scholarly journals Recurrence of Lymphedema and Related Characteristics in Discharged Breast Cancer Patients During The COVID-19 Pandemic: A Multicenter, Cross-Sectional Survey

2021 ◽  
Author(s):  
Xin PENG ◽  
Renwang Chen ◽  
Zhenli Rao ◽  
Yi Yang ◽  
Yunli Yan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Binary Logistic Regression ◽  
Anxiety And Depression ◽  
High Recurrence Rate ◽  
Breast Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Significant Difference ◽  
Severe Group

Abstract BackgroundTo evaluate recurrence of lymphedema and its influencing factors in discharged breast cancer patients with treated lymphedema during the COVID-19 pandemic and to propose feasible improvements. MethodsA multicenter, cross-sectional, hospital-based survey of discharged breast cancer patients was conducted during the COVID-19 pandemic in eight first-class hospitals in Wuhan city, China. Norman Questionnaire was used for assessing lymphedema, and multivariable binary logistic regression was performed to risk factors of moderate or severe lymphedema. Difference in living characteristics, anxiety and depression between no or mild group and moderate or severe group were compared. Preference in management of lymphedema were collected. Results 202 valid patients were included. 191 participants reported recurred lymphedema (prevalence: 94.6%, 95%CI 90.5% to 97.3%). 134 of them was mild and 57 were moderate/severe. In the 191 patients, the main symptom was swelling (140, 69.3%) and pain (56, 27.7%). Multivariable regression showed that age (odds ratio, 1.06, 95%CI: 1.02-1.10), radical surgery (OR=4.35, 95%CI: 1.54-12.50) and fully complete radiotherapy (OR=2.62, 95%CI: 1.17-5.87, P=0.019) was associated with the risk of moderate or severe lymphedema. No significant difference in lifestyles was observed but moderate or severe group experienced higher rate of anxiety and depression. patients preferred treatment in hospital and self-care at home equally.Conclusion The high recurrence rate of lymphedema in breast cancer patients with during COVID-19 should draw our great attention, continuous efforts should be made to identify patient at risk of lymphedema and distribute feasible guidance and education for self-management for these patients.

scholarly journals Effect of Flavor Enhancement on the Appreciation of Food in Breast Cancer Patients Undergoing Chemotherapy

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 320-320
Author(s):  
Kenza Drareni ◽  
Moustafa Bensafi ◽  
Helene Lusson ◽  
Damien Vansteene ◽  
Agnès Giboreau ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Hierarchical Cluster ◽  
Cross Sectional Study ◽  
Control Group ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Funding Sources ◽  
Significant Difference ◽  
The Impact

Abstract Objectives Given the influence of sensory signals on food intake regulation and the subsequent nutritional status, it is important to reduce the impact of commonly observed smell and taste alterations on the pleasure of eating during chemotherapy. This study aimed to examine the effect of various types of flavor enhancement on the appreciation of an appetizer by a group of patients undergoing chemotherapy. Methods Five eggplant appetizers with no seasoning (REF) or enhanced with either salt, lemon, garlic or cumin were developed. In this cross-sectional study, 36 healthy female subjects (age 58 ± 7 y) (control group) and 84 breast cancer patients (age 56 ± 11 y) treated with chemotherapy were recruited. A hierarchical cluster analysis based on patients' self-reported smell and taste abilities classified the patients in two groups: the ‘unaltered, (high sensory abilities) n = 49’ and the ‘altered, (poor sensory abilities), n = 35’ group. Participants tasted and assessed the appreciation of the reference appetizer on a visual analog scale and performed a randomized comparative liking task, by rating the appreciation for each flavor-enhanced appetizer relative to the REF (one-sample t-test). Results There was no significant difference in the appreciation of the REF appetizer between the three groups (P > 0.05). In the comparative liking task, the control group rated similarly the appreciation between the flavor-enhanced and the REF appetizers except for the cumin-enhanced appetizer, which was appreciated significantly more than the REF (P < 0.001). Patients in both ‘altered’ and ‘unaltered’ groups appreciated similarly the cumin appetizer (P > 0.05), more the salt and garlic-enhanced appetizers (P ≤ 0.001, P = 0.005, respectively) and significantly less the lemon-enhanced appetizer relative to the REF (P = 0.029), confirming a tendency for patients to reject acid-flavored foods. Conclusions The salt and garlic enhancements were appreciated by the patients independent of the stage of chemotherapy or the severity of smell and taste alterations. Flavor enhancement seems a good strategy to maintain the pleasure of eating in patients undergoing chemotherapy. Further research is still needed on the appreciation and intake of a complete meal (starter, main course, dessert). Funding Sources APICIL and ELIOR groups.

