scholarly journals EVALUATION OF EFFICACY OF DEMINERALIZED FREEZE DRIED BONE ALLOGRAFT WITH AND WITHOUT PLATELET-RICH FIBRIN IN THE TREATMENT OF INTRABONY DEFECTS BY CONE BEAM COMPUTED TOMOGRAPHY: A CLINICAL AND RADIOGRAPHIC STUDY

2021 ◽  
Vol 9 (09) ◽  
pp. 156-164
Author(s):  
Sunkavilli Ravi Kiran ◽  
◽  
Mohd Aijaz Ahmed ◽  
Niharika Bammidi ◽  
Yudheera Karnam ◽  
...  
Keyword(s):  
Bone Allograft ◽  
Cone Beam ◽  
Platelet Rich Fibrin ◽  
Intrabony Defect ◽  
Probing Depth ◽  
Freeze Dried ◽  
Tissue Changes ◽  
Additional Value ◽  
Attachment Level ◽  
Cone Beam Computer Tomography

Background: Eventhough the combination of DFDBA (demineralized freeze dried bone allograft) with PRF (platelet-rich fibrin) has been attempted in periodontal practice with significant results, assessment of the intrabony defect and defect bone fill largely done with two-dimensional imaging modalities. Three dimentional analysis of the intrabony defect and defect bone fill has not been attempted with cone beam computer tomography (CBCT). The present study evaluated the efficacy of DFDBA with and without PRF in the treatment ofintrabony defects by CBCT. Methods: 60 defects in systemically healthy patients ranging from 18 to 50 years of age will be included in the study.30 defects were treated with PRF+DFDBA and 30 defects were treated with DFDBA alone. The study will include the assessment of clinical parameters involving probing depth (PD), relative attachment level(RAL), full mouth bleeding scores(FMBS),plaque index and gingival index from baseline to 3 , 6, 9 months. Hard tissue changes will be assessed radiographically by evaluating defect fill and defect resolution by CBCT at baseline& 9 months. Results: The results of the present study are statistically significant in both groups in terms of clinical and radiographical parameters (P < 0.001). In inter-group comparison, there was a statistically significant greater PD reduction and attachment gain while there was not significant reduction in terms of PI, GI, FMBS, defect fill and defect resolution in DFDBA+ PRF group. Conclusion: DFDBA along with PRF failed to provide additional value in terms of defect fill and defect resolution over DFDBA alone.

scholarly journals Platelet-rich fibrin in combination with decalcified freeze-dried bone allograft for the management of mandibular degree II furcation defect: A randomised controlled clinical trial

2019 ◽  
Vol 39 (01) ◽  
pp. 33-40 ◽  
Author(s):  
Ashish Agarwal ◽  
R. G. Shiva Manjunath ◽  
Priyamwada Sethi ◽  
G. Shiva Shankar
Keyword(s):  
Statistical Significance ◽  
Periodontal Regeneration ◽  
Bone Allograft ◽  
Controlled Clinical Trial ◽  
Hard Tissue ◽  
Platelet Rich Fibrin ◽  
Probing Depth ◽  
Freeze Dried ◽  
Furcation Defects ◽  
Intergroup Comparison

