scholarly journals Right ventricular crypts in a myocardial bridge: Relevance to surgical relief

2020 ◽  
Vol 2019 (3) ◽  
Author(s):  
Magdi Yacoub ◽  
Mohamed Nagy ◽  
Hatem Hosny ◽  
Ramy Doss ◽  
Ahmed Afifi ◽  
...  
Keyword(s):  
Heart Disease ◽  
Coronary Artery ◽  
Multimodality Imaging ◽  
Hypertensive Heart Disease ◽  
Myocardial Bridge ◽  
Normal Individuals ◽  
Before And After ◽  
Thin Walled ◽  
The Right ◽  
First Time

Crypts are very thin walled invaginations from the cavity of the left ventricle into the compact myocardium. With the advent and increased application of multimodality imaging, crypts are being increasingly identified in both normal individuals and patients, with various conditions including HCM, before and after the development of LV hypertrophy, LV non-compaction and hypertensive heart disease. to date crypts have not been described in the right ventricle. We here describe for the first time, RV crypts which were extending into a myocardial bridge, in a patient with HCM and dynamic obstruction of the LAD coronary artery. We also document and discuss the serious complications which can arise from crypts, and highlight the importance of preoperative identification of crypts. Further studies are required to determine the fetal origin of crypts and their clinical significance

Efferent vagal innervation of canine ventricle

1985 ◽  
Vol 248 (1) ◽  
pp. H89-H97 ◽  
Author(s):  
N. Takahashi ◽  
M. J. Barber ◽  
D. P. Zipes
Keyword(s):  
Coronary Artery ◽  
Vagal Stimulation ◽  
Left Ventricular ◽  
Constant Infusion ◽  
Epicardial Surface ◽  
Before And After ◽  
Vagal Innervation ◽  
The Subject ◽  
Infusion Of Norepinephrine ◽  
The Right

The route efferent vagal fibers travel to reach the left ventricle is not clear and was the subject of this investigation. We measured left ventricular and septal effective refractory period (ERP) changes during vagal stimulation and a constant infusion of norepinephrine, before and after phenol was applied at selected sites of the heart to interrupt efferent vagal fibers that may be traveling in that area. Phenol applied to the atrioventricular (AV) groove between the origin of the right coronary artery anteriorly to the posterior descending branch of the circumflex coronary artery completely eliminated vagal-induced prolongation of ERP in the anterior and posterior left ventricular free wall and reduced, but did not eliminate, ERP prolongation in the septum. A large (3-cm radius) epicardial circle of phenol prevented vagal-induced ERP prolongation within the circle in all dogs, while a small (1-cm radius) epicardial circle of phenol failed to prevent vagal-induced ERP changes within the circle in any dog. An intermediate (2-cm radius) circle eliminated vagal effects on ERP in 13 of 18 dogs. Arcs of phenol, to duplicate the upper portion of the circle, applied sequentially from apex to base eliminated efferent vagal effects only when painted near or at the AV groove. We conclude that the majority of efferent vagal fibers enroute to innervate the anterior and posterior left ventricular epicardium cross the AV groove within 0.25-0.5 mm (depth of phenol destruction) of the epicardial surface.(ABSTRACT TRUNCATED AT 250 WORDS)

Myocardial bridge over the right coronary artery in man

1989 ◽  
Vol 11 (4) ◽  
pp. 271-273 ◽  
Author(s):  
A. J. C. Bezerra ◽  
L. J. A. DiDio ◽  
L. Piva
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Myocardial Bridge ◽  
The Right

scholarly journals Creating Colored Letters: Familial Markers of Grapheme–Color Synesthesia in Parietal Lobe Activation and Structure

2017 ◽  
Vol 29 (7) ◽  
pp. 1239-1252 ◽  
Author(s):  
Olympia Colizoli ◽  
Jaap M. J. Murre ◽  
H. Steven Scholte ◽  
Romke Rouw
Keyword(s):  
Parietal Lobe ◽  
Diffusion Tensor ◽  
Brain Connectivity ◽  
Brain Activation ◽  
Angular Gyrus ◽  
Group Differences ◽  
The Family ◽  
Before And After ◽  
The Right ◽  
First Time

Perception is inherently subjective, and individual differences in phenomenology are well illustrated by the phenomenon of synesthesia (highly specific, consistent, and automatic cross-modal experiences, in which the external stimulus corresponding to the additional sensation is absent). It is unknown why some people develop synesthesia and others do not. In the current study, we tested whether neural markers related to having synesthesia in the family were evident in brain function and structure. Relatives of synesthetes (who did not have any type of synesthesia themselves) and matched controls read specially prepared books with colored letters for several weeks and were scanned before and after reading using magnetic resonance imaging. Effects of acquired letter–color associations were evident in brain activation. Training-related activation (while viewing black letters) in the right angular gyrus of the parietal lobe was directly related to the strength of the learned letter–color associations (behavioral Stroop effect). Within this obtained angular gyrus ROI, the familial trait of synesthesia related to brain activation differences while participants viewed both black and colored letters. Finally, we compared brain structure using voxel-based morphometry and diffusion tensor imaging to test for group differences and training effects. One cluster in the left superior parietal lobe had significantly more coherent white matter in the relatives compared with controls. No evidence for experience-dependent plasticity was obtained. For the first time, we present evidence suggesting that the (nonsynesthete) relatives of grapheme–color synesthetes show atypical grapheme processing as well as increased brain connectivity.

