Congenital Iodine Deficiency Hypothyroidism

2020 ◽  
Author(s):  
Keyword(s):  
Iodine Deficiency

A COMPARATIVE STUDY OF IODINE METABOLISM IN PREGNANCY, SPORADIC GOITRE AND THYROTOXICOSIS

1965 ◽  
Vol 48 (1) ◽  
pp. 14-22 ◽  
Author(s):  
S. A. Aboul-Khair ◽  
J. Crooks
Keyword(s):  
Comparative Study ◽  
Pregnant Women ◽  
Iodine Deficiency ◽  
Physiological Responses ◽  
Iodine Uptake ◽  
Thyroid Activity ◽  
Deficiency State ◽  
Iodine Metabolism ◽  
Inorganic Iodine ◽  
In Pregnancy

ABSTRACT Studies of iodine metabolism have been carried out in 15 pregnant women, 33 cases with sporadic goitre and 11 with thyrotoxicosis. A low plasma inorganic iodine was common to the three groups. In pregnancy and sporadic goitre the thyroid clearance of iodine was elevated and the absolute iodine uptake normal. A high thyroid clearance of iodine in thyrotoxicosis was associated with a high absolute iodine uptake. The results suggest that both pregnancy and sporadic goitre are physiological responses to an iodine deficiency state while the iodine deficiency state of thyrotoxicosis is secondary to increased thyroid activity.

QUANTITATIVE STUDIES OF IODINE METABOLISM IN SPORADIC, NON-TOXIC GOITRE

1974 ◽  
Vol 76 (1) ◽  
pp. 67-73 ◽  
Author(s):  
H. Agerbæk ◽  
S. E. Jensen
Keyword(s):  
Iodine Deficiency ◽  
Iodine Uptake ◽  
Quantitative Studies ◽  
Euthyroid State ◽  
Iodine Metabolism ◽  
Dynamic Patterns ◽  
Perchlorate Discharge Test ◽  
Normal Controls ◽  
Discharge Test

ABSTRACT In 129 patients with non-toxic goitre and 27 normal controls, thyroid dynamic patterns were estimated in an attempt to elucidate pathogenesis. The clinically euthyroid state was confirmed by measurement of PBI, T3-sephadex uptake and BMR. Thyroid clearance (th. cl.), plasma iodide (PII), and absolute iodine uptake (AIU) were determined and a perchlorate discharge test performed. Twenty patients (16%) had a high AIU and were thus suspected of having dyshormonogenesis; nine were thoroughly investigated and in six dyshormonogenesis was found. Both normals and non-toxic goitre patients had a low PII, but in the goitrous patients values were lowest. The thyroid clearance of iodide was significantly higher in the goitre patients, suggesting iodine deficiency to be a major aetiologic factor for goitre formation. AIU was higher in the goitre patients than in normals, suggesting a larger iodine leakage from the thyroid in these patients.

Iodine Deficiency in Newborn Sheep and Swine

1948 ◽  
Vol 7 (3) ◽  
pp. 298-310 ◽  
Author(s):  
F. N. Andrews ◽  
C. L. Shrewsbury ◽  
C. Harper ◽  
C. M. Vestal ◽  
L. P. Doyle
Keyword(s):  
Iodine Deficiency

FAKTOR-FAKTOR PENYEBAB GAKY DAN HUBUNGANNYA DENGAN STATUS GIZI ANAK SEKOLAH DASAR NEGERI 36 SINGGALANG TANAH DATAR

2018 ◽  
Vol 8 (2) ◽  
pp. 200
Author(s):  
RAHMITA YANTI
Keyword(s):  
Socioeconomic Status ◽  
Nutritional Status ◽  
Primary School ◽  
Nutrition Education ◽  
Iodine Deficiency ◽  
School Children ◽  
Iodine Intake ◽  
Primary School Children ◽  
Iodine Deficiency Disorder ◽  
P Value