Pattern of Alternative Medicine Usage Among the Chinese Breast Cancer Patients: Implication for Service Integration

2003 ◽  
Vol 31 (04) ◽  
pp. 649-658 ◽  
Author(s):  
Abu S.M. Abdullah ◽  
Yvonne Lau ◽  
Louis W.C. Chow
Keyword(s):  
Breast Cancer ◽  
Alternative Medicine ◽  
Cancer Patients ◽  
Service Provision ◽  
Conventional Medicine ◽  
Breast Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Cancer Centers ◽  
Factors Associated

The study examined the pattern of and factors associated with use of alternative medicine (AM) among Chinese breast cancer patients. An analytical, cross-sectional survey of 352 breast cancer patients from two breast cancer centers was conducted in 1997. Amongst the respondents, the usage rate of alternative medicine was 27.8%. Factors forming the use of AM included being young to middle-aged, having higher education and a belief that AM would enhance orthodox treatment. A substantial proportion of Chinese breast cancer patients use AM besides conventional medicine. There is a need to integrate AM with conventional medicine to improve the service provision for cancer patients.

scholarly journals Clinical and genetic factors associated with anxiety and depression in breast cancer patients: a cross-sectional study

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Aline HAJJ ◽  
Roula HACHEM ◽  
Rita KHOURY ◽  
Souheil HALLIT ◽  
Bashar ElJEBBAWI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Sleep Quality ◽  
Cancer Patients ◽  
Genetic Factors ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
Breast Cancer Patients ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Despite the progress in assessment and treatment of breast cancer, being diagnosed with it or receiving chemotherapy treatment is still conceived as a traumatic experience. Women develop negative thoughts about life and death with detrimental effects on their daily physical functioning/activities, emotional state and overall quality of life. The aim of our study was to evaluate the level of anxiety and depression among breast cancer patients receiving chemotherapy and explore the correlation between these psychological disorders, clinical, sociodemographic and genetic factors. Methods A cross-sectional study was conducted among breast cancer patients undergoing intravenous chemotherapy at the oncology outpatient unit of Hôtel-Dieu de France hospital (November 2017–June 2019; Ethical approval number: CEHDF1016). All patients gave their written informed consent and completed several validated scales, including the Hospital Anxiety and Depression scale (HADS) for the assessment of anxiety and depression. Sleep quality, insomnia, cognitive function, fatigue and pain were also evaluated. Genotyping for certain gene polymorphisms (CLOCK, PER2, CRY2, OPRM1, ABCB1, COMT, DRD2) was performed using the Lightcycler® (Roche). Results A total of 112 women was included. The prevalence of depression was 43.4%, and 56.2% of the patients reported anxiety (based on the HADS classification). Multivariable analysis showed that higher cognitive scores and taking fosaprepitant were significantly associated with lower depression and anxiety scores. Moreover, being married compared to single was also associated with lower depression scores, whereas higher PSQI scores (worse sleep quality) and having the PER2 AA variant genotype compared to GG were significantly associated with higher depression scores. Finally, reporting a more severe insomnia and having the COMT Met/Met genotype were significantly associated with a higher anxiety score. Conclusions Our study demonstrated a strong relationship between depression scores and cognitive impairment, sleep quality, marital status, fosaprepitant intake, and PER2 polymorphism, while anxiety scores were correlated to cognitive impairment, insomnia severity, fosaprepitant intake, and COMT polymorphism. The association with PER polymorphism was not previously reported. Identification of genetic and clinical risk factors for anxiety and depression would help clinicians implement an individualized management therapy aiming at preventing and alleviating the burden of these symptoms in breast cancer patients, hence improving their overall quality of life.

scholarly journals Discharge of breast cancer patients to primary care at the end of hospital follow-up: A cross-sectional survey

2013 ◽  
Vol 49 (8) ◽  
pp. 1836-1844 ◽  
Author(s):  
Carriene Roorda ◽  
Annette J. Berendsen ◽  
Manon Haverkamp ◽  
Klaas van der Meer ◽  
Geertruida H. de Bock
Keyword(s):  
Breast Cancer ◽  
Primary Care ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional

scholarly journals A cross-sectional survey of the diagnosis and management of bone metastasis in breast cancer patients in Turkey

2014 ◽  
Vol 22 (10) ◽  
pp. 2629-2634 ◽  
Author(s):  
Ali Arican ◽  
Tulin Bozkurt ◽  
Hakan Bozcuk ◽  
Binnaz Demirkan ◽  
Suleyman Buyukberber ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Metastasis ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Diagnosis And Management

scholarly journals MMP-2 levels evaluation and their relationship with breast cancer progression.

