scholarly journals Socio-Demographic, Economic and Clinical Predictors for HAART Adherence Competence in HIV-Positive Adults at Felege Hiwot Teaching and Specialized Hospital, North West Ethiopia

2021 ◽  
Vol Volume 13 ◽  
pp. 749-758
Author(s):  
Awoke Seyoum Tegegne
BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e033393
Author(s):  
Adhanom Gebreegziabher Baraki ◽  
Lemma Derseh Gezie ◽  
Ejigu Gebeye Zeleke ◽  
Tadesse Awoke ◽  
Adino Tesfahun Tsegaye

ObjectivesThis study aimed to assess the evolution of body mass index (BMI) of HIV-positive adults on second-line antiretroviral therapy (ART) over time and factors affecting it in north-west Ethiopia.DesignAn institution-based retrospective follow-up study was conducted using data extracted from 1016 patient cards from February 2008 to February 2016.SettingEight referral hospitals from Amhara region, Ethiopia were included.ParticipantsHIV patients who started second-line ART.Outcome measuresChange in BMI since starting second-line ART.ResultsFive hundred and thirty-eight (52.95%) participants were males and the median age of the participants was 33 years (IQR: 28; 39). The median follow-up time was 18 months (IQR: 5.2; 32.2). The average change of BMI showed linear increase over time. The amount of BMI increment or decrement according to each variable was shown as β coefficients. Treatment duration (β=0.013, 95% CI 0.004 to 0.022), isoniazid prophylaxis (β=0.87, 95% CI 0.32 to 1.42), cotrimoxazole prophylaxis (β=0.63, 95% CI 0.08 to 1.19), ambulatory functional status (β=−1.16, 95% CI −1.95 to 1.31), bedridden functional status (β=−1.83, 95% CI −2.47 to 1.21), WHO stage III (β=−0.42, 95% CI −0.65 to 0.20), WHO stage IV (β=−0.62, 95% CI −1.02 to 0.22), CD4 count (β=0.001, 95% CI 0.0008 to 0.0015), and time interaction of variables like tertiary educational status (β=0.02, 95% CI 0.01 to 0.04), ambulatory functional status (β=0.03, 95% CI 0.01 to 0.05) and WHO stages III (β=0.01, 95% CI 0.007 to 0.02) were found to be significant predictors.ConclusionThe BMI of patients has shown linear increment over the treatment time. Factors affecting it have been identified but its effect on cardiovascular disease needs further study.


PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0251708
Author(s):  
Bekele Taye Feleke ◽  
Mengistu Zelalem Wale ◽  
Mesenbet Terefe Yirsaw

Background COVID-19 is an emerging infectious disease which is a major public health problem worldwide. Given the serious threats imposed by COVID-19 and the absence of vaccines until August 2020, preventive measures play an essential role in reducing infection rates and controlling its spread. This shows the necessity of public adherence for preventive and control measures, which is affected by their knowledge, attitudes, and practices. Objective This study aimed to determine knowledge, attitude, and practice (KAP) towards COVID-19 and associated factors among outpatient service visitors, Debre Markos compressive specialized hospital, north-west,Ethiopia. Method Institutional-based cross-sectional study design with a systematic random sampling technique was conducted from July to August 2020. Among a total of 404 participants, 398 were recruited. Data were collected using a structured questionnaire. The data was edited, coded, and entered into Epi data version 4.6 and exported to SPSS-25 for analysis. Bivariable and multivariable logistic regression models were employed to identify factors associated with KAP. A p-value of <0.05 was considered statistically significant. Result The prevalence of poor knowledge, attitude and practice among the outpatient service visitors were 27.1%, 30.7% and 44%, respectively. The mean age of the participants was 33.4 ±10.9 years. Variables like; educational status, ‘‘can’t read and write” [AOR = 3.76, 95% CI (1.36–10.42), P = 0.01], read and write [AOR = 5.90, 95% CI (2.39–14.98), P = 0.01], rural residence [AOR = 3.04, 95% CI (1.43–6.46), P = 0.01] and having no television [AOR = 0.8, 95% CI (0.79–0.89), P = 0.03] were significantly associated with poor knowledge. While, educational status of “can’t read and write”, [AOR = 6.71, 95% CI (2.78–16.16), P = 0.01] and rural residence [AOR = 2.03, 95% CI (1.14–3.61), P = 0.02] were significantly associated with poor attitude. Additionally, poor knowledge, [AOR = 22.73, 95% CI (10.5–49.21), P = 0.01], rural residence [AOR = 2.08, 95% CI (1.08–4.88), P = 0.04] and having no television [AOR = 2.24, 95% CI (1.05–4.79), P = 0.01] were significantly associated with poor practice. Conclusion In this study, knowledge, attitude, and practice among outpatient service visitors was poor which needs targeted health education and interventions from the health professional to enhance their knowledge, attitude, and practice towards COVID-19. In parallel with this, special attention should be given for the rural community and for those with an educational status of can’t read and write.


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