scholarly journals Transcriptomic Changes of The Buccal Epithelium Exposed To Combustion Emissions of Smoky Coal in Xuanwei and Fuyuan, A Rural Region of China

2021 ◽  
Author(s):  
Qin Yang ◽  
Wancheng Guo ◽  
Hui Li
Keyword(s):  
Air Pollution ◽  
Molecular Mechanism ◽  
Indoor Air ◽  
Indoor Air Pollution ◽  
Buccal Epithelium ◽  
Rural Region ◽  
Incidence And Mortality ◽  
Combustion Emissions ◽  
Transcriptomic Changes ◽  
Smoky Coal

Abstract Indoor air pollution generated from solid fuels affects over half of the world's people. The smoky coal is one of the major sources of indoor air pollution and has been associated with the exceptionally high lung cancer incidence and mortality of non-smoking female residents in rural region Xuanwei and Fuyuan, China. Although some studies have characterized the etiology of the relationship between the smoky coal and the disease risk, the underlying molecular mechanism is still poorly understood. Thus we downloaded RNA sequence data (GSE64277) including 35 non-smoking female residents (26 smoky coal users and 9 smokeless coal users) of Xuanwei and Fuyuan, and conducted Gene Ontology Analysis, Kyoto Encyclopedia of Genes and Genomes Analysis and Weighted Gene Co-expression Network Analysis for transcriptomic changes in the buccal epithelium. The bioinformatics analysis of transcriptional data revealed that combustion emissions of smoky coal significantly altered the genes expression in the buccal epithelium. Activation of inflammation appeared to be a critical response and key risk factor in buccal epithelium associated with smoky coal-related indoor air pollution exposure. We identified 2318 differentially expressed genes, enriched-biological processes/cell components/pathways, gene co-expresssion relationships, 3 significant modules and 45 hub genes. This study contributes to understanding the uncovering molecular mechanism in the respiratory system that occurs with combustion emissions from smoky coal burning and carrying out potential effective interventions to prevent disease burdens.

AWARENESS ABOUT INDOOR AIR POLLUTION IN GENERAL POPULATION OF RAWALPINDI AND ISLAMABAD

2018 ◽  
Vol 8 (2) ◽  
pp. 80-83
Author(s):  
Nadia Tariq ◽  
Tamkeen Jaffry ◽  
Rahma Fiaz ◽  
Abdul Majid Rajput ◽  
Sadaf Khalid
Keyword(s):  
Air Pollution ◽  
General Population ◽  
Indoor Air ◽  
Indoor Air Pollution ◽  
Economic Status ◽  
Educational Status ◽  
Epidemiological Studies ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Significant Difference

Background: Indoor air pollutants are increasingly being associated with respiratory illnesses leading to high degree of morbidity and mortality. There are not sufficient epidemiological studies from Pakistan which assess level of awareness of indoor air pollution resulting in respiratory diseases in population. Methods: This cross sectional survey was carried out on general population of Rawalpindi/Islamabad. Sample size was 223 study subjects selected by non-probability convenient sampling. Knowledge of the study subjects was determined with regard to indoor air pollution, its effects on health and different sources of indoor air pollution with the help of a questionnaire. The influence of age, gender, educational status and socio economic status on the level of awareness was also analyzed. Results: Out of total 223 participants, 115 were males and108 females. Participants aware of indoor air pollution were 91.5% and adequate awareness about its sources was 80.7%. Those who knew indoor air pollution is detrimental to health were 95.1%. Awareness about building construction dust as source of indoor air pollution was maximum (84.8%). There was significant difference in awareness among participants with different monthly incomes and educational status and also between males and females. Conclusion: This study concludes that general population of Rawalpindi/Islamabad has fairly good awareness about sources of indoor air pollution. Use of harmful material causing indoor air pollution should be limited or substituted with better ones where possible.

