scholarly journals The relation between hepcidin levels and hematologic parameters in cattle with theileriosis

2019 ◽  
Vol 75 (02) ◽  
pp. 6205-2019
Author(s):  
YILDIRAY BASBUGAN ◽  
NAZMI YUKSEK ◽  
OZLEM ORUNC KILINC
Keyword(s):  
Biochemical Parameters ◽  
Statistical Significance ◽  
Control Group ◽  
Cell Distribution ◽  
Distribution Width ◽  
Iron Parameters ◽  
Hematological And Biochemical Parameters ◽  
The Relationship ◽  
Diagnostic Importance ◽  
Red Blood Cell Distribution

This study aimed to determine the relationship between hepcidine levels and some hematological and biochemical parameters after anemia in natural theileriosis cows. This research was conducted with a total of 25 cattle, including 10 healthy controls and 15 cattle with natural theileriosis. 1098 bp positivity was determined according to the PCR result. Leukocyte (WBC), erythrocyte (RBC), hematocrit (HCT) and hemoglobin (HGB) levels were decreased. However, red blood cell distribution width (RDW), Platelet (PLT) and hepcidin levels were increase determined in natural theileriosis cows according to the control group. In addition, a positive correlation was detected between hepsin and iron parameters although there is no statistical significance between them and a negative correlation was determined between hepcidine and HCT, HGB and RDW parameters. As a result, it was determined that erythrocyte parameters decrease and increase in iron parameters and heptidine levels in cattle with theileriosis. It can be concluded that the diagnostic importance.

scholarly journals Correlation of High Sensitive C Reactive Protein Levels as Inflammation Marker with Red Blood Cell Distribution Width Value in Regular Hemodialysis Patients at H. Adam Malik General Hospital

2021 ◽  
Vol 8 (7) ◽  
pp. 14-27
Author(s):  
Anwar Sholeh ◽  
Alwi Thamrin Nasution ◽  
Radar Radius Tarigan
Keyword(s):  
General Hospital ◽  
Pearson Correlation ◽  
Cell Distribution ◽  
C Reactive Protein ◽  
Distribution Width ◽  
Reactive Protein ◽  
Pearson Correlation Analysis ◽  
The Relationship ◽  
Red Blood Cell Distribution ◽  
Regular Hemodialysis

Background: Chronic kidney disease (CKD) is characterized by structural and functional disorder of the kidney with irreversible and gradual characteristics with one of the modalities of renal replacement therapy such as hemodialysis (HD). The role of inflammation in HD patients by uremic toxin and dialysis can be assessed by the marker of High Sensitive C Reactive Protein (HsCRP). Several studies have examined the relationship between HsCRP and red cell distribution width (RDW) in regular HD patients which leads to increase patient morbidity and mortality, but until now, there has been no study in Indonesia regarding the correlation between HsCRP and RDW in regular HD patients. This study aims to determine the correlation HsCRP as a marker of inflammation and RDW values in regular HD patients. Methods: This is a cross-sectional study in Regular HD patients at Dialysis Unit-H. Adam Malik General Hospital. A total of 20 subjects were included. Bivariate and multivariate analysis was conducted to analyze the relationship of HsCRP, ureum, creatinin, hemoglobin, and eGFR to RDW. Results: There were 20 Regular HD patients analyzed. The proportion of patients with increased RDW was 80%. In pearson correlation test, there is a strong correlation between HsCRP and RDW (r= 0.667, p<0.001). Discussion: Majority of regular HD patients at H. Adam Malik General Hospital were assessed with increased RDW. Pearson correlation analysis revealed HsCRP was significantly associated with RDW. Conclusion: Increased RDW was found in 80% of regular HD patients at H. Adam malik General Hospital. From pearson correlation analysis, we found HsCRP was significantly associated with RDW. Keywords: inflammation, high sensitive c reactive protein, red blood cell distribution width, regular hemodialysis.

Nonspecific Chronic Low Back Pain in Elderly Patients

2021 ◽  
pp. 34
Author(s):  
Amal Mowafy
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Muscle Mass ◽  
Control Group ◽  
P Value ◽  
Low Back ◽  
Cell Distribution ◽  
Distribution Width ◽  
X Ray ◽  
Red Blood Cell Distribution

Introduction: Low back pain is one of the most common causes of disabilities in old people often due to lumber degeneration (osteoarthritis) and spinal canal stenosis. In our study, we determine the prevalence and associated changes of low back pain that increase with age. Methodology: This observational cohort study was carried out from March 2019 to March 2021 at the El-Moussenin Center in Port Said. The study included 300 patients aged ≥65 years with a chronic nonspecific low back pain for at least six months, a Visual Analogue Scale (VAS) score of 3 and more, and an absence of spinal pathology such as infection, tumor, fracture, spondylolisthesis, or spinal degeneration of grade 2 and above. Patients were divided into two groups: (i) a study group including patients with a mean age of 75 years with nonspecific chronic LBP (n = 150) and (ii) an age- and sex-matched control group (n = 150) with no chronic low back pain using propensity score-matched analysis. All patients underwent whole spinal X-ray, lumbar MRI, CBC, and DXA. Result: We analyzed laboratory finding, radiological finding for global spinal parameter, and lumber degeneration body composition analysis using whole body dual energy X-ray absorptiometry. We found increase in red blood cell distribution width (it is an index of aging), it was higher in geriatric with CLBP (32) and in control (6.9) with a p-value < 0.001. Skeletal muscle mass index was 6.23 ± 0.92 in the studied group and 6.43 ± 1.02 in the control group with a p-value = 0.045. Increase in fat mass was noted in both the studied (32.17 ± 7.07) and the control (29.28 ± 7.48) groups with a p-value < 0.001. Moreover, those patients had lower lumbar lordosis, higher sagittal vertical axis regarding decrease in muscle mass in trunk and extremities. Conclusion: Red blood cell distribution width which is a sign of aging was high in geriatric group with CLBP. Moreover, geriatric CLBP is often associated with osteoporosis which affects the pain threshold and triggers CLBP due to age-related loss of skeletal muscle mass and spinal sagittal malalignment.

Sign in / Sign up

Export Citation Format

Share Document