Anxiety and Depression in Glaucoma Patients and its Correlations with Vision-related Quality of Life and Objective Visual Function Indices

Psychological Disorders ◽

Anxiety And Depression ◽

Partial Regression ◽

Related Quality

Abstract Background: To investigate anxiety and depression in glaucoma patients and its correlations with vision-related quality of life (VR-QoL) and objective visual function indices.Methods: In this cross-sectional study, the Hospital Anxiety and Depression Scale (HADS) and the 25-item National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) questionnaires were administered to 446 Chinese glaucoma patients to assess their psychological disorders, namely anxiety and depression, and VR-QoL, respectively. Socio-demographic and clinical data were collected at the same time. Multivariate linear regression analysis was carried out to investigate the associations between VR-QoL, visual function indices and psychological disorders. Standardized partial regression analysis was used to identify the variable mostly indicative in evaluating psychological burdens. Results: The prevalence of anxiety and depression in Chinese glaucoma patients was 12.11% and 25.78%, respectively. Most of the subscales and the composite score of NEI VFQ-25 were negatively associated with each of anxiety and depression after adjusting for socio-demographic and clinical variables. For visual function indices, only the best corrected visual acuity of both eyes was correlated with anxiety after adjustment. Standardized partial regression analysis further showed VR-QoL but not the objective visual function indices mostly relevant to psychological disturbances. Conclusions: Anxiety and depression were common in Chinese glaucoma patients. Self-reported VR-QoL was beneficial in assessing glaucoma patients’ psychological disorders, while objective visual function indices provide little hint on it.

Health-Related Quality of Life in Stroke Survivors in Relation to the Type of Inpatient Rehabilitation in Serbia: A Prospective Cohort Study

Medicina ◽

10.3390/medicina56120666 ◽

2020 ◽

Vol 56 (12) ◽

pp. 666

Author(s):

Natasa K. Rancic ◽

Milan N. Mandic ◽

Biljana N. Kocic ◽

Dejan R. Veljkovic ◽

Ilija D. Kocic ◽

...

Keyword(s):

Quality Of Life ◽

Regression Analysis ◽

Inpatient Rehabilitation ◽

Stroke Survivors ◽

Health Related Quality ◽

Related Quality ◽

Background and objectives: Health-related quality of life after stroke is an important public health issue. The objective of the study was to investigate the relationship between the perceived health-related quality of life in stroke survivors in relation to the type of inpatient rehabilitation. Materials and Methods: Using a random selection method out of a total of 688 patients, every fourth survivor who had a stroke in the period from 1 January 2017 to 31 December 2019 was selected from the admission protocol of the Clinic for Rehabilitation and Physical Medicine of the Clinical Centre Niš, Serbia. A total of 160 first-ever stroke survivors were included (80 underwent additional inpatient rehabilitation and 80 underwent only inpatient rehabilitation in a tertiary health institution) in a twelve-month prospective study. The EuroQuol-5 Dimension (EQ5D) questionnaire and Stroke Impact Scale were used for the assessment. Multivariate linear regression analysis was done. Results: Multivariate linear regression analysis showed that additional inpatient rehabilitation from six up to eight weeks after discharge was significantly associated with better self-reported health condition by 3.9 times (from 1.9 to 8.2), significantly decreased the ranks of EQ5D by 1.78 times (from 1.02 to 3.11), and showed a higher health-related quality of life. We determined a significant increase of strength, emotions, mobility, and participation role in survivors who underwent additional inpatient rehabilitation compared with those who did not. Conclusions: There was a significant difference in health-related quality of life perceived by stroke survivors who underwent additional hospital rehabilitation in relation to those who underwent only inpatient rehabilitation.

Determinants of health-related quality of life in colon cancer patients include stoma and smoking habits, but not type of surgery

10.21203/rs.2.13676/v1 ◽

2019 ◽

Author(s):

Catarina Tiselius ◽

Andreas Rosenblad ◽

Eva Strand ◽

Kennet Smedh

Keyword(s):

