Inhibin-B Levels in Healthy Young Adult Men and Prepubertal Boys: Is Obesity the Cause for the Contemporary Decline in Sperm Count Because of Fewer Sertoli Cells?

2006 ◽  
Vol 27 (4) ◽  
pp. 560-564 ◽  
Author(s):  
S. J. Winters
Keyword(s):  
Young Adult ◽  
Sertoli Cells ◽  
Sperm Count ◽  
Inhibin B ◽  
Healthy Young Adult ◽  
Adult Men ◽  
Prepubertal Boys

scholarly journals Ethnicity, Smoking and Body Composition Influence Testosterone and Estradiol Levels in Healthy Young Adult Men in Malaysia: A Pilot Study

2012 ◽  
Vol 10 (1) ◽  
pp. 404-410 ◽  
Author(s):  
Kok Yong Chin ◽  
Ima Nirwana Soelaiman ◽  
Isa Naina Mohamed ◽  
Hanapi Johari ◽  
Wan Zurinah Wan Ngah
Keyword(s):  
Body Composition ◽  
Young Adult ◽  
Pilot Study ◽  
Healthy Young Adult ◽  
Adult Men ◽  
Estradiol Levels

scholarly journals Cardiorespiratory Fitness and Metabolic Markers in Healthy Young Adult Men

2011 ◽  
Vol 23 (6) ◽  
pp. 845-849 ◽  
Author(s):  
Chiaki Yagura ◽  
Noboru Takamura ◽  
Yoshinobu Goto ◽  
Hajime Sugihara ◽  
Takeshi Sota ◽  
...  
Keyword(s):  
Young Adult ◽  
Cardiorespiratory Fitness ◽  
Healthy Young Adult ◽  
Metabolic Markers ◽  
Adult Men

Resting cardiac energy metabolism is inversely associated with heart rate in healthy young adult men

2011 ◽  
Vol 162 (1) ◽  
pp. 136-141 ◽  
Author(s):  
Gabriele Fragasso ◽  
Francesco De Cobelli ◽  
Roberto Spoladore ◽  
Antonio Esposito ◽  
Anna Salerno ◽  
...  
Keyword(s):  
Heart Rate ◽  
Energy Metabolism ◽  
Young Adult ◽  
Healthy Young Adult ◽  
Adult Men ◽  
Cardiac Energy Metabolism ◽  
Cardiac Energy

Comparison of scapular upward rotator muscle activities and activity ratios during three scapular upward rotator strengthening exercises

2021 ◽  
pp. 1-8
Author(s):  
Jun-Hee Kim ◽  
Oh-Yun Kwon ◽  
Ui-Jae Hwang ◽  
Sung-Hoon Jung ◽  
Sun-Hee Ahn ◽  
...  
Keyword(s):  
Young Adult ◽  
Moderate Intensity ◽  
Serratus Anterior ◽  
Healthy Young Adult ◽  
Adult Men ◽  
Muscle Imbalance ◽  
Upper Trapezius ◽  
Strengthening Exercises ◽  
Activity Ratios ◽  
Lower Trapezius

BACKGROUND: The focus of exercises for restoring the imbalance between scapular upward rotator muscles – upper trapezius (UT), serratus anterior (SA), and lower trapezius (LT) – commonly aims to increase SA and LT activities while not increasing UT activity. OBJECTIVES: The purpose of this study was to compare the activity of the UT, SA, and LT muscles during scapation and protraction exercises, which are two traditional exercises, and during a newly designed scapular upward rotation (SUR) exercise. METHODS: A total of 29 healthy young adult men performed all three exercises with maximum isometric contraction. The electromyographic activities of the UT, SA, and LT were recorded. RESULTS: UT demonstrated the highest activity during scapation. SA activity was the lowest during protraction. However, no difference was found in SA activity during the performance of scapation and SUR. The SA/UT ratio was the highest during scapation. CONCLUSIONS: SUR is a new exercise that can be performed at moderate intensity for shoulder rehabilitation to restore scapular upward rotator muscle imbalance.

scholarly journals Serum inhibin B, FSH, LH and testosterone levels before and after human chorionic gonadotropin stimulation in prepubertal boys with cryptorchidism

2002 ◽  
Vol 147 (1) ◽  
pp. 95-101 ◽  
Author(s):  
P Christiansen ◽  
AM Andersson ◽  
NE Skakkebaek ◽  
A Juul
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Sertoli Cells ◽  
Cell Function ◽  
Serum Levels ◽  
Inhibin B ◽  
Seminiferous Tubules ◽  
Bilateral Cryptorchidism ◽  
Prepubertal Boys ◽  
Baseline Levels