Background: Treatment of furcation involvement of molars with periodontal disease remains challenging and unpredictable. Platelet-rich fibrin (PRF) has received the attention of researchers due to its pleiotropic properties essential for periodontal wound healing. The osteoinductive property of demineralized freeze-dried bone allograft (DFDBA) has been successfully used in periodontal regeneration. Aim: The present study aimed to explore the effectiveness of PRF alone and with DFDBA in the treatment of mandibular degree II furcation defects in subjects with chronic periodontitis. Material and Methods: Patients treated were from the Department of Periodontology and Implantology, Institute of Dental Sciences, Bareilly. A total of 60 mandibular molars were treated with either open flap debridement (OFD) alone, [Formula: see text] combination or [Formula: see text] combination. The soft and hard tissue parameters such as vertical probing depth (VPD), vertical clinical attachment level (VCAL), gingival marginal level (GML), horizontal probing depth (HPD), vertical bone fill (VBF), horizontal bone fill (HBF) and furcation width (FW) were determined at baseline and 9 months postoperatively. A paired [Formula: see text]-test was conducted to assess the statistical significance between time period within each group for clinical and radiographic parameters. ANOVA and post-hoc Tukey’s tests were also conducted for intergroup comparison of soft and hard tissue parameters. Statistical significance was set at [Formula: see text]. Results and Discussion: After 9 months, all treatment groups showed significant ([Formula: see text]) improvement in soft and hard tissue parameters, except GML in all the three groups and HBF and FW in the OFD group as compared to baseline. The mean VBF change was highest in the [Formula: see text] group ([Formula: see text]) mm, followed by that in the [Formula: see text] and OFD groups ([Formula: see text] and [Formula: see text][Formula: see text]mm, respectively). Conclusions: It was shown that both [Formula: see text] and [Formula: see text] combinations were significantly advantageous for the management of mandibular degree II furcation defects. However, the [Formula: see text] combination has significantly greater benefits than [Formula: see text] combination in terms of VBF.

Effects of Mixture of Fibrin-Fibronectin Sealant System and Calcium Carbonate in Periodontal Intrabony Defects

2006 ◽  
Vol 309-311 ◽  
pp. 1397-1400
Author(s):  
Ui Won Jung ◽  
S.J. Chang ◽  
Seong Ho Choi ◽  
C.S. Kim ◽  
Jung Kiu Chai
Keyword(s):  
Calcium Carbonate ◽  
Gingival Recession ◽  
Control Group ◽  
Intrabony Defects ◽  
Clinical Attachment Level ◽  
Intrabony Defect ◽  
Probing Depth ◽  
Group 2 ◽  
Attachment Level ◽  
Experimental Group

This study evaluated the effects of mixture of fibrin-fibronectin sealant system(FFSS) and calcium carbonate(CC) in periodontal intrabony defects. Thirty six sites with two or three wall intrabony defect were used. 14 defects treated with periodontal flap surgery were assigned as the control group. 11 defects treated with CC implantation were designed as experimental group 1 and 11 defects, treated with CC and FFSS implantation as experimental group 2. The control and experimental groups all achieved statistically significant improvements in probing depth and clinical attachment level from the baseline (P<0.01). In mean postsurgery probing depth and gingival recession reduction, there were no statiscally significant differences between the experimental groups and the controls. However, mean postsurgery clinical attachment levels of both experimental groups improved significantly more than that of the controls. As a result, we suggest that mixture of FFSS and CC can be used effectively in intrabony defect as osteoconductive materials.

scholarly journals Treatment of a Developmental Groove and Supernumerary Root Using Guided Tissue Regeneration Technique

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Zahra Alizadeh Tabari ◽  
Hamed Homayouni ◽  
Tahere Pourseyediyan ◽  
Armita Arvin ◽  
Derrick Eiland ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Root Canal ◽  
Combined Treatment ◽  
Bone Allograft ◽  
Guided Tissue Regeneration ◽  
Maxillary Incisor ◽  
Treatment Procedure ◽  
Root Canal Therapy ◽  
Probing Depth ◽  
Freeze Dried

Introduction. The radicular groove is a developmental groove which is usually found on the palatal or lateral aspects of the maxillary incisor teeth. The present case is a maxillary lateral incisor with a small second root and a deep radicular groove. The developmental groove caused a combined periodontal-endodontic lesion. Methods. Case was managed using a combined treatment procedure involving nonsurgical root canal therapy and surgical periodontal treatment. After completion of root canal treatment, guided tissue regeneration (GTR) was carried out using decalcified freeze dried bone allograft (DFDBA) and a bioabsorbable collagenous membrane. Tooth also was splinted for two months. Results. After 12 months the tooth was asymptomatic. The periapical radiolucency disappeared and probing depth did not exceed 3 mm. Conclusion. Combined treatment procedure involving nonsurgical root canal therapy and surgical periodontal regenerative treatment can be a predictable technique in treating combined endodontic-periodontal lesions caused by radicular groove.

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