Quality Of Life ◽

Colon Cancer ◽

Regression Analysis ◽

Cancer Patients ◽

Health Related Quality ◽

Related Quality ◽

Abstract Background: Health-related quality of life (HRQoL) has gained increased attention in cancer care. Studies have shown that poor QoL might worsen the cancer related prognosis. The aim of this study was to investigate HRQoL in patients with colon cancer and to compare data with reference values from the general population in Sweden at diagnosis (baseline) and at six months of follow-up. Methods : This was a prospective population-based study of colon cancer patients from Västmanland County, Sweden, included between March 2012 and September 2016. HRQoL was measured using the cancer-specific EORTC QLQ-C30 questionnaire. Data on HRQoL was compared with Swedish population reference values. Multiple linear regression analysis adjusted for age, sex, body mass index (BMI), American Society of Anaesthesiology (ASA) physical status classification, emergency/elective surgery, and resection with/without a stoma and tumour stage (TNM), was used. Results : A total of 67% (376/561) of all incident colon cancer patients (196 [52.1%] females) were included. Mean (range) age was 73 (30-96) years. The univariate analysis showed that patients with colon cancer had worse QoL (8/15 parameters) compared with a Swedish reference population both at baseline and at 6 months follow-up. Furthermore, linear regression analysis showed that patients with more comorbidity (ASA 3 and 4), smokers and patients planned to be operated on with a stoma, were at higher risks for poor QoL than the other included patients. Conclusions : The reported determinants of HRQoL may be used to identify risk groups and enable individualized care for patients that need more support from health care.

Adherence to COVID-19 Preventive Measures among Dental Care Workers in Vietnam: An Online Cross-Sectional Survey

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph19010481 ◽

2022 ◽

Vol 19 (1) ◽

pp. 481

Author(s):

Tai Tan Tran ◽

Thang Van Vo ◽

Tuyen Dinh Hoang ◽

Minh Vu Hoang ◽

Nhu Thi Quynh Tran ◽

...

Keyword(s):

Quality Of Life ◽

Regression Analysis ◽

Dental Care ◽

Preventive Measures ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Care Workers

An online cross-sectional survey using a “snowball” sampling method was carried out to assess the adherence to COVID-19 preventive measures among dental care workers (DCWs) during the pandemic. Six questions concerning the COVID-19 preventive guidelines issued by the Vietnam Ministry of Health were used to evaluate DCWs’ adherence to preventive measures at dental care clinics. The quality of life of DCWs was assessed using the WHO-5 questionnaire and was defined as low if the total score was less than 13 points. Factors relating to adherence to COVID-19 prevention measures of DCWs were determined by multivariate linear regression analysis. In total, 514 DCWs completed the questionnaire. A total of 37% DCWs rated their quality of life as low. Regression analysis suggested that older age, a better quality of life, living in an urban area, and training on COVID-19 prevention were associated with better adherence to COVID-19 preventive measures, while being a dentist and lack of personal protective equipment was associated with less adherence to COVID-19 preventive measures. The pandemic had a significant negative impact on the physical and mental health of DCWs. Therefore, specific national guidelines for the prevention and control of the spread of COVID-19 in dental facilities should be issued.

Effects of depression and exercise on health-related quality of life in patients with Parkinson's disease

Chronic Illness ◽

10.1177/1742395318796166 ◽

2018 ◽

Vol 16 (3) ◽

pp. 190-200

Author(s):

George W Koutsouras ◽

Kimberly Levine ◽

Nathalie Duroseau ◽

Christina Ciraco ◽

Vivian Chan ◽

...

Keyword(s):

Quality Of Life ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Depression Scale ◽

Health Related Quality ◽

Related Quality ◽

Objectives There is limited literature describing the effect exercise may have on depression and an individual’s health-related quality of life (HRQoL) in Parkinson’s Disease (PD). We aim to quantify this effect. Methods A cross-sectional questionnaire was administered to 60 PD subjects. The Parkinson’s Disease Questionnaire-39 (PDQ-39) summary index and the Geriatric Depression Scale-30 were used to quantify HRQoL and depression, respectively. Data were obtained on exercise habits. ANOVA and multivariate linear regression analysis were used to calculate mean differences in HRQoL. Results Depression was consistently related to HRQoL ( p < 0.05). Of those who exercised as an adult before PD diagnosis, 49.02% ( n = 25) reported depression as compared to 88.89% ( n = 8) of those who did not report adult exercise ( p = 0.03). Those who exercised frequently as an adult prior to PD diagnosis had a better PDQ-39 Cognitive Index ( p = 0.03). Those who were not depressed and were currently exercising had a significantly higher HRQoL than those who were depressed and did not exercise ( p < 0.01). Discussion Exercising and depression may interact to affect HRQoL. Thus, coordination of mental health evaluation and exercise regimens in persons with PD may improve HRQoL.

