):

Karine de Almeida Silva ◽

Arenamoline Xavier Duarte ◽

Amanda Rodrigues Cruz ◽

Lúcio Borges de Araújo ◽

Geórgia das Graças Pena

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Cancer Patients ◽

Negative Influence ◽

Dry Mouth ◽

European Organization ◽

Treatment Type ◽

Colorectal Cancer Patients ◽

Clinical Changes

Purpose Quality of life in colorectal cancer patients may be affected by colostomy and treatment, but relevant studies are still scarce and contradictory. The present study aimed to evaluate the association between colostomy time and treatment type with quality of life in colorectal cancer patients. Methods A prospective observational study of 41 patients with colorectal cancer was conducted on three occasions T0, T1 and T2 (0–2; 3–5 and 6–8 months after ostomy surgery, respectively). The treatments prescribed were: surgery alone, chemotherapy or radiotherapy, or chemoradiotherapy. European Organization for Research and Treatment of Cancer questionnaires were used to evaluate quality of life. Worsening clinical changes were evaluated considering difference in scores between times of surgery ≥±9 points. Results Regarding ostomy surgery, scores in physical function improved between T0 and T1 and these better scores were maintained at T1 to T2. The same was observed for urinary frequency, appetite loss and dry mouth. Chemoradiotherapy was associated with worse scores for global health status, nausea and vomiting, bloating and dry mouth. Although significant differences were not observed in some domains in the Generalized Estimating Equations analysis, patients showed noticeable changes for the worse in the pain, anxiety, weight concern, flatulence and embarrassment domains during these periods. Conclusions Colostomy improved quality of life at 3–5 months in most domains of quality of life and remained better at 6–8 months after surgery. Chemoradiotherapy had a late negative influence on quality of life. Health teams could use these results to reassure patients that this procedure will improve their quality of life in many functional and symptomatic aspects.

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Safety and Quality of Life in the Treatment of Non-metastasic Colorectal Cancer Patients: 5-fluorouracil Versus Capecitabine

10.28991/iccr-2019-006 ◽

2019 ◽

Author(s):

Julia Sánchez-Gundín ◽

Cristina Martín-Sabroso ◽

Ana M. Fernández-Carballido ◽

D. Barreda-Hernández ◽

Ana I. Torres-Suárez

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Cancer Patients ◽

Colorectal Cancer Patients

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Are gender-associated differences in quality of life in colorectal cancer patients disease-specific?

Quality of Life Research ◽

10.1007/s11136-009-9468-0 ◽

2009 ◽

Vol 18 (5) ◽

pp. 547-555 ◽

Cited By ~ 15

Author(s):

Johannes Giesinger ◽

Georg Kemmler ◽

Verena Mueller ◽

August Zabernigg ◽

Beate Mayrbaeurl ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Cancer Patients ◽

Colorectal Cancer Patients ◽

Disease Specific

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Depression, Fatigue, and QoL in Colorectal Cancer Patients During and After Treatment

Western Journal of Nursing Research ◽

10.1177/0193945916630256 ◽

2016 ◽

Vol 38 (7) ◽

pp. 893-908 ◽

Cited By ~ 8

Author(s):

Hong-Yi Tung ◽

Tung-Bo Chao ◽

Yu-Hua Lin ◽

Shu-Fen Wu ◽

Hui-Yen Lee ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Health Care ◽

Cancer Patients ◽

Health Care Professionals ◽

Nursing Intervention ◽

Prevalence Of Depression ◽

Study Population ◽

Colorectal Cancer Patients

In this study, we sought to explore the prevalence of depression and fatigue in colorectal cancer patients during and after treatment to examine how these variables affect quality of life (QoL). In total, 170 patients with colorectal cancer participated in this study. The study population was divided into two groups: one receiving treatment and another that had finished treatment. The results showed that depression and fatigue measurements were higher in patients receiving treatment. Depression was a strong and significant predictor of QoL in both groups, whereas fatigue was not, with the exception of the symptom score. These findings underscore the importance of early detection and management of depression and fatigue during the treatment and survival stages of patients with colorectal cancer. Our findings indicate that health care professionals should provide appropriate nursing intervention to decrease depression and fatigue and enhance patient QoL.

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