scholarly journals Experience in organizing screening of thyroid pathology during pregnancy in the region of iodine deficiency

2020 ◽  
pp. 58-64
Author(s):  
A. Z. Bulgakova ◽  
E. A. Fazlyeva ◽  
G. A. Galieva ◽  
R. A. Izmailova
2021 ◽  
Vol 65 (1) ◽  
pp. 37-44
Author(s):  
Konstantin V. Kondrat’ev ◽  
Pavel F. Kiku ◽  
Svetlana N. Beniova ◽  
Marina V. Li ◽  
Ol’ga G. Tsygankova ◽  
...  

Introduction. Iodine deficiency diseases (IDD) are currently one of the most common pathologies of the endocrine system. The development of these diseases in the Primorsky region depends on the sufficient intake of iodine and various factors of exogenous and endogenous nature. The identification and establishment of the contribution of social and hygienic nature factors in the comprehensive impact to the occurrence and development of thyroid diseases, including IDD, is an important area of research. The aim of the study is to obtain information about the social and hygienic factors that influence the occurrence and development of thyroid pathology, including iodine deficiency diseases. Material and methods. Based on statistical data the dynamics in the population prevalence of diseases of the endocrine system in the Primorsky region was analyzed. To identify social and hygienic factors, a survey of 222 patients of the Center of Endocrinology Regional Clinical Hospital No. 2 (Vladivostok) was performed. Statistical processing of the results of the sociological survey was carried out using the Terentyev correlation pleiades method. Results. The development of thyroid pathology, including IDD, is influenced by unfavorable environmental conditions, physical inactivity and stressful situations in the workplace, unfavorable occupational factors including an exposure to noise, dust, radiation from a personal computer, lifestyle factors due to low physical activity, non-compliance with the waking and sleeping regime. More often, thyroid diseases develop in women and people over 50 years of age. The development of IDD is influenced by the observance of the principles of rational nutrition and the presence of certain foods in the diet. The contribution of these factors in the conditions of their combined impact on the human body is established. Conclusion. The identified complex of social and hygienic factors that are important for the occurrence and development of thyroid diseases can be further used to create targeted programs for the prevention of these diseases in the population of the Primorsky region.


2021 ◽  
Vol 67 (2) ◽  
pp. 10-19
Author(s):  
E. A. Troshina ◽  
N. M. Platonova ◽  
E. A. Panfilova

BACKGROUND: The level of iodine consumption by the population largery determines the spectrum of thyroid pathology. To date, in the Russian Federation, iodine-deficiency disorders (IDD) occupy a leading position in the structure of all thyroid diseases. Chronic ID leads to adverse health consequences and significant economic costs for their elimination on a national scale. However, the spectrum of thyroid pathology is not limited to the problem of ID, and the study of other thyroid diseases is also of interest.AIMS: to assess the dynamics of prevalence and incidence of IDD and other thyroid diseases in the entire population of the RF for the period 2009–2018, using official state statistics.MATERIALS AND METHODS: the main epidemiological indicators (incidence and prevalence) of thyroid diseases in the entire population of the RF were analyzed using official state statistics. The analyzed period is 2009–2018. There was no medical intervention. To assess the dynamics of prevalence and incidence, a linear regression models were constructed, the slope of the trend line was calculated.RESULTS: the data were analyzed in accordance with the structure of diseases presented in the statistical reporting: goiter, thyroiditis, hypothyroidism, thyrotoxicosis, congenital iodine deficiency syndrome. For the ten-year period 2009–2018 there is a statistically significant increase in the prevalence of various forms of goiter, thyrotoxicosis, congenital iodine deficiency syndrome in the entire population of the Russian Federation. During the observation period, an increase in the incidence of thyrotoxicosis was revealed. With regard to the incidence of congenital iodine deficiency syndrome, only an upward trend was revealed. Despite the fact that during the observation period the number of new cases of various forms of goiter decreased, the prevalence of goiter among the population of the Russian Federation remains high: 1.2% of the population by January 1, 2019. with the growth of autoimmune pathology, improvement of the level of diagnosis, and also, in some cases, with overdiagnosis (for example, when diagnosing autoimmune thyroiditis in individuals with asymptomatic carriage of antithyroid antibodies). The current approaches to iodine prophylaxis are not effective enough.CONCLUSIONS: the results of the analysis indicate mainly an increase in the high prevalence of thyroid pathology among the population of the RF against the background of regional events. The problem of ID remains unresolved, which dictates the need to introduce universal mandatory salt iodization in the territory of the RF.


1965 ◽  
Vol 48 (1) ◽  
pp. 14-22 ◽  
Author(s):  
S. A. Aboul-Khair ◽  
J. Crooks

ABSTRACT Studies of iodine metabolism have been carried out in 15 pregnant women, 33 cases with sporadic goitre and 11 with thyrotoxicosis. A low plasma inorganic iodine was common to the three groups. In pregnancy and sporadic goitre the thyroid clearance of iodine was elevated and the absolute iodine uptake normal. A high thyroid clearance of iodine in thyrotoxicosis was associated with a high absolute iodine uptake. The results suggest that both pregnancy and sporadic goitre are physiological responses to an iodine deficiency state while the iodine deficiency state of thyrotoxicosis is secondary to increased thyroid activity.


1974 ◽  
Vol 76 (1) ◽  
pp. 67-73 ◽  
Author(s):  
H. Agerbæk ◽  
S. E. Jensen

ABSTRACT In 129 patients with non-toxic goitre and 27 normal controls, thyroid dynamic patterns were estimated in an attempt to elucidate pathogenesis. The clinically euthyroid state was confirmed by measurement of PBI, T3-sephadex uptake and BMR. Thyroid clearance (th. cl.), plasma iodide (PII), and absolute iodine uptake (AIU) were determined and a perchlorate discharge test performed. Twenty patients (16%) had a high AIU and were thus suspected of having dyshormonogenesis; nine were thoroughly investigated and in six dyshormonogenesis was found. Both normals and non-toxic goitre patients had a low PII, but in the goitrous patients values were lowest. The thyroid clearance of iodide was significantly higher in the goitre patients, suggesting iodine deficiency to be a major aetiologic factor for goitre formation. AIU was higher in the goitre patients than in normals, suggesting a larger iodine leakage from the thyroid in these patients.


Sign in / Sign up

Export Citation Format

Share Document