The Relative Influence of Surgical Disease and Co-Morbidities on Patient Responses to a Generic Health-Related Quality-of-Life Instrument

The American Surgeon ◽

10.1177/000313480907501112 ◽

2009 ◽

Vol 75 (11) ◽

pp. 1084-1090

Author(s):

Emily France ◽

Vic Velanovich

Keyword(s):

Quality Of Life ◽

Regression Analysis ◽

Linear Regression ◽

Health Related Quality ◽

Surgical Disease ◽

Sf 36 ◽

Related Quality ◽

Generic health-related quality-of-life (QoL) instruments are increasingly used to assess the outcomes of surgical interventions. However, it is unclear to what extent the patient's associated comorbidities have on the responsiveness of these instruments to measure changes caused by the operation. The purpose of this study was to assess the relative influence of comorbidities to surgical disease in how patients answered the items of the most frequently used generic instrument, the SF-36. Sixty-nine preoperative patients completed the SF-36, which contains 36 items covering eight domains and a health transition question. For each of the 36 items, patients were asked to rate the influence of their surgical disease and their comorbidities on how they answered the items from 1 to 10. The surgical disease, comorbidities, and medications were recorded. Data was analyzed using the Mann-Whitney U test and linear regression analysis. Of the 36 items of the SF-36, patients reported that their surgical disease influences nine items greater than their comorbidities (P < 0.05). Using linear regression analysis, the number of comorbidities did not effect the influence of the surgical disease in any item; however, this number had a direct relationship (P < 0.05) with the influence of comorbidities on how the patient answered the item. However, the magnitude of the influence was low. There was an inverse (negative slope, P < 0.05) relationship between the number of comorbidities and the score of six of eight domains. Although the surgical disease has more of an influence on how patients answered the items of the SF-36, as the number of comorbidities increased, these seem to have more influence. Therefore, the SF-36 would be a good choice for assessing QoL in most surgical disease. However, as the overall magnitude of this influence was low, this may be a cause of the lack of responsiveness of generic QoL instruments in measuring the effect of operations on QoL. Importantly, as the number of comorbidities increased, the scores of the SF-36 decreased, implying that the effect of the surgical disease would be greater in patients with fewer comorbidities.

Adherence to COVID-19 preventive measures among dental care workers in Vietnam: an online cross-sectional survey

10.21203/rs.3.rs-1160815/v1 ◽

2021 ◽

Author(s):

Tai Tan Tran ◽

Thang Van Vo ◽

Tuyen Dinh Hoang ◽

Minh Vu Hoang ◽

Nhu Thi Quynh Tran ◽

...

Keyword(s):

Quality Of Life ◽

Regression Analysis ◽

Dental Care ◽

Preventive Measures ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Care Workers

Abstract An online cross-sectional survey using a "snowball" sampling method was carried out to assess the adherence to COVID-19 preventive measures among dental care workers (DCWs) during the pandemic. Six questions concerning the COVID-19 preventive guidelines issued by the Vietnam Ministry of Health were used to evaluate DCWs adherence to preventive measures at dental care clinics. The quality of life of DCWs was assessed using the WHO-5 questionnaire and was defined as low if the total score was less than 13 points. Factors relating to adherence to COVID-19 prevention measures of DCWs were determined by multivariate linear regression analysis. In total, 514 DCWs completed the questionnaire. 37% DCWs rated their quality of life as low. Regression analysis suggested that older age, better quality of life, living in an urban area, and training on COVID-19 prevention were associated with better adherence to COVID-19 preventive measures, while being a dentist and lack of personal protective equipment was associated with less adherence to COVID-19 preventive measures. The pandemic had a significant negative impact on the physical and mental health of DCWs. Therefore, specific national guidelines for the prevention and control of the spread of COVID-19 in dental facilities should be issued.