ANALISIS PENGUKURAN KONSENTRASI KARBONMONOKSIDA (CO) PADA BREATHING ZONE PETUGAS PARKIR BASEMENT MALL KOTA BANDUNG

2019 ◽  
Author(s):  
Gede H Cahyana
Keyword(s):  
Air Pollution ◽  
Indoor Air ◽  
Indoor Air Pollution ◽  
Sampling Method ◽  
Breathing Zone ◽  
Gas Concentration ◽  
Average Value ◽  
Co Concentration ◽  
Personal Dosimeter ◽  
Co Gas

Indoor air pollution in closed room is one of the air pollution that gives serious threats to human health. One of them come from vehicle gas emissions in closed parking area. This research identifies and analyses CO concentration measured in Mall X parking man’s breathing zone with closed parking area and in Mall Y semi-opened parking area. CO measurement carried out by passive sampling method using Personal Dosimeter Tubes. Measurement result of CO gas concentration to parking man’s breathing zone in Mall X was 25 – 81,25 ppm with average value in 50 ± 26,15 ppm. Meanwhile CO gas concentration in Mall Y gave result 3,13 – 12,5 ppm with average value in 7,88 ± 4,36 ppm. Correlation value between CO concentration and its intake in Mall X area was 0,9983, meanwhile correlation value between CO concentration and its intake in Mall Y area was 0,9903. It was concluded that CO gas concentration measured in parking man’s breathing zone influenced the differences of CO intake value in significance value.

Environmentalists seek to set research agenda on indoor air pollution

BMJ ◽  
2011 ◽  
Vol 342 (may17 2) ◽  
pp. d3062-d3062 ◽  
Author(s):  
B. Roehr
Keyword(s):  
Air Pollution ◽  
Indoor Air ◽  
Research Agenda ◽  
Indoor Air Pollution

scholarly journals Is Indoor Air Pollution From Different Fuel Types Associated With the Anemia Status of Pregnant Women in Ethiopia?

2021 ◽  
Vol 12 ◽  
pp. 215013272110343
Author(s):  
Sewitemariam Desalegn Andarge ◽  
Abriham Sheferaw Areba ◽  
Robel Hussen Kabthymer ◽  
Miheret Tesfu Legesse ◽  
Girum Gebremeskel Kanno
Keyword(s):  
Air Pollution ◽  
Logistic Regression ◽  
Pregnant Women ◽  
Indoor Air ◽  
Pregnancy Outcomes ◽  
Indoor Air Pollution ◽  
Adverse Pregnancy Outcomes ◽  
Outcome Variable ◽  
Multivariable Logistic Regression Analysis ◽  
Adverse Pregnancy

Background Indoor air pollution from different fuel types has been linked with different adverse pregnancy outcomes. The study aimed to assess the link between indoor air pollution from different fuel types and anemia during pregnancy in Ethiopia. Method We have used the secondary data from the 2016 Ethiopian Demographic and Health Survey data. The anemia status of the pregnant women was the dichotomous outcome variable and the type of fuel used in the house was classified as high, medium, and low polluting fuels. Logistic regression was employed to determine the association between the exposure and outcome variables. Adjusted Odds Ratio was calculated at 95% Confidence Interval. Result The proportion of anemia in the low, medium, and high polluting fuel type users was 13.6%, 46%, 40.9% respectively. In the multivariable logistic regression analysis, the use of either kerosene or charcoal fuel types (AOR 4.6; 95% CI: 1.41-18.35) and being in the third trimester (AOR 1.72; 95% CI: 1.12-2.64) were significant factors associated with the anemia status of the pregnant women in Ethiopia. Conclusion According to our findings, the application of either kerosene or charcoal was associated with the anemia status during pregnancy in Ethiopia. An urgent intervention is needed to reduce the indoor air pollution that is associated with adverse pregnancy outcomes such as anemia.

Burning issues: tackling indoor air pollution

The Lancet ◽  
2011 ◽  
Vol 377 (9777) ◽  
pp. 1559-1560 ◽  
Author(s):  
Talha Khan Burki
Keyword(s):  
Air Pollution ◽  
Indoor Air ◽  
Indoor Air Pollution
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