Recipient Gender and Body Mass Index are Associated with Early Acute Rejection in Donation after Cardiac Death Liver Transplantation

2018 ◽  
Author(s):  
Qiang Wei ◽  
Kun Wang ◽  
Modan Yang ◽  
Junli Chen ◽  
Tian Shen ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Liver Transplantation ◽  
Acute Rejection ◽  
Body Mass ◽  
Cardiac Death ◽  
Donation After Cardiac Death

scholarly journals Recipient gender and body mass index are associated with early acute rejection in donation after cardiac death liver transplantation

2020 ◽  
Vol 1 ◽  
pp. 100004
Author(s):  
Qiang Wei ◽  
Kun Wang ◽  
Modan Yang ◽  
Junli Chen ◽  
Tian Shen ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Liver Transplantation ◽  
Acute Rejection ◽  
Body Mass ◽  
Cardiac Death ◽  
Donation After Cardiac Death

Effect of Donor Body Mass Index on the Outcome of Donation After Cardiac Death Kidneys: How Big is Too Big?

2014 ◽  
Vol 46 (1) ◽  
pp. 46-49 ◽  
Author(s):  
L.X. Jin ◽  
S.C. Pitt ◽  
M.B. Doyle ◽  
C. Klein ◽  
S. Shenoy ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Cardiac Death ◽  
Donation After Cardiac Death

ECG markers of sudden cardiac death among body mass index groups

2020 ◽  
Vol 23 (06) ◽  
pp. 08-12
Author(s):  
Yasir Salah Alam ◽  
Karar Nadhm Obaid Aljabry ◽  
Hussein Nafakhi ◽  
Abdulameer A. AlMosawi ◽  
Hasan A. Al-Nafakh
Keyword(s):  
Body Mass Index ◽  
Sudden Cardiac Death ◽  
Body Mass ◽  
Cardiac Death

scholarly journals Association between body mass index and 1-year outcome after acute myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D.W Kim
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Body Mass Index ◽  
Confidence Interval ◽  
Body Mass ◽  
Cardiac Death ◽  
Funding Source ◽  
Group Iii ◽  
End Point ◽  
Group I

Abstract Background Beneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as “Body Mass Index (BMI) paradox”. However, the effects of BMI is still on debate. We analyzed the association between BMI and 1-year major cardiocerebrovascular events (MACCE) after AMI. Methods and findings Among 13,104 AMI patients registered in an Institute of Health in Korea between November 2011 and December 2015, 10,568 patients who eligible for this study were classified into 3 groups according to BMI (Group I; <22 kg/m2, 22 ≤ Group II <26 kg/m2, Group III; ≥26 kg/m2). The primary end point was a composite of cardiac death (CD), myocardial infarction (MI), target vessel revascularization (TVR), and cerebrovascular events at 1 year. Over the median follow-up of 12 months, the composite of primary end point occurred more frequently in the Group I patients than in the Group III patients (primary endpoint: adjusted hazard ratio [aHR], 1.290; 95% confidence interval [CI] 1.024 to 1.625, p=0.031). Especially, cardiac death in MACCE components played a major role in this effect (aHR, 1.548; 95% confidence interval [CI] 1.128 to 2.124, p=0.007). Conclusions Higher BMI appeared to be good prognostic factor on 1-year MACCE after AMI. This result suggests that higher BMI or obesity might confer a protective advantage over the life-quality after AMI. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): Research of Korea Centers for Disease Control and Prevention and the Korea Health Technology R&D Project, Ministry of Health & Welfare (HI13C1527), Republic of Korea.

