scholarly journals Development and Validation of a Nomogram Model to Predict Acute Kidney Disease After Nephrectomy in Patients with Renal Cell Carcinoma [Erratum]

2021 ◽  
Vol Volume 13 ◽  
pp. 8511-8512
Author(s):  
Xiao-Ying Hu ◽  
Dong-Wei Liu ◽  
Ying-Jin Qiao ◽  
Xuan Zheng ◽  
Jia-Yu Duan ◽  
...  

2020 ◽  
Vol Volume 12 ◽  
pp. 11783-11791
Author(s):  
Xiao-Ying Hu ◽  
Dong-Wei Liu ◽  
Ying-Jin Qiao ◽  
Xuan Zheng ◽  
Jia-Yu Duan ◽  
...  


2021 ◽  
Vol 22 (8) ◽  
pp. 3918
Author(s):  
Cassandra Millet-Boureima ◽  
Stephanie He ◽  
Thi Bich Uyen Le ◽  
Chiara Gamberi

Renal cell carcinoma (RCC) and autosomal dominant polycystic kidney disease (ADPKD) share several characteristics, including neoplastic cell growth, kidney cysts, and limited therapeutics. As well, both exhibit impaired vasculature and compensatory VEGF activation of angiogenesis. The PI3K/AKT/mTOR and Ras/Raf/ERK pathways play important roles in regulating cystic and tumor cell proliferation and growth. Both RCC and ADPKD result in hypoxia, where HIF-α signaling is activated in response to oxygen deprivation. Primary cilia and altered cell metabolism may play a role in disease progression. Non-coding RNAs may regulate RCC carcinogenesis and ADPKD through their varied effects. Drosophila exhibits remarkable conservation of the pathways involved in RCC and ADPKD. Here, we review the progress towards understanding disease mechanisms, partially overlapping cellular and molecular dysfunctions in RCC and ADPKD and reflect on the potential for the agile Drosophila genetic model to accelerate discovery science, address unresolved mechanistic aspects of these diseases, and perform rapid pharmacological screens.



Cell Cycle ◽  
2006 ◽  
Vol 5 (24) ◽  
pp. 2839-2841 ◽  
Author(s):  
Benedetta Peruzzi ◽  
Donald P. Bottaro








Urology ◽  
2020 ◽  
Vol 144 ◽  
pp. 152-157
Author(s):  
Michael Fenstermaker ◽  
Scott A. Tomlins ◽  
Karandeep Singh ◽  
Jenna Wiens ◽  
Todd M. Morgan


2019 ◽  
Vol 16 (5) ◽  
pp. S18
Author(s):  
P. Capogrosso ◽  
U. Capitanio ◽  
A. Larcher ◽  
F. Muttin ◽  
E. Ventimiglia ◽  
...  






Sign in / Sign up

Export Citation Format

Share Document