The Impact of Sarcopenic Obesity on Health-Related Quality of Life of Treatment-Seeking Patients with Obesity

Current Diabetes Reviews ◽

10.2174/1573399816666200211102057 ◽

2020 ◽

Vol 16 (6) ◽

pp. 635-640 ◽

Cited By ~ 1

Author(s):

Leila Itani ◽

Dima Kreidieh ◽

Dana El Masri ◽

Hana Tannir ◽

Marwan El Ghoch

Keyword(s):

Quality Of Life ◽

Regression Analysis ◽

Weight Management ◽

Sarcopenic Obesity ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

The Impact

Background: There is a paucity of studies on health-related quality of life (HRQoL) and sarcopenic obesity (SO). Objective: This study aimed to assess the potential association between SO and impaired HRQoL. Methods: The ORWELL 97 questionnaire was used to assess HRQoL and body composition was measured using a bioimpedance analyser (Tanita BC-418) in 130 patients with obesity, referred to the Nutritional and Weight Management outpatient clinic of Beirut Arab University in Lebanon. Participants were then categorized on the basis of the absence or presence of SO. Results: Sixty-four of the 130 participants met the criteria for SO (49.2%) and displayed significantly higher total ORWELL 97 scores than those in the group without SO (64.00 vs. 41.00, p=0.001), indicative of poorer HRQoL. Linear regression analysis showed that SO was associated with an increase in ORWELL 97 scores by nearly 24 units (β=24.35, 95% CI=11.45-37.26; p<0.0001). Moreover, the logistic regression analysis showed that SO increased the odds of clinically significant impairment of HRQoL (ORWELL 97 score ≥74.25) by nearly seven-fold (OR=7.37, 95% CI=1.92-28.39; p=0.004). Conclusion: Our findings show that the presence of SO was associated with increased impairment of HRQoL that reaches clinical significance when compared to obesity only. Future studies are needed to clarify whether this may influence clinical outcomes. If this is shown to be the case, weight management programs should incorporate additional strategies to improve HRQoL in individuals with SO.

Patient-reported outcomes of occipitocervical and atlantoaxial fusions in children

Journal of Neurosurgery Pediatrics ◽

10.3171/2016.8.peds16286 ◽

2017 ◽

Vol 19 (1) ◽

pp. 85-90 ◽

Cited By ~ 4

Author(s):

Aditya Vedantam ◽

Daniel Hansen ◽

Valentina Briceño ◽

Alison Brayton ◽

Andrew Jea

Keyword(s):

Quality Of Life ◽

Regression Analysis ◽

Patient Reported Outcomes ◽

Pediatric Patients ◽

Atlantoaxial Fusion ◽

Patient Reported

OBJECTIVE There is limited literature on patient-reported outcomes (PROs) and health-related quality of life (HRQOL) outcomes in pediatric patients undergoing surgery for craniovertebral junction pathology. The aim of the present study was to assess surgical and quality of life outcomes in children who had undergone occipitocervical or atlantoaxial fusion. METHODS The authors retrospectively reviewed the demographics, procedural data, and outcomes of 77 consecutive pediatric patients who underwent posterior occipitocervical or atlantoaxial fusion between 2008 and 2015 at Texas Children's Hospital. Outcome measures (collected at last follow-up) included mortality, neurological improvement, complications, Scoliosis Research Society Outcomes Measure–22 (SRS-22) score, SF-36 score, Neck Disability Index (NDI), and Pediatric Quality of Life Inventory (PedsQL). Multivariate linear regression analysis was performed to identify factors affecting PROs and HRQOL scores at follow-up. RESULTS The average age in this series was 10.6 ± 4.5 years. The median follow-up was 13.9 months (range 0.5–121.5 months). Sixty-three patients (81.8%) were treated with occipitocervical fusion, and 14 patients (18.1%) were treated with atlantoaxial fusion. The American Spinal Injury Association (ASIA) grade at discharge was unchanged in 73 patients (94.8%). The average PRO metrics at the time of last follow-up were as follows: SRS-22 score, 4.2 ± 0.8; NDI, 3.0 ± 2.6; the parent's PedsQL (ParentPedsQL) score, 69.6 ± 22.7, and child's PedsQL score, 75.5 ± 18.7. Multivariate linear regression analysis revealed that older age at surgery was significantly associated with lower SRS-22 scores at follow-up (B = −0.06, p = 0.03), and the presence of comorbidities was associated with poorer ParentPedsQL scores at follow-up (B = −19.68, p = 0.03). CONCLUSIONS This study indicates that occipitocervical and atlantoaxial fusions in children preserve neurological function and are associated with acceptable PROs and ParentPedsQL scores, considering the serious nature and potential for morbidity in this patient population. However, longer follow-up and disease-specific scales are necessary to fully elucidate the impact of occipitocervical and atlantoaxial fusions on children.