Effects of Satureja Edmondi Briq on Ameliorate Reproductive Parameters in Pentylenetetrazol-Induced Epilepsy Models in Rats

Reproductive Potential ◽

Sperm Parameters ◽

Male Rats ◽

World Health ◽

Health Organization ◽

Abstract BackgroundEpilepsy is one of the common neurological brain defects that causes unpredictable, recurrent seizures. It has adverse effects on the reproductive functions.Oxidative stress contributes to the evolution of epilepsy, including reduction of sperm count and motility,increase of abnormal sperm morphology, and low testosterone.Antioxidants are beneficial to spermatogenesis and sperm parameters. Satureja edmondiBriq is known as a powerful antioxidant that can reduce the effects of oxidative stress. The aim of this study was to evaluate the effects of Satureja edmondion reproductive potential in pentylenetetrazol (PTZ)-induced epileptic male rats.MethodsIn this experimental study, 48 Wistar male rats with an average age of 10 weeks and weightof 240- 260g were used. Animals were randomized into normal and kindled groups that were treated with different doses of S.edmondi essential oil. Treatment of animals lasted 4 weeks. In the end, testosterone, follicle-stimulating hormone, luteinizing hormone, and sperm parameters were measured according to the World Health Organization (WHO) standards.ResultsThis study showed that all sperm parameters,including sperm count, sperm viability, and progressive sperm motility were increased and testosterone, follicle-stimulating hormone and luteinizing hormone (FSH,LH) changes in the epileptic and normal groups were changed with an increase in the dose of S.edmondi essential oil. ConclutionsThe changes were significant in some parameters. S.edmondi as a good source of antioxidants can improve sperm parameters and reproductive potential in PTZ-induced epileptic male rats.

Prolactin Releasing Peptide (PrRP) Stimulates Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) via a Hypothalamic Mechanism in Male Rats

Endocrinology ◽

10.1210/endo.141.5.7528 ◽

2000 ◽

Vol 141 (5) ◽

pp. 1909-1912 ◽

Cited By ~ 43

Author(s):

L. J. Seal ◽

C. J. Small ◽

M. S. Kim ◽

S. A. Stanley ◽

S. Taheri ◽

...

Keyword(s):

Luteinizing Hormone ◽

Male Rats ◽

Prolactin Releasing Peptide ◽

Hypothalamic Mechanism ◽

P-232. Ovulation induction with recombinant human follicle stimulating hormone: a conventional slow protocol compared with a step-down protocol in anovulatory women (World Health Organization group II)

Human Reproduction ◽

10.1093/humrep/14.suppl_3.257-a ◽

1999 ◽

Vol 14 (Suppl_3) ◽

pp. 257-257

Author(s):

J. Hernandez ◽

M.J. Inarra ◽

E. Campeny ◽

C. Salvador ◽

G. Manzanera

Keyword(s):

World Health Organization ◽

Ovulation Induction ◽

World Health ◽

Step Down ◽

Group Ii ◽

Health Organization ◽

O-230. Comparison of recombinant and urinary follicle stimulating hormone preparations efficiency for achievement of follicular selection in patients with chronic anovulation (World Health Organization group II)

Human Reproduction ◽

10.1093/humrep/14.suppl_3.127-a ◽

1999 ◽

Vol 14 (Suppl_3) ◽

pp. 127-128

Author(s):

J.N. Hugues ◽

I. Cedrin-Durnerin ◽

B. Bstandig ◽

M. Blasquez ◽

F. Hervé ◽

...

Keyword(s):

World Health Organization ◽

World Health ◽

Group Ii ◽

Health Organization ◽

Follicular Selection ◽

EFFECTS OF FOLLICLE-STIMULATING HORMONE AND LUTEINIZING HORMONE ON PLASMA TESTOSTERONE LEVELS IN HYPOPHYSECTOMIZED AND IN INTACT IMMATURE AND ADULT MALE RATS

Journal of Endocrinology ◽

10.1677/joe.0.0610193 ◽

1974 ◽

Vol 61 (2) ◽

pp. 193-198 ◽

Cited By ~ 14

Author(s):

S. EL SAFOURY ◽

A. BARTKE

Keyword(s):