The main nutritional problems facing the Indonesian government one of Iodine deficiency disorders (IDD). West Sumatra province found the prevalence of enlarged adenoids school children is still high which ranges from 12% -44,1% and Total Goiter Rate also high in the coastal region. This study aims to determine the factors cause iodine deficiency disorder (IDD) and relationship to nutritional status of primary school children 36 Singgalang Tanah Datar.This type of research is Case Control. The study population are the all of primary school children 36 Singgalang Tanah Datar, aged 9-12 years who suffered goiter examined palpation. The sample consisted of 30 cases and 30 controls. Sampling was done by purposive sampling technique. Data were processed using univariate, bivariate with chisquare test.The research results revealed there is relationship IDD to nutritional status of primary school children 36 Singgalang Tanah Datar (p = 0,034 (95% CI: 1,2 to 11,4)), an related of iodine intake (p = 0,016 (95% CI: 1,5 -14,4)), goitrogenik intake (p = 0,039 (95% CI: 1,2-9,9)), the quality of salt (p = 0,038 (95% CI: 1,2 to 10,2)), socioeconomic status (p = 0,02 (95% CI: 1,4-11,8), and the level of parents knowledge (p = 0,039 (95% CI: 1,2 to 9,9)) with iodine deficiency disorder. While variable which is not related to iodine deficiency disorder is the parents education level p = 0,77 (p value> 0,05)This study concluded that there is relationship IDD to nutritional status and there are relationship iodine intake, goitrogenik, salt quality, socioeconomic status, and level of knowledge of parent with iodine deficiency disorder. Need for nutrition counseling conducted by the health promotion officers regularly about the importance of the use of iodized salt for children's growth and nutrition education in the family menu processing so as to improve the nutritional status of children at the household levelKeywords : Iodine deficiency disorder, nutritional status, school children

THE INTENSITY OF OXIDATIVE MODIFICATION OF PROTEINS AND PEROXIDATION OF LIPIDS IN THE BLOOD SERUM, BRAIN, LIVER AND PANCREAS TISSUES OF RATS WITH INSULIN RESISTANCE AND CONGENITAL IODINE DEFICIENCY

2019 ◽  
pp. 115-120
Author(s):  
V. B. Stetsevyat ◽  
N. M. Voronych-Semchenko
Keyword(s):  
Insulin Resistance ◽  
Iodine Deficiency ◽  
Thiobarbituric Acid ◽  
Oxidative Modification ◽  
Peroxidation Of Lipids ◽  
Diene Conjugates ◽  
Oxidative Modification Of Proteins ◽  
High Fructose ◽  
Liver And Pancreas ◽  
Dependent Processes

The results of the study about the nature of oxygen-dependent processes in rats that were on a high-fructose diet for 8 weeks under conditions of adequate iodine supply and congenital iodine deprivation is presented in the article. The significant activation of peroxide oxidation of proteins (by increasing the aldo- and keto-derivates of a neutral nature) and lipids (increased of diene conjugates content and products, that are responsible to thiobarbituric acid) of animals with insulin resistance was found. An aggravating factor in the course of these processes is a congenital iodine deficiency. The changes of oxidative modification of proteins in animals with congenital iodine deficiency had multidirectional character, and processes of lipid peroxidation mainly increased. The most pronounced changes of the studied processes were observed in the liver and pancreas of animals with insulin resistance against the background of congenital iodine deficiency.

scholarly journals Factors associated with the consumption of table salt with inadequate iodine concentrations: a population analysis at a Peruvian household level

2021 ◽  
pp. 1-8
Author(s):  
Akram Hernández-Vásquez ◽  
Rodrigo Vargas-Fernández ◽  
Diego Azañedo
Keyword(s):  
Iodine Deficiency ◽  
Mother Tongue ◽  
Population Analysis ◽  
Public Health Problem ◽  
Women Of Childbearing Age ◽  
Table Salt ◽  
Childbearing Age ◽  
Household Level ◽  
Factors Associated ◽  
Salt Iodine

Abstract Objective: Iodine deficiency is a public health problem, especially in Peru, where it affects women of childbearing age and school-age children. The objective of the study was to conduct a household-level analysis of the factors associated with the consumption of table salt with inadequate amounts of iodine in Peru. Design: Analytical cross-sectional study using Peruvian household-level data from the Demographic and Family Health Survey. Table salt iodine concentrations were considered as the dependent variable (‘inadequate’ with iodine levels <30 PPM and ‘adequate’ with levels ≥30 PPM). The association between iodine concentrations in salt and independent variables was evaluated using crude and adjusted log-binomial regression models. Setting: Peru. Participants: A total of 25 007 households were included. Results: In Peru, 21·8 % households had inadequate table salt iodine concentrations. Belonging to the poorer and poorest wealth index, living in the Highlands natural region, and living with women of childbearing age with native mother tongue were identified as factors associated with inadequate iodine concentrations in table salt. Conclusions: There is an urgent need to ensure that table salt with adequate iodine concentrations is available for poor populations, residents of the Highlands and households with ethnic presence. Likewise, it is necessary to promote good storage practices, greater regulation/law enforcement and better monitoring of the companies that manufacture or sell this product. Furthermore, the population needs to be informed of the disorders associated with iodine deficiency.

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