2020 ◽  
Vol 27 (02) ◽  
pp. 424-430
Author(s):  
Ifrah Yaqoob ◽  
Muhammad Saeed ◽  
Aysha Azhar
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Invasive Ductal Carcinoma ◽  
Cancer Progression ◽  
Ductal Carcinoma ◽  
Histological Type ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Significant Difference ◽  
The University

Matrix metalloproteinases (MMPs) play significant part in the tumor development, metastasis and invasion by proteolytic degradation of basement membrane and extracellular matrix. Hence MMPs can serve as good biomarkers for carcinoma breast particularly MMP-2 in our population. Objectives: To measure the concentrations of MMP-2 in plasma of breast cancer patients and establishing their correlation with stage and grade of the disease. Study Design: Comparative cross sectional. Setting: Surgery department Madinah Teaching Hospital (MTH) and the Pathology department, The University of Faisalabad (TUF), Faisalabad. Period: 1st August, 2017 to 31st December, 2017. Material & Methods: Only females with diagnosed breast cancer disease along with staging and grading were included in the study. Females with incomplete reports, on chemotherapy or radiotherapy or having other diseases like oral squamous cell carcinoma, rheumatoid arthritis etc were excluded. ELISA kit was applied to measure the concentrations of MMP-2 in plasma of the participants. OD values were calculated at 450 nm by ELISA reader placed at Post Graduate Research Laboratory, The University of Faisalabad, Faisalabad. Data was gathered and results were finalized by using SPSS 22 for statistical assessment. Results: Age of 64(72%) breast cancer patients was within range of 30-76yrs and age for 25(28%) healthy females as controls range was 18-70yrs. Difference between ages of cases and controls using t-test was statistically highly significant. Ninety five percent cases showed invasive ductal carcinoma (IDC) as histological type. Range of MMP-2 levels in cases was 80-690 ng/mL with mean 451.02 while range of MMP-2 levels in controls was 65-830ng/mL with mean 329.72 showing statistically significant difference. Relationship of different groups of MMP-2 levels in cases with stages of breast cancer was established using chi-square test which was statistically significant, stage IIB (37.5%) and IIIA (34.4%) tumors showed higher values of MMP-2. Relationship between MMP-2 levels, grade, tumor size and node invasion was nonsignificant statistically. Conclusion: MMP-2 levels were raised in cases in comparison to healthy controls. Age of majority patients was > 45 yrs while the invasive ductal carcinoma was the main histological type. MMP-2 levels were associated with stage of the disease.

scholarly journals IMPACT OF CANCER ON QUALITY OF LIFE & DEPRESSION AMONG CAREGIVERS

2022 ◽  
Vol 71 (6) ◽  
pp. 2216-19
Author(s):  
Mahwash Zulfiqar Khan ◽  
Nusrat Qamar ◽  
Shahbaz Ahmad ◽  
AbuBakar Siddique
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Negative Impact ◽  
Breast Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Female Cancer Patients ◽  
The Impact

Objective: To determine the impact of cancer on quality of life and depression among caregivers. Study Design: Cross-sectional survey. Place and Duration of Study: Anmol Hospital, Lahore, from Jul 2019 to Jan 2020. Methodology: Data collected from caregivers of female cancer patients by purposive sampling technique using Standardized Questionnaire of Caregiver Assistance Scale and emotional distress was assessed by the Profile of Mood States. Data were entered into Statistical Package for Social Sciences for statistical analysis. Results: Among 110 participants (caregivers of female cancer patients) 28 (25.5%) were female while 82 (74.5%) were male caregivers. Patients other than breast cancer were 79 (71.8%), while breast cancer patients were 31 (28.2%). There was a significant association between caregiver health, quality of life and level of depression, one year ago, and at current with p-values= 0.001, 0.001 and 0.01 respectively. Conclusion: There was a negative impact on the health and quality of life of caregivers. Their health was better in the beginning but with time, their lives became more difficult.

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