scholarly journals A clinical case of Kaposi sarcoma in a patient with TB/HIV co-infection

2020 ◽  
Vol 98 (7) ◽  
pp. 63-68
Author(s):  
N. V. Kuzmina ◽  
N. V. Nelidova
Keyword(s):  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Clinical Case ◽  
Kaposi Sarcoma ◽  
Antiretroviral Drugs ◽  
T Cell Immunity ◽  
Adherence To Treatment ◽  
Cell Immunity ◽  
Viral Hepatitis B

The article describes a clinical case of Kaposi sarcoma in a patient with concurrent tuberculosis, HIV infection with severely compromised T-cell immunity, viral hepatitis B and C, and substances and alcohol abuse. Also, the patient had low adherence to treatment with anti-tuberculosis and antiretroviral drugs.

scholarly journals PREVALENCE AND MOLECULAR GENETIC PECULIARITIES OF PARENTERAL VIRAL HEPATITIS B AND C AMONG HIVPOSITIVE CITIZENS OF THE FAR EASTERN FEDERAL DISTRICT, INCLUDING THOSE PERSONS SENTENCED TO DEPRIVATION OF FREEDOM

2019 ◽  
pp. 51-55
Author(s):  
E.A. Bazykina ◽  
V.B. Turkutyukov ◽  
O.E. Trotsenko ◽  
V.O. Kotova ◽  
L.A. Balakhonsteva ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Molecular Genetic ◽  
Federal District ◽  
Biological Research ◽  
Hiv Positive ◽  
Healthy Population ◽  
Genetic Characteristics ◽  
Viral Hepatitis B

We conducted a comparative analysis of the parenteral viral hepatitis B and C (HBV and HCV) prevalence and their molecular genetic characteristics among prisoners of persons diagnosed with HIV infection (41 samples), HIV-positive free citizens (187 samples) and «conditionally healthy population» with the lack of information about the presence of a diagnosis of chronic viral hepatitis of any etiology and HIV infection (231 samples). Immunological and molecular biological research methods were used. Obtained data analysis showed that the prevalence of infection markers with viruses of parenteral hepatitis was significantly higher in the groups of HIV-positive individuals (imprisoned and freemen). The HBsAg-negative form of the disease was determined among the HIV-positive free population and in the «conditionally healthy population». Over the past 10 years (2009–2018), the proportion of HIV-positive prisoners in custody of people with HCV monoinfection doubled, HBV was increased in 8.7 times. Significant decrease in the combined infection of HBV and HCV of this contingent was found. Given this decrease in the penitentiary system in HIV-positive individuals, the overall burden of HBV infection (both in mono form and coinfection with HCV) significantly (5.3 times) decreased , which can be attributed to successful widespread vaccination against hepatitis B in Russia. The most common HCV genotypes among HIV-positive individuals were 1b and 3a, genotypic structure of HBV prevailed genotype D.

scholarly journals Acute viral hepatitis B in infants: a clinical case

2021 ◽  
Vol 20 (1) ◽  
pp. 65-68
Author(s):  
A. V. Vasyunin ◽  
G. S. Karpovich ◽  
E. I. Krasnova ◽  
I. V. Kuimova ◽  
N. I. Gavrilova ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Viral Hepatitis ◽  
Clinical Case ◽  
Clinical Observation ◽  
Acute Viral Hepatitis ◽  
Morbidity And Mortality ◽  
Routine Vaccination ◽  
Viral Hepatitis B

Routine vaccination against viral hepatitis B (HBV) has significantly reduced morbidity and mortality from this infection. The development of acute HBV in children is currently a rarity, but there is still the possibility of developing a similar scenario in children from family foci of HBV, aswell as in children with no specific prophylaxis. A clinical observation of the development of acute HBV in aninfant is presented, and the difficulties of managing such patients are demonstrated.

scholarly journals Epidemiological Surveillance over HIV-infection Including Patients Co-infected with HIV and Viral Hepatitis in the Far Eastern Federal District

2019 ◽  
Vol 18 (4) ◽  
pp. 14-24
Author(s):  
E. A. Bazykina ◽  
V. B. Turkutyukov ◽  
O. E. Trotsenko ◽  
I. O. Taenkova ◽  
L. A. Balakhontseva ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Federal District ◽  
Epidemiological Surveillance ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Infected People ◽  
Viral Hepatitis B ◽  
Far Eastern

