scholarly journals Teratogenic Nephrotoxicity induced by aluminium

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Mammona Nasim
Keyword(s):  
Trace Elements ◽  
Environmental Chemicals ◽  
Biological Processes ◽  
Pharmaceutical Drugs ◽  
Mammalian Development ◽  
Chemical Agents ◽  
Uterine Growth ◽  
Intra Uterine Growth Retardation ◽  
Early Mammalian Development

The intensified growth of the modern industry has been accompanied by an increased utilization of metals in the processing of manufactured goods, foods and drugs. The mobilization of many trace elements has resulted in a growing concern about the effects of these substances on various biological processes especially about their possible effects on early mammalian development Hardness of drinking water has positively been correlated to lethal congenital malformations. Chemical agents and pharmaceutical drugs play a very important role in the teratogenesis. Amongst other trace elements or environmental chemicals, aluminium has been reported to have teratogenic properties in chick and rats. So the present study was carried out to establish the role of aluminium containing compounds in producing intra-uterine growth retardation and defected renal development, when the pregnant mothers use these compounds for various periods during pregnancy.

scholarly journals Common principles of early mammalian embryo self-organisation

Development ◽  
2020 ◽  
Vol 147 (14) ◽  
pp. dev183079 ◽  
Author(s):  
Berenika Płusa ◽  
Anna Piliszek
Keyword(s):  
Mammalian Development ◽  
Cellular Mechanisms ◽  
Mammalian Embryo ◽  
Early Mammalian Embryo ◽  
Physical Forces ◽  
Self Organisation ◽  
Unifying Principles ◽  
Morphogenic Process ◽  
Early Mammalian Development

ABSTRACTPre-implantation mammalian development unites extreme plasticity with a robust outcome: the formation of a blastocyst, an organised multi-layered structure ready for implantation. The process of blastocyst formation is one of the best-known examples of self-organisation. The first three cell lineages in mammalian development specify and arrange themselves during the morphogenic process based on cell-cell interactions. Despite decades of research, the unifying principles driving early mammalian development are still not fully defined. Here, we discuss the role of physical forces, and molecular and cellular mechanisms, in driving self-organisation and lineage formation that are shared between eutherian mammals.

Vaso-active factors in pregnancy

1992 ◽  
Vol 4 (1) ◽  
pp. 15-36 ◽  
Author(s):  
L Myatt
Keyword(s):  
Growth Retardation ◽  
Vascular System ◽  
The Body ◽  
Vascular Events ◽  
Uterine Growth ◽  
Vascular Beds ◽  
Intra Uterine Growth Retardation ◽  
Cardio Vascular ◽  
In Pregnancy

Pregnancy results in profound physiological changes in the cardiovascular system, yet these changes are completely reversible. It is apparent that vaso-active factors, some as yet probably unidentified, which act as humoral or local autocrine or paracrine regulators of vasular resistance, play a major role in these cardio-vascular changes. This role may be heightened in pregnancy when there has to be a large increase in blood flow to the uterus and placenta while maintaining adequate flow to other vascular beds. Our knowledge of the mechanisms of action of these vaso-active factors and their interactions with each other still remains incomplete. Alterations in synthesis and action of these vaso-active factors may occur in pregnancies associated with pregnancy-induced hypertension, pre-eclampsia or intra-uterine growth retardation. Investigation of such alterations may help to elucidate the roles of vaso-active factors in both normal and pathological situations. The gestational hormones oestrogen and progesterone, are obviously prime candidates as overall regulators of the cardiovascular changes of pregnancy and as agents which alter the synthesis or action of other vaso-active factors. Currently, much attention is being focused on the role of local autocrine or paracrine vaso-active factors which may be produced by the endothelium or by the underlying vascular smooth muscle cells and alterations in their production or action in the hyptertensive disorders of pregnancy. The endothelium forms the largest endocrine organ within the body and so its importance in the mediation of vascular events should not be under-estimated. The principal objective of this review is to examine the roles of these many autocrine and paracrine vaso-active factors during pregnancy and their relation with the overall regulation of the vascular system. Changes which may occur and be involved in the aetiology of pre-eclampsia and growth retardation will also be examined.

Role of colour doppler in predicting adverse foetal outcomes in pre-eclampsia & intra-uterine growth retardation (IUGR)

2012 ◽  
Vol 2 (7) ◽  
pp. 343-344
Author(s):  
Dr. Purvi B Shah ◽  
◽  
Dr. Mili V Dodia ◽  
Dr. Aparna V Dodia ◽  
Dr. Apoorva V. Dodia
Keyword(s):  
Growth Retardation ◽  
Colour Doppler ◽  
Uterine Growth ◽  
Intra Uterine Growth Retardation

scholarly journals The role of material in homogeneities in biological growth

2005 ◽  
Vol 32 (1) ◽  
pp. 21-38 ◽  
Author(s):  
A. Grillo ◽  
G. Zingali ◽  
S. Federico ◽  
W. Herzog ◽  
G. Giaquinta
Keyword(s):  
Condensed Matter ◽  
Biological Processes ◽  
Living Tissue ◽  
Volumetric Growth ◽  
Biological Growth ◽  
Chemical Agents ◽  
Physical Insight ◽  
Insight Into ◽  
The Continuum

We investigate the influence of the material in homogeneities that are generated by an isotropic growth on the source of mass acting within a growing living tissue. In order to do that, we need to study the interaction between these material in homogeneities and the chemical agents dissolved within the tissue. For this purpose, we use some ideas and methods from Condensed Matter Physics (e.g., the Path Integral technique employed in modeling Brownian processes) and apply them to the Continuum Mechanics description of volumetric Growth. We believe that this approach may provide new physical insight into the interactions between the macroscopic dynamics of living systems and the evolution of the subsystems which activate biological processes.

Role of Colour Doppler in Intra Uterine Growth Retardation and Its Management

2018 ◽  
Vol 6 (2) ◽  
pp. 171-176
Author(s):  
N.I. Anand ◽  
◽  
P.S. Punatar ◽  
Henil Mathukiya ◽  
◽  
...  
Keyword(s):  
Growth Retardation ◽  
Colour Doppler ◽  
Uterine Growth ◽  
Intra Uterine Growth Retardation
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