scholarly journals High plasma concentration of beta-D-glucan after administration of sizofiran for cervical cancer

Author(s):  
Tokuyasu Hirokazu
1969 ◽  
Vol 21 (02) ◽  
pp. 320-324 ◽  
Author(s):  
K Seiler ◽  
F Duckert

SummaryA case of severe Marcoumar intoxication is described. Eleven hours after the intake a plasma concentration of 15.75 µg/ml was found which corresponds approximately to the 5-fold therapeutic concentration. Repeated administration of vitamin K1 made it possible to avoid extreme lowering of the activity of the clotting factors II, VII and X and to prevent bleeding. Side effects were not observed. The biologic half-life of Phenprocoumon has been found to be shortened at high plasma concentration (3.7 instead of 5.9 days). It is probable that in extreme concentration the drug is less strongly bound to the plasma proteins.


2020 ◽  
Vol 80 ◽  
pp. 52-55 ◽  
Author(s):  
Stéphane Jaisson ◽  
Aurore Desmons ◽  
Antoine Braconnier ◽  
Alain Wynckel ◽  
Philippe Rieu ◽  
...  

2020 ◽  
Author(s):  
Maxime Nguyen ◽  
Abderrahmane Bourredjem ◽  
Lionel Piroth ◽  
Bélaïd Bouhemad ◽  
Antoine Jalil ◽  
...  

Hepatology ◽  
1993 ◽  
Vol 18 (6) ◽  
pp. 1377-1383 ◽  
Author(s):  
Makoto Nakamuta ◽  
Masao Ohashi ◽  
Yuichi Tanabe ◽  
Kaichiro Hiroshige ◽  
Hajime Nawata

1957 ◽  
Vol 190 (1) ◽  
pp. 117-120 ◽  
Author(s):  
John A. Gagnon ◽  
Robert W. Clarke

The excretion of creatinine and para-aminohippurate in five chimpanzees was found to be both by glomerular filtration and tubular secretion with mutual interference between the secretory processes. No evidence was found to suggest that inulin is subject to tubular secretion or reabsorption and it is therefore still acceptable for the measurement of glomerular filtration. The absolute values of glomerular filtration and renal excretion of creatinine and para-aminohippurate may have been modified by the use of anesthesia, but no striking differences are apparent between the kidney of the chimpanzee and that of man. PAH at high plasma concentration increases the excretion of potassium.


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