Paediatric zidovudine dosage recommendation questioned

1994 ◽  
Vol &NA; (926) ◽  
pp. 5
Author(s):  
&NA;
Keyword(s):  
Dosage Recommendation

Potentially Toxic Theophylline Dose Recommendations

PEDIATRICS ◽  
1978 ◽  
Vol 62 (2) ◽  
pp. 275-276
Author(s):  
Leslie Hendeles ◽  
Richard Wyatt ◽  
Miles Weinberger
Keyword(s):  
Therapeutic Range ◽  
Peak Serum ◽  
Serum Concentrations ◽  
Dosage Recommendation ◽  
The 1950S ◽  
Dose Recommendations

We are alarmed by the theophylline dosage recommendation published in a recent Quibron advertisement in Pediatrics (61:A8-A9, April 1978) and labeled as "New Pediatric Dosage" on the outside of sample packages of Quibron Elixir that are mailed to pediatricians. These recommendations, in some cases, approach the excessive doses that produced seizures and death in children during the 1950s.1 Some patients who are rapid metabolizers may require the larger doses recommended in the Quibron advertisement in order to achieve peak serum concentrations in the therapeutic range of 10 to 20 µg/ml.

scholarly journals P39 Establishment of the swiss database for dosing medicinal products in pediatrics

2019 ◽  
Vol 104 (6) ◽  
pp. e33.1-e33
Author(s):  
E Giger ◽  
A Glauser ◽  
D Panis ◽  
R Tilen ◽  
C Berger
Keyword(s):  
Public Health ◽  
Interprofessional Collaboration ◽  
National Database ◽  
Health Administration ◽  
Medicinal Products ◽  
Public Database ◽  
Dosage Recommendation ◽  
Public Health Administration ◽  
Hospital Pharmacists ◽  
Frequency Of Use

BackgroundDrug therapy in children is challenging. Due to the lack of licensed drugs for paediatric use, off-label or unlicensed prescription is frequent. To improve quality and safety of prescription of medicinal products for children in Switzerland, the requirement to create and continuously run a national database was added in the revision of the therapeutic products act (TPA Art. 67a). The task of operating the database was given to SwissPedDose, an association representing eight Swiss children’s hospitals, the Swiss Society of Paediatrics (SGP) and the Swiss Association of Public Health Administration and Hospital Pharmacists (GSASA).MethodsSubstances used in three therapeutic areas ‘general paediatrics’, ‘infectious diseases’ and ‘neonatology’ are selected according to their frequency of use in the eight participating hospitals. Dosage data of substance-indication pairs are requested from the hospital pharmacists. Based on these data and literature review a dosage suggestion consisting of substance, indication, route of administration, dose, daily repetitions and, if applicable, additional remarks is then elaborated by a specialised pharmacist of SwissPedDose. This suggestion is then discussed by experienced physicians delegated from the eight clinics. The elaboration, discussion and agreement on a national dosage recommendation takes place and is documented in an online platform specially programmed for this structured harmonisation process. Once an agreement has been achieved, the national dosage recommendation is sent to the eight participating clinics and published in a free accessible public database.ResultsAs of December 31st 2018, 195 dosage recommendations for children including 87 indications and 54 substances have been harmonised and published and are available for medical professionals on https://swisspeddose.ch/database.ConclusionThe goal of published recommendations for 100 substances by March 2021 is feasible to reach due to interprofessional collaboration. SwissPedDose may thus contribute to a more efficient and safe use of drugs prescribed to children in Switzerland.Disclosure(s)Source of Funding: Project funded by the Federal Office of Public Health. Conflict of interest: None, for all listed authors.

Tobramycin dosage recommendation in patients with cystic fibrosis

Infection ◽  
1989 ◽  
Vol 17 (1) ◽  
pp. 41-41
Author(s):  
R. L. Davis ◽  
P. Mendelman ◽  
Bonnie Ramsey ◽  
A. L. Smith
Keyword(s):  
Cystic Fibrosis ◽  
Dosage Recommendation

Comparison of two misoprostol regimens for mid-trimester pregnancy terminations after FIGO’s misoprostol dosage recommendation in 2012

2015 ◽  
Vol 29 (8) ◽  
pp. 1314-1317 ◽  
Author(s):  
Cihan Cetin ◽  
Selim Buyukkurt ◽  
Gulsah Seydaoglu ◽  
Bekir Kahveci ◽  
Cenk Soysal ◽  
...  
Keyword(s):  
Dosage Recommendation ◽  
Trimester Pregnancy

Mobile Medical Applications for Dosage Recommendation, Drug Adverse Reaction, and Drug Interaction: Review and Comparison

2017 ◽  
Vol 51 (4) ◽  
pp. 480-485 ◽  
Author(s):  
Nur Amirah Apidi ◽  
Muthu Kumar Murugiah ◽  
Rajendran Muthuveloo ◽  
Yee Chang Soh ◽  
Vanni Caruso ◽  
...  
Keyword(s):  
Adverse Reaction ◽  
Drug Interaction ◽  
Medical Applications ◽  
Dosage Recommendation ◽  
Drug Adverse Reaction

scholarly journals Obstetrical Management of an Extremely Overweight Pregnant Woman (184 kg bw) with Special Attention on Thromboprophylaxis

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Boldizsar Horváth ◽  
Judit Skrapits ◽  
József Bódis
Keyword(s):  
Clinical Practice ◽  
Pregnant Woman ◽  
Elective Caesarean Section ◽  
Dose Titration ◽  
Dosage Recommendation ◽  
Upper Arm ◽  
Lower Range ◽  
Obstetrical Management ◽  
Heparin Monitoring ◽  
Heparin Dosage

