scholarly journals Levels of Adherence and Associated Factors Among Children on ART Over Time in Northwest, Ethiopia: Evidence from a Multicenter Follow-Up Study [Corrigendum]

2021 ◽  
Vol Volume 13 ◽  
pp. 903-904
Author(s):  
Fisha GebreEyesus ◽  
Dagninet Mitku ◽  
Tadesse Tarekegn ◽  
Bogale Temere ◽  
Tamene Terefe ◽  
...  
2021 ◽  
Vol Volume 13 ◽  
pp. 829-838
Author(s):  
Fisha GebreEyesus ◽  
Dagninet Mitku ◽  
Tadesse Tarekegn ◽  
Bogale Temere ◽  
Tamene Terefe ◽  
...  

Author(s):  
Soundarya Soundararajan ◽  
Arpana Agrawal ◽  
Meera Purushottam ◽  
Shravanthi Daphne Anand ◽  
Bhagyalakshmi Shankarappa ◽  
...  

2021 ◽  
pp. 089033442110301
Author(s):  
Hannah G. Juncker ◽  
M. Romijn ◽  
Veerle N. Loth ◽  
Tom G. Caniels ◽  
Christianne J.M. de Groot ◽  
...  

Background: Human milk contains antibodies against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) following Coronavirus Disease 2019 (COVID-19). These antibodies may serve as protection against COVID-19 in infants. However, the evolution of these human milk antibodies over time is unclear. Research Aim: To elucidate the evolution of immunoglobulin A (IgA) against SARS-CoV-2 in human milk after a SARS-CoV-2 infection. Methods: This longitudinal follow-up study included lactating mothers ( N = 24) who had participated in the COVID MILK study. To assess the evolution of SARS-CoV-2 antibodies, serum and human milk samples were collected 14–143 days after the onset of clinical symptoms related to COVID-19. Enzyme-Linked ImmunoSorbent Assay was used to detect antibodies against the ectodomain of the SARS-CoV-2 spike protein. Results: SARS-CoV-2 antibodies remain present up to 5 months (143 days) in human milk after onset of COVID-19 symptoms. Overall, SARS-CoV-2 IgA in human milk seems to gradually decrease over time. Conclusion: Human milk from SARS-CoV-2 convalescent lactating mothers contains specific IgA antibodies against SARS-CoV-2 spike protein up to at least 5 months post-infection. Passive viral immunity can be transferred via human milk and may serve as protection for infants against COVID-19. Dutch Trial Register on May 1st, 2020, number: NL 8575, URL: https://www.trialregister.nl/trial/8575 .


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
April L. Shapiro ◽  
Joeli Olson ◽  
Saima Shafique ◽  
Ubolrat Piamjariyakul

2020 ◽  
Author(s):  
Yidrsail Hune ◽  
Hirut Asaye ◽  
Ayenew Negesse ◽  
Habtamu Temesgen ◽  
Tadesse Yirga ◽  
...  

Abstract Background: Vitamin A is a fat-soluble vitamin essential for the proper functioning of the immune system. It fondes both animal and plant sources in the form of retinol from animal sources or beta-carotene from plant source foods. Due to increased nutrient need and the severity of the potential health consequences are associated with vitamin A deficiency (VAD), preschool children and pregnant women are considered as the most at risk segments of the community. Hence, this study aimed to assess the prevalence of VAD and associated factors among children aged 6-59 months in Dera woreda, Northwest Ethiopia. Methods: Community based quantitative cross-sectional study was conducted among children aged 6-59 months in Dera woreda from December 1/2018 to January 1/2019. Multistage random sampling was used to select the required samples (267). Data were coded and entered into Epi-data version 3.1 and exported to SPSS (Statistical Package for Social Sciences) version 20 for analysis. Binary logistic regression was fitted. Both bivariable and multivariable analyses were used to identify factors associated with VAD. Those variables that were showed significant association in multivariable association at P value less than 0.05 declared as statistically significant factors of VAD among children age 6-59 months. Results: Two hundred sixty seven mother-children Pairs were included in the study making a response rate of 94.7%. The overall prevalence of Vitamin A deficiency among children age 6-59 months was 7.8% (95% CI (4.7, 11.3). Antenatal care follow up (AOR: 0.446,95 % CI (0.155, 0.980)); birth interval within 2 year (AOR: 0.392, 95 % CI (0.107, 0.839)), and age group of24-35 months (AOR; 1.206, 95 % CI (1.037, 6.129)) were significantly associated with vitamin-A deficiency. Conclusion: The overall prevalence of vitamin A deficiency in this study was found to be lower than the national and regional prevalence. According to this study, VAD is a mild public health problem. Age of children, birth interval, ANC follow up, remain the most important associated factors for vitamin A deficiency. Therefore to decrease the prevalence of VAD, ANC service should be strengthened and we should focus on older children birth interval and age- based food needs.


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