scholarly journals Multimodality imaging of a hairpin-like coronary fistula between the right coronary artery and the coronary sinus

2021 ◽  
Vol 28 (3) ◽  
pp. 496-497
Author(s):  
Yuan Peng ◽  
Yali Yang ◽  
Yuman Li ◽  
Ziming Zhang ◽  
Lin He ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Coronary Sinus ◽  
Multimodality Imaging ◽  
Coronary Fistula ◽  
The Right

scholarly journals Aspirin Resistance as a Result of Impaired Interaction of Platelets and Neutrophils in Patients with Coronary Heart Disease

2021 ◽  
Vol 17 (1) ◽  
pp. 16-22
Author(s):  
M. D. Goncharov ◽  
A. A. Savchenko ◽  
Yu. I. Grinshtein ◽  
I. I. Gvozdev ◽  
A. A. Kosinova ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Superoxide Radical ◽  
Maximum Intensity ◽  
Control Group ◽  
Platelet Activity ◽  
Before And After ◽  
Artery Disease ◽  
The Relationship

Aim. To study the relationship between the levels of synthesis of reactive oxygen species (ROS) by platelets and neutrophils in patients with coronary heart disease (CHD) before and after coronary artery bypass grafting (CABG), depending on sensitivity to acetylsalicylic acid (ASA).Material and methods. The study included 95 patients with coronary artery disease who are indicated for CABG surgery. The control group consisted of 30 healthy donors. The antiplatelet therapy was stopped for at least 5 days before CABG. In the postoperative period, from the first day, all patients were received 100 mg of an enteric form of acetylsalicylic acid (ASA). Resistance to ASA was determined at the level of platelet aggregation with arachidonic acid ≥20% by optical agregometry at least at one observation point: before CABG, on 1-3 day and on 8-10 day after surgery. We evaluated the spontaneous and induced lucigenin-dependent chemiluminescence (CL) of platelets (ADP induction) and neutrophils (zymosan induction) by the exit time to maximum intensity (Tmax), maximum intensity (Imax) and area (S) under the CL curve.Results. 70.5% sensitive (sASA) and 29.5% resistant (rASA) to ASA patients were revealed. Prior to CABG, in sASA patients, the Imax of spontaneous and zymosan-induced neutrophil CL and CL platelet activity was increased relative to control values. Tmax of spontaneous platelet CL, Imax and S under the ADP-induced platelet CL curve were lower in sASA patients, if to compare with rASA patients. On the 1st and 8-10th day after CABG in sASA patients, the CL indicators of neutrophil and platelet activity also remained elevated compared to control values. On the 1st day after CABG decreased levels of S under the spontaneous CL curve of neutrophils in rASA patients was established compared with sASA patients, and increased levels of Imax and S under the curve of induced neutrophil CL were detected in comparison with the control range. In rASA patients, the values of Tmax of spontaneous platelet CL decreased in relation to the values detected in the control group and sASA patients. On the 8–10th day after CABG, most indicators of spontaneous and zymosan-induced CL neutrophils in rASA patients were also increased compared to control values. In rASA patients a positive correlation of Imax-induced CL was found (r=0.83) on the 1st day after CABG and negative correlations of Tmax of spontaneous CL (r=- 0.75) and S under the curve induced CL (r=-0.70) on the 8-10th day were detected between platelets and neutrophils.Conclusion. In sASA patients with coronary heart disease before and after CABG, a high level of synthesis of superoxide radical by neutrophils and platelets was detected. The relationship between the levels of the synthesis of superoxide radical by neutrophils and platelets was found only after CABG in rASA patients. Increased synthesis of superoxide radical due to metabolic and regulatory relationships in neutrophils and platelets stimulates pro-inflammatory processes in coronary artery disease and determines the sensitivity of platelets to ASA.

Ventricular septal defect with anomalous origin of the left descending coronary artery from the right sinus of Valsava and an intraseptal course

2021 ◽  
pp. 021849232110470
Author(s):  
Guillaume Carles ◽  
Marianne Peyre ◽  
Alexia Dabadie ◽  
Loïc Macé ◽  
Marien Lenoir
Keyword(s):  
Congenital Heart Disease ◽  
Cardiac Surgery ◽  
Heart Disease ◽  
Coronary Artery ◽  
Ventricular Septal Defect ◽  
Congenital Heart ◽  
Septal Defect ◽  
The Right ◽  
Coronary Compression ◽  
Anatomic Result

Patients with anomalous aortic origin of the left anterior descending coronary artery (AAOCA) from the right sinus of Valsava, and associated with a trans-septal course, are recommended for surgery only when symptoms of ischemia are present. The transconal unroofing method is straightforward and provides good anatomic result. In absence of significant coronary compression, surgical management of the trans-septal coronary course is proposed if the patient is a candidate to cardiac surgery for another reason, such as congenital heart disease. We describe a transconal approach in a patient with a trans-septal coronary artery and a ventricular septal defect.

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