scholarly journals Brain Tumors Detection By Using Convolutional Neural Networks and Selection of Thresholds By Histogram Selection

2021 ◽  
Vol 14 (2) ◽  
pp. 83-89
Author(s):  
Kasiful Aprianto

Brain tumors in medical images have a high diversity in terms of shape and size. Some of the data found a form between the tumor tissue and normal tissue, whereas knowing the tumor’s profile and characteristics becomes a crucial part of searching. By using machine learning capabilities, where machines are given several variables and provide decisions to a certain degree, they have broadly given decisions that support subject matter in making decisions. This study applies the threshold selection method using histogram selection on CT scan data, while the appropriate threshold selection method selects the tumor position accordingly. Furthermore, the Convolutional Neural Network (CNN) is used to classify whether the selected image is a tumor or not. Using CT scan data and calculated experiments, this algorithm can finally be approved and given a brain classification with an accuracy of 75.42 percent.

2018 ◽  
Author(s):  
Rebecca Menlove ◽  
◽  
Randall B. Irmis ◽  
Geoffrey Leonard ◽  
Todd Green ◽  
...  
Keyword(s):  
Ct Scan ◽  

Author(s):  
J Stephen Nix ◽  
Cristiane M Ida

Abstract Molecular testing has become part of the routine diagnostic workup of brain tumors after the implementation of integrated histomolecular diagnoses in the 2016 WHO classification update. It is important for every neuropathologist to be aware of practical preanalytical, analytical, and postanalytical factors that impact the performance and interpretation of molecular tests. Prior to testing, optimizing tumor purity and tumor amount increases the ability of the molecular test to detect the genetic alteration of interest. Recognizing basic molecular testing platform analytical characteristics allows selection of the optimal platform for each clinicopathological scenario. Finally, postanalytical considerations to properly interpret molecular test results include understanding the clinical significance of the detected genetic alteration, recognizing that detected clinically significant genetic alterations are occasionally germline constitutional rather than somatic tumor-specific, and being cognizant that recommended and commonly used genetic nomenclature may differ. Potential pitfalls in brain tumor molecular diagnosis are also discussed.


Author(s):  
Kai Xie ◽  
Yunjing Cui ◽  
Chunlin Wang ◽  
Gan Cui ◽  
Guanqin Wang ◽  
...  

1995 ◽  
Vol 2 (6) ◽  
pp. 444-448 ◽  
Author(s):  
Chang-Heon Woo ◽  
Soo-Yong Kim

ACS Omega ◽  
2021 ◽  
Author(s):  
Jorge Corona-Castuera ◽  
Daniela Rodriguez-Delgado ◽  
John Henao ◽  
Juan Carlos Castro-Sandoval ◽  
Carlos A. Poblano-Salas

2021 ◽  
pp. 1-18
Author(s):  
Andres Gonzalez ◽  
Zoya Heidari ◽  
Olivier Lopez

Summary Core measurements are used for rock classification and improved formation evaluation in both cored and noncored wells. However, the acquisition of such measurements is time-consuming, delaying rock classification efforts for weeks or months after core retrieval. On the other hand, well-log-based rock classification fails to account for rapid spatial variation of rock fabric encountered in heterogeneous and anisotropic formations due to the vertical resolution of conventional well logs. Interpretation of computed tomography (CT) scan data has been identified as an attractive and high-resolution alternative for enhancing rock texture detection, classification, and formation evaluation. Acquisition of CT scan data is accomplished shortly after core retrieval, providing high-resolution data for use in petrophysical workflows in relatively short periods of time. Typically, CT scan data are used as two-dimensional (2D) cross-sectional images, which is not suitable for quantification of three-dimensional (3D) rock fabric variation, which can increase the uncertainty in rock classification using image-based rock-fabric-related features. The methods documented in this paper aim to quantify rock-fabric-related features from whole-core 3D CT scan image stacks and slabbed whole-core photos using image analysis techniques. These quantitative features are integrated with conventional well logs and routine core analysis (RCA) data for fast and accurate detection of petrophysical rock classes. The detected rock classes are then used for improved formation evaluation. To achieve the objectives, we conducted a conventional formation evaluation. Then, we developed a workflow for preprocessing of whole-core 3D CT-scan image stacks and slabbed whole-core photos. Subsequently, we used image analysis techniques and tailor-made algorithms for the extraction of image-based rock-fabric-related features. Then, we used the image-based rock-fabric-related features for image-based rock classification. We used the detected rock classes for the development of class-based rock physics models to improve permeability estimates. Finally, we compared the detected image-based rock classes against other rock classification techniques and against image-based rock classes derived using 2D CT scan images. We applied the proposed workflow to a data set from a siliciclastic sequence with rapid spatial variations in rock fabric and pore structure. We compared the results against expert-derived lithofacies, conventional rock classification techniques, and rock classes derived using 2D CT scan images. The use of whole-core 3D CT scan image-stacks-based rock-fabric-related features accurately captured changes in the rock properties within the evaluated depth interval. Image-based rock classes derived by integration of whole-core 3D CT scan image-stacks-based and slabbed whole-core photos-based rock-fabric-related features agreed with expert-derived lithofacies. Furthermore, the use of the image-based rock classes in the formation evaluation of the evaluated depth intervals improved estimates of petrophysical properties such as permeability compared to conventional formation-based permeability estimates. A unique contribution of the proposed workflow compared to the previously documented rock classification methods is the derivation of quantitative features from whole-core 3D CT scan image stacks, which are conventionally used qualitatively. Furthermore, image-based rock-fabric-related features extracted from whole-core 3D CT scan image stacks can be used as a tool for quick assessment of recovered whole core for tasks such as locating best zones for extraction of core plugs for core analysis and flagging depth intervals showing abnormal well-log responses.


2021 ◽  
Vol 66 (12) ◽  
pp. 718-721
Author(s):  
Larisa Mikhailovna Obukhova ◽  
I. A. Medyanik ◽  
K. N. Kontorshchikova ◽  
S. A. Simagina ◽  
L. T. Musaelyan ◽  
...  

It has been established that the non-neuronal cholinergic system is related to the oncogenesis which increases the attractiveness of its components as the promising markers of oncologic diseases. The purpose of this work is to evaluate the clinical significance of the analysis of the activity of acetyl cholinesterase as a new marker of gliomas. The activity of acetyl cholinesterase was assessed by photo colorimetric analysis according to the Hestrin method recalculating the activity of the enzyme in the tumor tissue per 1 g of protein, and in the blood - by 0.1 g of hemoglobin. The data obtained in the primary tumors of the brain (28) in the tissue of the brain of persons who died as a result of injury (6) and in whole blood of patients with gliomas (28) and practically healthy people (10) were compared with the use of a number of statistical programs. A significant decrease in the activity of acetyl cholinesterase in tumor tissue and in whole blood is revealed as the degree of anaplasia of tumors increases, starting with Grade II. It is for the first time that a significant direct correlation was noted showing the consistency between the decrease in the activity of acetyl cholinesterase in the tumor tissue of the brain and blood. Bioinformatic analysis showed the connection of the enzyme of acetyl cholinesterase with proteins of the PI3K-AKT and Notch signaling pathways providing antiapoptotic and proliferative effects. The found dependences provide new insights into understanding of the mechanisms of gliomas genesis and can be used for selection of new diagnostic markers of brain tumors.


Author(s):  
V. Anastassopoulos ◽  
G. A. Lampropoulos ◽  
A. Drosopoulos ◽  
M. Rey

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