Hospital Resource Use with Donation after Cardiac Death Allografts in Liver Transplantation: A Matched Controlled Analysis from 2007 to 2011

2015 ◽  
Vol 220 (5) ◽  
pp. 951-958 ◽  
Author(s):  
Ashish Singhal ◽  
Koffi Wima ◽  
Richard S. Hoehn ◽  
R. Cutler Quillin ◽  
E. Steve Woodle ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Resource Use ◽  
Cardiac Death ◽  
Donation After Cardiac Death ◽  
Hospital Resource

Increased Recipient Body Mass Index Is Associated With Acute Rejection and Other Adverse Outcomes After Kidney Transplantation

2014 ◽  
Vol 97 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Simon P. Curran ◽  
Olusegun Famure ◽  
Yanhong Li ◽  
S. Joseph Kim
Keyword(s):  
Body Mass Index ◽  
Kidney Transplantation ◽  
Acute Rejection ◽  
Body Mass ◽  
Adverse Outcomes

scholarly journals Warm ischemia time and elevated serum uric acid are associated with metabolic syndrome after liver transplantation with donation after cardiac death

2018 ◽  
Vol 24 (43) ◽  
pp. 4920-4927
Author(s):  
Liang-Shuo Hu ◽  
Yi-Chao Chai ◽  
Jie Zheng ◽  
Jian-Hua Shi ◽  
Chun Zhang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Liver Transplantation ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Cardiac Death ◽  
Elevated Serum ◽  
Warm Ischemia ◽  
Warm Ischemia Time ◽  
Donation After Cardiac Death ◽  
Ischemia Time

Liver graft preservation using perfluorocarbon improves the outcomes of simulated donation after cardiac death liver transplantation in rats

2017 ◽  
Vol 23 (9) ◽  
pp. 1171-1185 ◽  
Author(s):  
Shinya Okumura ◽  
Tadahiro Uemura ◽  
Xiangdong Zhao ◽  
Yuki Masano ◽  
Tatsuaki Tsuruyama ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Cardiac Death ◽  
Liver Graft ◽  
Donation After Cardiac Death ◽  
Graft Preservation

Body mass index, weight-adjusted immunosuppression and the risk of acute rejection and infection after kidney transplantation: a cohort study

2019 ◽  
Vol 34 (12) ◽  
pp. 2132-2143 ◽  
Author(s):  
Katerina Flabouris ◽  
Steven Chadban ◽  
Maleeka Ladhani ◽  
Matthew Cervelli ◽  
Philip Clayton
Keyword(s):  
Body Mass Index ◽  
Kidney Transplantation ◽  
Acute Rejection ◽  
Body Mass ◽  
Cox Models ◽  
Fatal Infection ◽  
Adult Kidney ◽  
Transplant Registry ◽  
Index Weight ◽  
Time Varying Covariates

Abstract Background Body mass index (BMI) is associated with patient outcomes after kidney transplantation. We hypothesized that immunosuppression (IS) dosing is a contributing factor. Methods Using Australia and New Zealand Dialysis and Transplant registry data, we included all adult kidney-only transplant recipients over 2000–14 treated with prednisolone, mycophenolate and tacrolimus/cyclosporin (n = 7919). The exposure was BMI and the outcomes were time to: (i) acute rejection, (ii) fatal infection, (iii) cancer and (iv) graft; and (v) patient survival. We modelled BMI and IS dosing (in quartiles) as time-varying covariates in extended Cox models. Results Compared with a BMI of 25 kg/m2, a BMI of 35 was associated with acute rejection after adjusting for demographics and comorbidities [adjusted hazard ratio (aHR) = 1.29, 95% confidence interval (CI) 1.12–1.49]. This association virtually disappeared after correcting for IS (aHR = 1.09, 95% CI 0.93–1.29). A BMI of 35 was non-significantly associated with fewer fatal infections (aHR = 0.91, 95% CI 0.66–1.25), but this reversed after adjusting for IS (aHR = 1.54, 95% CI 1.03–2.28). Results for cancer were not significantly altered after adjusting for IS. Results for lower BMI were similarly not significantly altered though generally associated with worse outcomes. Conclusions Our findings show that the associations between high BMI, acute rejection and fatal infection after kidney transplantation were significantly altered after correcting for IS suggesting that relative under-dosing of obese patients may partially explain these associations.

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