scholarly journals RELATIONSHIP BETWEEN FATIGUE AND FUNCTIONAL STATUS OF THE ELDERLY PATIENTS ON HEMODIALYSIS

2017 ◽  
Vol 4 (2) ◽  
pp. 83-96
Author(s):  
Mohamed Abd-Rabouh ◽  
Soad Abd Elhameed ◽  
Amany Shebl
Author(s):  
Juan F Macias-Nunez ◽  
Javier Deira ◽  
Miguel A Suarez ◽  
Laura Piquero ◽  
Carlos G Musso

Author(s):  
Samuel A. Ajayi ◽  
Lawrence A. Adebusoye ◽  
Adetola M. Ogunbode ◽  
Joshua O. Akinyemi ◽  
Ayodeji M. Adebayo

Background: Assessing the functional status of elderly patients is central in measuring their health outcome. Little is known about the functional status of elderly patients attending our primary care clinic in Nigeria.Objective: To assess the correlates of functional status in elderly patients presenting at the General Outpatient Clinic of the University College Hospital, Ibadan, Nigeria.Method: A cross-sectional study of 360 randomly selected patients aged 60 years and above was undertaken to assess their functional status by scoring their basic activities of daily living (BADL) using the Modified Bathel Index. An interviewer-administered questionnaire was used to obtain the socio-demographic data, anthropometric measurements and morbidities of each patient.Results: The mean age was 69.1 ± 6.6 years with a female-to-male ratio of 1.9: 1. The prevalence of overall functional disability (defined as when assistance was sought in the performance of at least one of the components of BADL) was 88.3%. The highest prevalence of functionaldisability was experienced in the area of personal hygiene and grooming (95.3%) and transferring from bed to chair (95.3%). Overall functional disability significantly increasedwith increasing age (χ2 for trend=14.004, p < 0.0001), living in a polygamous family unit (p = 0.025), and lack of formal education (p = 0.020).Conclusion: Functional disability was high amongst the elderly in this setting. Age, education, and living in a polygamous type of family unit had significant influence on the functional status. High premium should, therefore, be placed on considering these factors in reducing functional disability in the elderly.


2005 ◽  
Vol 23 (28) ◽  
pp. 6865-6872 ◽  
Author(s):  
Paolo Maione ◽  
Francesco Perrone ◽  
Ciro Gallo ◽  
Luigi Manzione ◽  
FrancoVito Piantedosi ◽  
...  

Purpose To study the prognostic value for overall survival of baseline assessment of functional status, comorbidity, and quality of life (QoL) in elderly patients with advanced non—small-cell lung cancer treated with chemotherapy. Patients and Methods Data from 566 patients enrolled onto the phase III randomized Multicenter Italian Lung Cancer in the Elderly Study (MILES) study were analyzed. Functional status was measured as activities of daily living (ADL) and instrumental ADL (IADL). The presence of comorbidity was assessed with a checklist of 33 items; items 29 and 30 of the European Organisation for Research and Treatment of Cancer (EORTC) core questionnaire QLQ-C30 (EORTC QLQ-C30) were used to estimate QoL. ADL was dichotomized as none versus one or more dependency. For IADL and QoL, three categories were defined using first and third quartiles as cut points. Comorbidity was summarized using the Charlson scale. Analysis was performed by Cox model, and stratified by treatment arm. Results Better values of baseline QoL (P = .0003) and IADL (P = .04) were significantly associated with better prognosis, whereas ADL (P = .44) and Charlson score (P = .66) had no prognostic value. Performance status 2 (P = .006) and a higher number of metastatic sites (P = .02) also predicted shorter overall survival. Conclusions Pretreatment global QoL and IADL scores, but not ADL and comorbidity, have significant prognostic value for survival of elderly patients with advanced non—small-cell lung cancer who were treated with chemotherapy. Using these scores in clinical practice might improve prognostic prediction for treatment planning.


2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Chantal Mayer ◽  
Jean-François Morin

Despite the growing number of elderly patients undergoing coronary artery bypass graft (CABG) surgery, no study addressing postoperative outcome from the perspective of preoperative functional status has been reported to date. The present investigation therefore undertook to determine, among elderly individuals matched for cardiac status, whether patients with poor functional status have a greater risk of mortality and morbidity following CABG surgery than those with good functional status. Retrospective preoperative and postoperative geriatric functional assessment using a standardized questionnaire was performed on 46 consecutive patients who had undergone CABG in 1994 at age 65 or older. Preoperative functional status was comprised of pre-anginal functional status (before angina limited physical activity) and anginal functional status (during which angina was a noticeable limiting factor). CABG outcome was recorded in terms of postoperative assessment of functional status, morbidity, and mortality. The results of statistical analysis revealed that both pre-anginal and anginal functional status were sensitive predictors of post-operative functional status (p < 0.005 and p < 0.001, respectively). In addition, the presence of comorbidities typically used in the screening of candidates was found to be a sensitive predictor of outcome (p < 0.02). However, the presence of comorbidities was not significantly linked to poor preoperative functional status (p > 0.05), indicating that these two predictors may screen for different elderly sub-populations at high risk for negative outcome of CABG. If confirmed by further studies of elderly patients undergoing CABG, these results suggest a new and important role for functional status as a predictor of CABG outcome in the elderly. Furthermore, these results may be useful toward the development of a reliable tool in screening for high risk of poor outcome among elderly candidates for CABG surgery. 


2006 ◽  
Vol 5 (1) ◽  
pp. 25-26
Author(s):  
R VIDALPEREZ ◽  
E ABUASSI ◽  
M PARAMODEVEGA ◽  
P VELOSO ◽  
A VARELAROMAN ◽  
...  

MedPharmRes ◽  
2019 ◽  
Vol 3 (3) ◽  
pp. 1-6
Author(s):  
Truc Phan ◽  
Tram Huynh ◽  
Tuan Q. Tran ◽  
Dung Co ◽  
Khoi M. Tran

Introduction: Little information is available on the outcomes of R-CHOP (rituximab with cyclophosphamide, doxorubicin, vincristine and prednisone) and R-CVP (rituximab with cyclophosphamide, vincristine and prednisone) in treatment of the elderly patients with non-Hodgkin lymphoma (NHL), especially in Vietnam. Material and methods: All patients were newly diagnosed with CD20-positive non-Hodgkin lymphoma (NHL) at Blood Transfusion and Hematology Hospital, Ho Chi Minh city (BTH) between 01/2013 and 01/2018 who were age 60 years or older at diagnosis. A retrospective analysis of these patients was perfomed. Results: Twenty-one Vietnamese patients (6 males and 15 females) were identified and the median age was 68.9 (range 60-80). Most of patients have comorbidities and intermediate-risk. The most common sign was lymphadenopathy (over 95%). The proportion of diffuse large B cell lymphoma (DLBCL) was highest (71%). The percentage of patients reaching complete response (CR) after six cycle of chemotherapy was 76.2%. The median follow-up was 26 months, event-free survival (EFS) was 60% and overall survival (OS) was 75%. Adverse effects of rituximab were unremarkable, treatment-related mortality accounted for less than 10%. There was no difference in drug toxicity between two regimens. Conclusions: R-CHOP, R-CVP yielded a good result and acceptable toxicity in treatment of elderly patients with non-Hodgkin lymphoma. In patients with known cardiac history, omission of anthracyclines is reasonable and R-CVP provides a competitive complete response rate.


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