The 27-year-old pregnant woman has been overweight since her childhood. Endocrinological assessments did not confirm hormonal disease. Her pregnancy was without complication. A signs of intrauterine distress were observed and elective caesarean section was performed under heparin protection because of anatomy unsuitable for delivery per vias naturals. The mother’s bodyweight was 184 kg. By monitoring the change in fX activity LMWH treatment (Enoxaparin) initiated with a dose of 120 mg twice daily and then the dose was gradually elevated to 200 mg twice daily thereby achieving the lower range of the desired therapeutic effect. Apart from mild disorder of wound healing, the recovery was free of complication. The patient suffered from thrombophilia (extremely overweight, pregnant, thrombophlebitis under the knee, surgery, and postoperative immobilization). In case of quite extreme bodyweight there is no dosage recommendation or clinical practice for LMWH. Because of the extreme overweight and the therapeutic dose titration test of heparin, monitoring of fX activity by measurement of inhibition, dosage of heparin other than the recommended (abdominal wall instead of upper arm SC), and the very fluctuating heparin dosage which is well correlating with clinical practice, it is reasonably expected that this case will take interest.

scholarly journals Predictors of Service Dosage, Recommendation, and Usage in an Early Childhood System of Care

2018 ◽  
Vol 28 (2) ◽  
pp. 599-608
Author(s):  
Alayna Schreier ◽  
Robey B. Champine ◽  
Joy S. Kaufman
Keyword(s):  
Early Childhood ◽  
System Of Care ◽  
Dosage Recommendation

scholarly journals PENGARUH KOMBINASI NUTRISI ANORGANIK DAN PUPUK HAYATI TERHADAP POPULASI Azotobacter sp, KANDUNGAN KLOROFIL, SERAPAN N, DAN HASIL TANAMAN TOMAT PADA SISTEM HIDROPONIK

Agrin ◽  
2019 ◽  
Vol 22 (1) ◽  
pp. 66
Author(s):  
Nandha Afrilandha ◽  
Mieke Rochimi Setiawati
Keyword(s):  
Chlorophyll Content ◽  
Block Design ◽  
N Uptake ◽  
Fruit Weight ◽  
Inorganic Nutrient ◽  
Treatment Combination ◽  
Dosage Recommendation ◽  
High Demand ◽  
Randomized Block Design ◽  
Nutrients Uptake

Budidaya hidroponik belum efisien untuk digunakan, salah satu penyebabnya adalah tingginya kebutuhannutrisi. Pemanfaatan pupuk hayati diharapkan bias mengefisiensikan penggunaan nutrisi dan meningkatkanproduktivitas tanaman tomat Tujuan penelitian ini untuk mengetahui pengaruh kombinasi nutrisi anorganik danpupuk hayati terhadap populasi Azotobacter sp, serapan N, kandungan klorofil, dan hasil tanaman tomat padasistem hidroponik. Penelitian ini dilakukan pada bulan Agustus – November 2017 di Rumah Kaca KebunPercobaan Ciparanje Universitas Padjadjaran, Jatinangor, Kabupaten Sumedang, Jawa Barat. Metode penelitianini menggunakan rancangan acak kelompok (RAK). Kombinasi perlakuan terdiri atas rekomendasi nutrisianorganik dengan konsentrasi 100%, 75%, dan 50% dan rekomendasi pupuk hayati 100%, 75%, 50%, dan 25%.Variabel yang diamati meliputi populasi Azotobacter sp, kandungan klorofil, serapan N, jumlah buah tomat danbobot buah tomat. Hasil penelitian ini menunjukkan bahwa tidak terdapat pengaruh nyata pemberian nutrisianorganik dan pupuk hayati terhadap populasi Azotobacter sp, kandungan klorofil, serapan N, serta hasil tanamantomat. Pemberian perlakuan 50% nutrisi Anorganik + 100% pupuk hayati dapat meningkatkan bobot buah sebesar40% dibandingkan pemberian 100% nutrisi anorganik.Kata kunci: Azotobacter sp., klorofil, nutrisi anorganik, hydroponik, tomatABSTRACTHydroponic cultivation is not efficient because of its high demand for nutrients. Therefore, the utilizationof inorganic nutrients and biofertilizer is expected to improve the efficiency of nutrients uptake and increase theproductivity. The aim of research was to determine the effect of combination of inorganic nutrient dosage andbiofertilizer on the population of Azotobacter sp, N uptakes, chlorophyll content, and yield of tomatoes plantinhydroponic systems. This experiment was conducted on August - November 2017 at GreenhouseExperimentGarden Ciparanje Padjadjaran University, Jatinangor, Sumedang Regency, West Java. This research methodused Randomized Block Design (RBD). The treatment combination consisted of dosage recommendation ofinorganic nutrition with 100%, 75% and 50% concentrations, and 100%, 75%, 50%, and 25% of biofertilizer. Thevariables observed included the population of Azotobacter sp, chlorophyll content, N uptake, number of tomatoesand weight of tomatoes. The result of this study indicated that the effect of application both, inorganic nutrientsand biofertilizer did not significantly affect the population of Azotobacter sp, chlorophyll content, N uptakes, andyield of tomatoes. The application of 50% Inorganic nutrition + 100% of biofertilizer increased fruit weight by40% compared to 100% of inorganic nutrients.Keywords: Azotobacter sp., chlorophyll, biofertilizer, hydroponic, tomato

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