This chapter argues that the radicalization of monetary policy, regulatory transformation, and central bank innovation in the US and the UK emerged out of institutional complementarities and interdependencies generated by Anglo-American development. The development of offshore markets in the City of London led bankers on both sides of the Atlantic to push for further domestic liberalization, as competition between London and New York intensified. US banks pressured regulators to replicate the City's offshore conditions, which gradually eroded New Deal-era financial regulations. These dynamics, alongside the Fed's failure to regulate the Euromarkets, demonstrated both the limits on US monetary policy autonomy and the importance of the transatlantic impetus to liberalization emerging from Anglo-American financial integration. Embracing monetarism, Margaret Thatcher and Ronald Reagan made clear that price stability would be restored and that working-class solidarity would be broken. In the absence of the Bretton Woods framework, both states demonstrated their commitment to internalizing discipline through extreme applications of monetary policy and direct confrontations with the labor movement. Ultimately, developments in the UK and the US led the way for the broader adoption of neoliberalism within the global political economy and the further development of financialization.