Luteinizing Hormone ◽

Adult Male ◽

Seminal Vesicles ◽

Male Rats ◽

Plasma Testosterone ◽

Adult Rats ◽

Testosterone Levels ◽

Hypophysectomized Rats ◽

SUMMARY The effects of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) on plasma testosterone levels were examined in hypophysectomized and in intact immature and adult male rats. The animals were injected with saline, LH, FSH, or both gonadotrophins twice daily for 3·5 days and were killed 3 h after the last injection. Plasma testosterone levels were measured by radioimmunoassay. In immature hypophysectomized rats, plasma testosterone levels were not changed by treatment with LH, FSH or LH plus FSH. The weight of the testes and of the seminal vesicles was increased only in animals injected with both LH and FSH. In adult hypophysectomized rats, LH caused the expected increase in plasma testosterone levels, while FSH injected alone had no effect. Plasma testosterone levels in rats treated with 5 μg LH and 20 μg FSH were significantly greater than those in animals given 5 μg LH alone. However, the same dose of FSH did not potentiate the action of 25 μg LH on plasma testosterone levels. In adult hypophysectomized rats the weight of testes was not affected by any of the treatments. The weight of the seminal vesicles was increased by the higher dose of LH and addition of FSH caused no further increase. In intact immature and adult rats plasma testosterone levels and the weight of testes were not changed by any of the treatments. Seminal vesicle weight was increased only in adult rats treated with the higher dose of LH together with FSH. The results demonstrate that FSH potentiates the action of low doses of LH on plasma testosterone levels in adult hypophysectomized rats and suggest that FSH may be involved in the regulation of androgen secretion by the rat testis.

Follicle-stimulating hormone receptor polymorphism affects the outcome of ovulation induction in normogonadotropic (World Health Organization class 2) anovulatory subfertility

Fertility and Sterility ◽

10.1016/j.fertnstert.2015.01.002 ◽

2015 ◽

Vol 103 (4) ◽

pp. 1081-1088.e3 ◽

Cited By ~ 13

Author(s):

Olivier Valkenburg ◽

Evert J.P. van Santbrink ◽

Tamar E. König ◽

Axel P.N. Themmen ◽

André G. Uitterlinden ◽

...

Keyword(s):

World Health Organization ◽

Hormone Receptor ◽

Ovulation Induction ◽

World Health ◽

Health Organization ◽

Receptor Polymorphism ◽

Effect of Active and Passive Immunization with Luteinizing Hormone-Releasing Hormone on Serum LuteinizingHormone and Follicle-Stimulating Hormone Levels nd the Ultrastructure of the Pituitary Gonadotrophs in Castrated Male Rats

Endocrinology ◽

10.1210/endo-99-1-291 ◽

1976 ◽

Vol 99 (1) ◽

pp. 291-303 ◽

Cited By ~ 27

Author(s):

A. ARIMURA ◽

M. SHINO ◽

K. G. DE LA CRUZ ◽

E. G. RENNELS ◽

A. V. SCHALLY

Keyword(s):

Luteinizing Hormone ◽

Passive Immunization ◽

Male Rats ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone ◽

Hormone Levels ◽

A Quantitative Immunocytochemical Study of the Luteinizing Hormone and Follicle-Stimulating Hormone Cells in the Adenohypophysis of Adult Male Rats and Adult Female Rats throughout the Estrous Cycle*

Endocrinology ◽

10.1210/endo-113-3-970 ◽

1983 ◽

Vol 113 (3) ◽

pp. 970-984 ◽

Cited By ~ 37

Author(s):

M. O. DADA ◽

G. T. CAMPBELL ◽

C. A. BLAKE

Keyword(s):

Luteinizing Hormone ◽

Estrous Cycle ◽

Adult Female ◽

Adult Male ◽

Female Rats ◽

Male Rats ◽

Immunocytochemical Study ◽

Comparison of mice’ sperm parameters exposed to some hazardous physical agents

Environmental Analysis Health and Toxicology ◽

10.5620/eaht.2021013 ◽

2021 ◽

Vol 36 (3) ◽

pp. e2021013

Author(s):

Mohammad-Bagher Abdollahi ◽

Somayeh Farhang Dehghan ◽

Faezeh Abasi Balochkhaneh ◽

Manouchehr Ahmadi Moghadam ◽

Hamzeh Mohammadi

Keyword(s):

Sperm Count ◽

Semen Analysis ◽

Field Studies ◽

Sperm Parameters ◽

World Health ◽

Control Group ◽

Normal Morphology ◽

Progressive Motility ◽

Noise Vibration ◽

Health Organization

The present study was aimed to compare the effects of exposure to noise, vibration, lighting, and microwave on male mice’ sperm parameters. The mice were randomly assigned to five groups of eight, which comprised of the unexposed group and exposure groups including the lighting (1000 lux), noise (100 dB(A)), vibration (acceleration of 1.2 m/s2) and microwave (power density of 5 watts). The exposure groups were subjected to the four agents for 8 hours a day, 5 days a week during a 2-week period. Semen analysis were done according to World Health Organization guidelines. The highest significant mean difference in sperm count (-1.35×106/mL) had being observed between the microwave group and the control one (P=0.001). The highest difference in immotile percent (25.88 %) had being observed between the noise group and the control one (P=0.001). The highest difference in normal morphology (-27.06 %) observed between the lighting exposure group and the control group (P=0.001). The four agents can cause changes in different sperm parameters, however for definite conclusion; more laboratory and field studies are required. In total, exposure to microwave has had the greatest effect on sperm count and exposure to light has had the greatest effect on normal morphology and non-progressive motility. Moreover, exposure to noise has had the greatest effect on progressive motility and immotile percent, respectively.