scholarly journals A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis

2012 ◽  
pp. 1575 ◽  
Author(s):  
Satya Prakash ◽  
MS Wei Shao ◽  
Arghya Paul ◽  
Sana Abbasi ◽  
Parminder Chahal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Sirna Delivery ◽  
Breast Cancer Therapy ◽  
Adeno Associated Virus ◽  
Virus Like Particle ◽  
Vitro Analysis ◽  
In Vitro Analysis

scholarly journals Hydrogel-Mediated DOX⋅HCl/PTX Delivery System for Breast Cancer Therapy

2019 ◽  
Vol 20 (19) ◽  
pp. 4671
Author(s):  
Hoon Hyun ◽  
Young Yoo ◽  
So Kim ◽  
Hyun Ko ◽  
Heung Chun ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Anticancer Effect ◽  
Breast Cancer Therapy ◽  
Glycol Chitosan ◽  
Burst Period ◽  
Delivery Approach ◽  
Dual Drug

We used a hydrogel-mediated dual drug delivery approach, based on an injectable glycol chitosan (GC) hydrogel, doxorubicin hydrochloride (DOX⋅HCl), and a complex of beta-cyclodextrin (β-CD) and paclitaxel (PTX) (GDCP) for breast cancer therapy in vitro and in vivo. The hydrogel was swollen over 3 days and remained so thereafter. After an initial burst period of 7 hours, the two drugs were released in a sustained manner for 7 days. The in vitro cell viability test showed that GDCP had a better anticancer effect than well plate and DOX⋅HCl/PTX (DP). In addition, the in vivo tests, which evaluated the anticancer effect, systemic toxicity, and histology, proved the feasibility of GDCP as a clinical therapy for breast cancer.

scholarly journals An analytical study of Trastuzumab-dendrimer-fluorine drug delivery system in breast cancer therapy in vitro

2021 ◽  
Vol 133 ◽  
pp. 111053
Author(s):  
Dorota Bartusik-Aebisher ◽  
Grzegorz Chrzanowski ◽  
Zuzanna Bober ◽  
David Aebisher
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Analytical Study ◽  
Breast Cancer Therapy

scholarly journals In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e64388 ◽  
Author(s):  
Chanel E. Smart ◽  
Brian J. Morrison ◽  
Jodi M. Saunus ◽  
Ana Cristina Vargas ◽  
Patricia Keith ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Human Breast ◽  
Primary Human Breast ◽  
Vitro Analysis ◽  
In Vitro Analysis

Anti-Her2 single-chain antibody mediated DNMTs-siRNA delivery for targeted breast cancer therapy

2012 ◽  
Vol 161 (3) ◽  
pp. 875-883 ◽  
Author(s):  
Shuang Dou ◽  
Yan-Dan Yao ◽  
Xian-Zhu Yang ◽  
Tian-Meng Sun ◽  
Cheng-Qiong Mao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Sirna Delivery ◽  
Single Chain ◽  
Breast Cancer Therapy ◽  
Single Chain Antibody
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