Relevance. HIV-infection continues to be one of the unsolved issues of modern healthcare. In the Russian Federation, an annual increase in the number HIV-infected people including co-infected with HIV and viral hepatitis is registered. This is associated with common transmission mechanisms of the diseases. Objective: to conduct a retrospective analysis of the main HIV-infection epidemiological indices that included prevalence of viral hepatitis B and C among people living with HIV in the Far Eastern Federal district during years 2006–2018. Materials and methods: the conducted retrospective epidemiological analysis was based on evaluation of materials provided by AIDS prevention and control regional centers as well as in the official statistical data form № 61 «Data on HIVinfected contingents». Analysis of the obtained data included parametric and nonparametric statistics. Results. A deterioration of the epidemic situation concerning HIV-infection with and without viral hepatitis B and C was registered in the Far Eastern Federal district. The fraction of HIV-positive people aged 40 years and older increased up to 24.68 ± 0.26% in 2018. Feminization of HIV-infected population was observed. The fraction of HIV-positive women increased from 32.30 ± 0.50 % in 2006 to 36.82 ± 0.29% in 2018. The fraction of sexual transmission mechanism of the HIV has increased during the observed period of time and totaled 40.60 ± 0.30% in 2018. This fact plays a significant part in the spread of HIV in the Far Eastern Federal district. Conclusion. The revealed tendencies indicate a necessity of changing the preventive measures strategy against HIV.

scholarly journals LETHALITY OF TB PATIENTS, COMBINED WITH THE VIRAL HEPATITIS AND HIV INFECTION IN SAINT-PETERSBURG

2019 ◽  
Vol 11 (2) ◽  
pp. 42-47
Author(s):  
A. K. Ivanov ◽  
V. V. Nechaev ◽  
L. N. Pozhidayeva ◽  
V. B. Musatov ◽  
V. S. Belyakov ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Fatal Outcome ◽  
Chronic Viral Hepatitis ◽  
Unknown Etiology ◽  
Saint Petersburg ◽  
Viral Hepatitis B ◽  
High Level

Сombination of tuberculosis and viral hepatitis have been registered 2525 newly identified patients in Saint-Petersburg for the period 2006–2017. Some of these patients have been infected with HIV. Fatal outcome in 625 (24,7%) was noted. Patients with tuberculosis and chronic viral hepatitis have had a combination of viral hepatitis B and C in 36% of cases. Patients with combination tuberculosis and chronic hepatitis of unknown etiology experienced a more frequent death (60%) than patients with combination tuberculosis and other chronic viral hepatitis. In patients with concurrent tuberculosis, chronic viral hepatitis and HIV infection, patients infected viral hepatitis B and C were 31,6%. In 160 patients with fatal outcomes had a combination of infections (tuberculosis, viral hepatitis and HIV infection), the mortality rate of persons with hepatitis of unknown etiology was the lowest (42%), compared with a group of individuals affected by viral hepatitis B and C simultaneously (83%). Among patients with tuberculosis, chronic hepatitis and HIV infection, the highest incidence of tuberculosis of the intrathoracic lymph nodes and disseminated pulmonary tuberculosis was registered. Lethal outcomes most often occur in individuals with advanced tuberculosis, in whom the secretion of mycobacteria tuberculosis into the external environment has not been established. Given the high level of mortality in patients with simultaneous defeat of tuberculosis, viral hepatitis and HIV infection, it is necessary to establish their centralized registration in order to study the epidemiological patterns and clinical features of co-infections.

Survival in patients with HIV infection and viral hepatitis B or C

AIDS ◽  
2004 ◽  
Vol 18 (15) ◽  
pp. 2039-2045 ◽  
Author(s):  
Maurizio Bonacini ◽  
Stan Louie ◽  
Natalie Bzowej ◽  
Amy Rock Wohl
Keyword(s):  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Viral Hepatitis B

Diabetes Among People With Tuberculosis, HIV Infection, Viral Hepatitis B and C, and STDs in New York City, 2006-2010

2017 ◽  
Vol 23 (5) ◽  
pp. 461-467 ◽  
Author(s):  
Ann Drobnik ◽  
Alexander Breskin ◽  
Jennifer Fuld ◽  
Christine Chan ◽  
James Hadler ◽  
...  
Keyword(s):  
New York ◽  
New York City ◽  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
York City ◽  
Viral Hepatitis B

METASTATIC CHOLANGIOCARCINOMA AS A TARGET OF MOLECULAR-DIRECTED THERAPY

2018 ◽  
Vol 64 (5) ◽  
pp. 671-677
Author(s):  
Valeriy Breder ◽  
Irina Dzhanyan ◽  
Andrey Zaretskiy ◽  
Konstantin Laktionov ◽  
M. Natrusova
Keyword(s):  
Targeted Therapy ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Clinical Case ◽  
Term Effect ◽  
Short Term ◽  
Short Term Effect ◽  
Oncogenic Mutations ◽  
Viral Hepatitis B ◽  
Alk Positive

It is reported a unique clinical case of administration of crizotinib in a 14-year-old patient with ALK-positive metastatic cholangiocarcinoma and congenital viral hepatitis B. Driver oncogenic mutations potentially responsive to targeted therapy as well as possible ways to prolong crizotinib short-term effect are discussed.

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