scholarly journals The protective effect of Nigella Sativa oil on Penconazole induced -renal toxicity in adult albino rats: Histological, Immunohistochemical and Biochemical study

2019 ◽  
Vol 42 (1) ◽  
pp. 99-120
Author(s):  
nadia badawy khair ◽  
Nermeen Nooreldien
Keyword(s):  
Protective Effect ◽  
Renal Toxicity ◽  
Biochemical Study ◽  
Nigella Sativa ◽  
Albino Rats ◽  
Nigella Sativa Oil

scholarly journals Effect of Nigella sativa against cisplatin induced nephrotoxicity in rats

2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Amnah M.A. Alsuhaibani
Keyword(s):  
Vitamin D ◽  
Seed Treatment ◽  
Mineral Content ◽  
Renal Toxicity ◽  
Nigella Sativa ◽  
Bioactive Components ◽  
Sprague Dawley ◽  
Nigella Sativa Oil ◽  
Sprague Dawley Rats ◽  
Nigella Sativa Seed

In this study, the gross composition and mineral content of Nigella sativa seed powder (NSP) and fatty acid composition of Nigella sativa oil (NSO) were investigated. The ability of NSP, extract (NSE) and NSO in reducing the effects of cisplatin-induced renal toxicity in Sprague-Dawley rats were examined. The obtained results showed that NSP contains high amounts of carbohydrates, protein, and fiber while NSO has higher amounts of linoleicacid, oleic acid, and myristic acid. Rats treated with NSP, NSO, and NSE exhibitedreducedserum levels of urea, creatinine, and potassium, and a significant increase of Na, Na/K, vitamin D, nutritional markers, and antioxidant enzymes compared to the cisplatin-induced renal toxicity group receiving no Nigella sativa seed treatment. This study determined that all powder, oil, and extracts of N. sativa contain potent bioactive components that may aid in treatment against cisplatininduced renal toxicity in rats.

Protective effect of Nigella sativa oil on cisplatin induced nephrotoxicity and oxidative damage in rat kidney

2017 ◽  
Vol 85 ◽  
pp. 7-15 ◽  
Author(s):  
Zeba Farooqui ◽  
Faizan Ahmed ◽  
Sana Rizwan ◽  
Faaiza Shahid ◽  
Aijaz Ahmed Khan ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Protective Effect ◽  
Nigella Sativa ◽  
Rat Kidney ◽  
Nigella Sativa Oil
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