BACKGROUND: Several studies have indicated that cryptorchidism is associated with degenerative changes in both Sertoli cells and germ cells. The gonadal peptide hormone inhibin B reflects Sertoli cell function. Low inhibin B levels are found in a large portion of formerly cryptorchid men who show compromised seminiferous tubule function. It is not known if inhibin B can be used to demonstrate early damage of seminiferous tubules in prepubertal boys with cryptorchidism. METHODS: We investigated the relationship between serum levels of inhibin B, testosterone, FSH and LH in 62 prepubertal boys with uni- and bilateral cryptorchidism. Furthermore, we investigated the changes in serum levels of inhibin B and the corresponding changes in serum levels of FSH, LH and testosterone during a short course (3 weeks) of human chorionic gonadotropin (hCG) injections in 18 of these cryptorchid boys. RESULTS: In the 62 prepubertal boys with uni- or bilateral cryptorchidism there were no significant differences in baseline levels (median and range) of inhibin B (88 (20-195) pg/ml vs 78 (35-182) pg/ml; not significant), LH (0.08 (<0.05-0.99) IU/l vs 0.06 (<0.05-1.61) IU/l; not significant) and FSH (0.60 (0.08-3.73) IU/l vs 0.85 (0.25-2.55); not significant) compared with 156 healthy prepubertal boys, and there were no differences in hormonal levels between boys with uni- or bilateral cryptorchidism. There was no correlation between baseline levels of inhibin B and FSH. In boys younger than 9 years, we found no correlation between baseline levels of inhibin B and LH whereas, in boys older than 9 years, baseline levels of inhibin B were positively correlated to baseline LH (Spearman rank correlation coefficient ((R(s))=0.58, P=0.03). Treatment with hCG (1500 IU intramuscularly twice weekly for 3 weeks) resulted in descensus of testes in 9 out of 18 patients. In all boys but one, irrespective of age, hCG induced a marked increase in testosterone into the adult range (from undetectable to 21.8 (7.0-35.4) nmol/l; P<0.001) and completely suppressed FSH and LH levels. Serum levels of inhibin B increased significantly from 116 (50-195) pg/ml to 147 (94-248) pg/ml (P<0.05), but not uniformly. The increase in serum levels of inhibin B was inversely correlated to baseline inhibin B (Rs=-0.52, P=0.03) and baseline FSH (R(s)=-0.59, P<0.01). CONCLUSIONS: We therefore suggest that, in the prepubertal testes, inhibin B is secreted from the prepubertal Sertoli cells following hCG, whereas early pubertal testes with more differentiated Sertoli cells are not able to secrete inhibin B in response to hCG stimulation, perhaps due to lack of germ cell-derived betaB-subunits. We found (a) normal inhibin B levels in prepubertal boys with uni- or bilateral cryptorchidism, (b) that hCG stimulated testosterone markedly and suppressed FSH and LH levels and (c) that hCG treatment stimulated inhibin B levels in the youngest cryptorchid boys. In the oldest prepubertal boys no hCG-induced changes in inhibin B were shown.

Dietary arginine uptake by the splanchnic region in adult humans

1993 ◽  
Vol 265 (4) ◽  
pp. E532-E539 ◽  
Author(s):  
L. Castillo ◽  
T. E. Chapman ◽  
Y. M. Yu ◽  
A. Ajami ◽  
J. F. Burke ◽  
...  
Keyword(s):  
Young Adult ◽  
Intravenous Infusion ◽  
Route Of Administration ◽  
Healthy Young Adult ◽  
Fed State ◽  
Routes Of Administration ◽  
Adult Men ◽  
Adult Humans ◽  
Plasma Arginine ◽  
Infusion Protocol

To determine the uptake of dietary arginine and leucine by the splanchnic region, two experiments were carried out, each involving four healthy young adult men who received a diet supplying 1 g protein.kg-1.day-1 for 7 and 10 days before conducting a primed constant tracer infusion protocol. In study 1, subjects received for 8 h (3-h fast; 5-h fed state, achieved by a constant intragastric infusion of the diet formula) L-[5,5-2H2; guanidino-15N2]arginine ([M4]Arg), L-[guanidino-13C]arginine ([13C]Arg), and L-[5,5,5-2H3]leucine ([2H3]Leu) simultaneously by an intragastric infusion on day 7 and a repeat of this protocol on day 10 except with tracer administration given by vein. Plasma arginine fluxes were essentially the same for the two arginine tracers but differed significantly with route of administration. In study 2 the subjects received on day 7 a constant intravenous infusion of [13C]Arg and [2H3]Leu and a simultaneous intragastric infusion of [M4]Arg and [1-13C]leucine. On day 10 the routes of administration of these tracer pairs were reversed. During the fed state in study 1, splanchnic uptake of dietary arginine was 31 +/- 10 and 34 +/- 8%, based on the [13C]Arg and [M4]Arg tracers, respectively, and it was significantly higher (P < 0.01) than for leucine, which was 10 +/- 6%. In study 2, splanchnic uptake of dietary arginine, estimated from a series of tracer-protocol combinations for the fed state, was approximately 38% compared with a lower (P < 0.01) value of approximately 15% for leucine.

A case for banking sperm due to increased age: decline in sperm count and motility in young adult men

2015 ◽  
Vol 104 (3) ◽  
pp. e78-e79
Author(s):  
G.M. Centola ◽  
A. Blanchard ◽  
J.L. Demick ◽  
S. Li ◽  
M.L. Eisenberg
Keyword(s):  
Young Adult ◽  
Sperm Count ◽  
Adult Men

scholarly journals Effects of Whisky on Plasma Gastrin and Cholecystokinin in Young Adult Men

2003 ◽  
Vol 31 (3) ◽  
pp. 210-214 ◽  
Author(s):  
T Manabe ◽  
H Sawai ◽  
Y Okada ◽  
H Funahashi ◽  
M Yamamoto ◽  
...  
Keyword(s):  
Young Adult ◽  
Early Phase ◽  
Alcohol Intake ◽  
Serum Amylase ◽  
Plasma Concentrations ◽  
Plasma Gastrin ◽  
Healthy Young Adult ◽  
Gradual Decline ◽  
Adult Men ◽  
Over Time

Whisky (1 g/kg, 21.5% alcohol) was administered orally to healthy young adult male volunteers, and changes in the plasma concentrations of alcohol, acetaldehyde, gastrin, cholecystokinin (CCK) and serum amylase were measured over time. Values for alcohol and acetaldehyde rapidly reached a peak at 30–45 min after alcohol intake, followed by a gradual decline. The plasma gastrin concentration showed a rapid elevation, while the plasma CCK concentration did not exhibit any significant changes in the early phase after alcohol intake. Elevation of CCK was observed after 75 min, however. These results show that intake of whisky stimulates the secretion of gastrin and is associated with a later increase in CCK.

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