Ethnic disparity in altruism towards reforestation: A social preference experiment in Mindoro, Philippines

The paper studies the sensitivity implications of the class of monotone social preference orders on infinite utility streams which satisfy the axioms of Equity (Finite Anonymity) and Stationarity (Independent Future). The principal result of this investigation is that representability of such preference orders implies a certain lack of sensitivity to the utility stream of any finite number of generations, which we refer to as ‘insensitivity to the present’. Our result points to a fundamental difficulty in implementing the sustainability principle, which requires intertemporal social preferences to reflect fairly the interests of the generations in the present and in the future.

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Childhood social preference and adolescent insulin resistance: Accounting for the indirect effects of obesity

Psychoneuroendocrinology ◽

10.1016/j.psyneuen.2019.104557 ◽

2020 ◽

Vol 113 ◽

pp. 104557

Author(s):

Meghan J. Gangel ◽

Jessica Dollar ◽

Ashley Brown ◽

Susan Keane ◽

Susan D. Calkins ◽

...

Keyword(s):

Insulin Resistance ◽

Indirect Effects ◽

Social Preference

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Structural and functional brain-wide alterations in A350V Iqsec2 mutant mice displaying autistic-like behavior

Translational Psychiatry ◽

10.1038/s41398-021-01289-8 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Daniela Lichtman ◽

Eyal Bergmann ◽

Alexandra Kavushansky ◽

Nadav Cohen ◽

Nina S. Levy ◽

...

Keyword(s):

Social Behavior ◽

Functional Connectivity ◽

Mouse Model ◽

Ampa Receptor ◽

Social Preference ◽

Autism Spectrum ◽

Receptor Trafficking ◽

Anterior Cingulate ◽

The Impact ◽

Ampa Receptor Trafficking

AbstractIQSEC2 is an X-linked gene that is associated with autism spectrum disorder (ASD), intellectual disability, and epilepsy. IQSEC2 is a postsynaptic density protein, localized on excitatory synapses as part of the NMDA receptor complex and is suggested to play a role in AMPA receptor trafficking and mediation of long-term depression. Here, we present brain-wide structural volumetric and functional connectivity characterization in a novel mouse model with a missense mutation in the IQ domain of IQSEC2 (A350V). Using high-resolution structural and functional MRI, we show that animals with the A350V mutation display increased whole-brain volume which was further found to be specific to the cerebral cortex and hippocampus. Moreover, using a data-driven approach we identify putative alterations in structure–function relations of the frontal, auditory, and visual networks in A350V mice. Examination of these alterations revealed an increase in functional connectivity between the anterior cingulate cortex and the dorsomedial striatum. We also show that corticostriatal functional connectivity is correlated with individual variability in social behavior only in A350V mice, as assessed using the three-chamber social preference test. Our results at the systems-level bridge the impact of previously reported changes in AMPA receptor trafficking to network-level disruption and impaired social behavior. Further, the A350V mouse model recapitulates similarly reported brain-wide changes in other ASD mouse models, with substantially different cellular-level pathologies that nonetheless result in similar brain-wide alterations, suggesting that novel therapeutic approaches in ASD that result in systems-level rescue will be relevant to IQSEC2 mutations.

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Female gastrin-releasing peptide receptor (GRP-R)-deficient mice exhibit altered social preference for male conspecifics: implications for GRP/GRP-R modulation of GABAergic function

Brain Research ◽

10.1016/s0006-8993(01)02032-7 ◽

2001 ◽

Vol 894 (2) ◽

pp. 281-287 ◽

Cited By ~ 16

Author(s):

Kazuyuki Yamada ◽

Etsuko Wada ◽

Keiji Wada

Keyword(s):

Social Preference ◽

Peptide Receptor ◽

Gastrin Releasing Peptide ◽

Gabaergic Function ◽

Deficient Mice

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Acute environmental temperature variation affects brain protein expression, anxiety and explorative behaviour in adult zebrafish

Scientific Reports ◽

10.1038/s41598-021-81804-5 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

S. Nonnis ◽

E. Angiulli ◽

E. Maffioli ◽

F. Frabetti ◽

A. Negri ◽

...

Keyword(s):

Nervous System ◽

Cognitive Abilities ◽

Messenger Rna ◽

Chronic Treatment ◽

Social Preference ◽

Adult Zebrafish ◽

Proteomic Data ◽

Messenger Rna Translation ◽

Behavioural Tests ◽

Past Experiences

AbstractThis study investigated the effect of 4-d acute thermal treatments at 18 °C, 26 °C (control) and 34 °C on the nervous system of adult zebrafish (Danio rerio) using a multidisciplinary approach based on behavioural tests and brain proteomic analysis. The behavioural variations induced by thermal treatment were investigated using five different tests, the novel tank diving, light and dark preference, social preference, mirror biting, and Y-Maze tests, which are standard paradigms specifically tailored for zebrafish to assess their anxiety-like behaviour, boldness, social preference, aggressiveness, and explorative behaviour, respectively. Proteomic data revealed that several proteins involved in energy metabolism, messenger RNA translation, protein synthesis, folding and degradation, cytoskeleton organisation and synaptic vesiculation are regulated differently at extreme temperatures. The results showed that anxiety-like behaviours increase in zebrafish at 18 °C compared to those at 26 °C or 34 °C, whereas anxiety-related protein signalling pathways are downregulated. Moreover, treatments at both 18 °C and 34 °C affect the exploratory behaviour that appears not to be modulated by past experiences, suggesting the impairment of fish cognitive abilities. This study is the continuation of our previous work on the effect of 21-d chronic treatment at the same constant temperature level and will enable the comparison of acute and chronic treatment effects on the nervous system function in adult zebrafish.

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