scholarly journals Role of Mammography and Ultrasound in the Evaluation of Palpable Breast Masses with Histopathological Correlation

Author(s):  
Sudhakar Kanumuri ◽  
Kada Venkata Ramana ◽  
Sudhir Sachar
Author(s):  
Shyam Chhadi ◽  
Tulsi Chhadi ◽  
Kamlesh Bagde

Background: Breast cancer is the most frequently diagnosed cancer amongst women worldwide. Ultrasound elastography is a non-invasive method for determining tissue mechanical properties and seems to be compensating for the deficiencies of conventional USG. We aimed to evaluate the sensitivity and specificity of ultrasound elastography in detection and characterization of various breast masses and study its role in differentiating benign and malignant breast masses with FNAC and/or histopathological correlation.Methods: A total of 126 patients with breast lesions confirmed on USG were enrolled for the study, out of which 10 were lost to follow-up and excluded. Consecutive patients presenting with palpable breast lesions were assessed with conventional B-mode USG. Those confirmed to have breast lesion were then assessed with Strain Elastography (SE). FNAC was used for histopathological confirmation of malignant lesions. The benign lesions were diagnosed by a combination of FNAC and biopsy and were followed up for 6 months.Results: There were 56 (48.3%) malignant and 60 (51.7%) benign lesions. A sensitivity of 83.9% and a specificity of 91.7% was obtained for elasticity score when cut-off value of 3.5 was used (area under the curve- 0.924, 95% CI- 0.869 to 0.979, p-0.0001). Sensitivity of 91.1% and specificity of 88.3% was obtained for SR scores, when a cut off of 2.94 was used (area under the curve- 0.969, 95% CI- 0.943-0.995, p-0.0001). The Pearson correlation coefficient for elasticity scores and SR values was 0.936, indicating very good agreement (correlation) between the two methods.Conclusions: Ultrasound elastography is a simple and rapid method that can improve the sensitivity and specificity of USG and can decrease the rate of unnecessary biopsies.


2014 ◽  
Vol 56 (3) ◽  
pp. 292-295
Author(s):  
Mahmood H. Hassan ◽  
◽  
Ahmed R. Hizam ◽  
Safa M. Al-Obaidi ◽  
◽  
...  

2016 ◽  
Vol 57 (2) ◽  
pp. 77 ◽  
Author(s):  
AkinFirat Kocaay ◽  
SuleymanUtku Celik ◽  
Yusuf Sevim ◽  
Sefa Ozyazici ◽  
OmerArda Cetinkaya ◽  
...  

2016 ◽  
Vol 73 (3) ◽  
pp. 239-245 ◽  
Author(s):  
Aleksandar Dobrosavljevic ◽  
Snezana Rakic ◽  
Branka Nikolic ◽  
Svetlana Jankovic-Raznatovic ◽  
Svetlana Dragojevic-Dikic ◽  
...  

Background/Aim. Not only that ultrasound makes the difference between cystic and solid changes in breast tissue, as it was the case at the beginning of its use, but it also makes the differential diagnosis in terms of benign-malignant. The aim of this study was to assess the role of sonography in the diagnosis of palpable breast masses according to the American College of Radiology Ultrasonographic Breast Imaging Reporting and Data System (BI-RADS) and to correlate the BI-RADS 4 and BI-RADS 5 category with pathohistological findings. Methods. A retrospective study was conducted with the breast sonograms of 30 women presented with palpable breast masses found to be mammography category BI-RADS 0 and ultrasonographic BI-RADS categories 4 and 5. The sonographic categories were correlated with pathohistological findings. Results. Surgical biopsy in 30 masses revealed: malignancy (56.7%), fibroadenoma (26.7%), fibrocystic dysplasia with/without atypia (10%), lipoma (3.3%) and intramammary lymph node (3.3%). Correlation between BI-RADS categories and pathohistological findings was found (p < 0.05). All BI-RADS 5 masses were malignant, while in BI-RADS 4A category fibroadenomas dominated. A total of 53.8% of all benign lesions were found in women 49 years of age or younger as compared with 35.3% of all malignancies in this group (p < 0.05). Conclusion. Ultrasonography BI-RADS improved classification of breast masses. The ultrasound BI-RADS 4 (A, B, C) and BI-RADS 5 lesions should be worked-up with biopsy.


2020 ◽  
pp. 1-2
Author(s):  
Vamshi Deepak Gudipati ◽  
Radhika Mucharla ◽  
Rammohan Peddi ◽  
K.Devender Reddy

Introduction – FNAC has become increasingly popular in diagnosis of palpable breast masses. As it is sensitive, specific, economical and safe for screening of breast lesions Aims and objectives – to determine the histopathologic correlation of FNAC of breast lumps seen in department of pathology, Govt medical college, siddipet. Methods – 2 yrs. retrospective study if breast lumps , with all patients who had FNAC, with subsequent histopathological confirmation over the period July 2018 –July 2020. A total 232 cases included in which 187 cases are subjected to excision biopsy or mastectomy Results –2 yrs. under review (2018-2020) a total of 232 FNAC of breast lump were done. 197 (84.9%) benign cases, 13(11.6%) malignant cases, 8 (3.5%) inflammatory cases were diagnosed cytologically in which 98(42.24%) cases are fibro adenoma, 27(11.6%) are malignant cases and suspicious of malignancy, 26(11.2%) of gynecomastia, 23(9.91%) of fibrocystic disease with female predominance of 8:1 ratio (206:26). Age ranging from 9 yrs. – 85 yrs. with mean age of 47yrs ± 14.2 yrs. Conclusion – we therefore concluded that FNAC is a reliable diagnostic tool of breast lump in our hospital. FNAC guides the surgeons for further plan of management.


2016 ◽  
Author(s):  
S. Dash ◽  
A. Goel ◽  
S. Sogani

Purpose: To evaluate the role of 18F-FDG PET with contrast enhanced CT (PET-CECT) in early detection of recurrence in follow up patients of carcinoma cervix. Methods: Patients with histopathologically proven carcinoma cervix who underwent chemotherapy, radiotherapy and/or surgery and on follow up were recruited in the study. Fifty-two patients underwent 18F-FDG PET-CECT for detection of recurrence. The median age was 51.5 (average = 53.4) years. PET-CECT studies were evaluated and analyzed separately by an experienced nuclear medicine physician and a radiologist independently. The physicians were blinded for the patient history. PET-CECT results were validated with histopathological correlation, conventional radiologic imaging/follow up PET-CECT study and clinical follow up. Results: Out of 52 patients, 34 patients were reported as positive for recurrence, 17 of these were having active local recurrence and 31 patients had regional lymph nodal metastases, 14 patients had distant metastases (out of them 6 patients had distant lymph node metastases, 6 had pulmonary metastases, 4 had skeletal metastases and two had liver metastases). Remaining 18 patients were reported as negative for recurrence. The lung was the most common site for distant metastasis. Patient were then further evaluated based on histopathological correlation, conventional radiologic imaging and follow up PET-CECT scan and five were found to be false positive and one patient was identified as false negative. The sensitivity, specificity, positive and negative predictive value were derived to be 96.7%, 77.3%, 85.3% and 94.4%, respectively. Accuracy was calculated to be 88.5%. Conclusions: 18F-FDG PET-CECT is a very useful non-invasive modality for the early detection of recurrence and metastatic workup in patients with carcinoma cervix with a very high sensitivity and negative predictive value. It is also useful in targeting biopsy sites in suspected cases of recurrence.


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