scholarly journals Assessment of artificial intelligence models for calculating optimum properties of lined channels

2020 ◽  
Vol 22 (5) ◽  
pp. 1410-1423 ◽  
Author(s):  
Majid Niazkar

Abstract Lined channels with trapezoidal, rectangular and triangular sections are the most common manmade canals in practice. Since the construction cost plays a key role in water conveyance projects, it has been considered as the prominent factor in optimum channel designs. In this study, artificial neural networks (ANN) and genetic programming (GP) are used to determine optimum channel geometries for trapezoidal-family cross sections. For this purpose, the problem statement is treated as an optimization problem whose objective function and constraint are earthwork and lining costs and Manning's equation, respectively. The comparison remarkably demonstrates that the applied artificial intelligence (AI) models achieved much closer results to the numerical benchmark solutions than the available explicit equations for optimum design of lined channels with trapezoidal, rectangular and triangular sections. Also, investigating the average of absolute relative errors obtained for determination of dimensionless geometries of trapezoidal-family channels using AI models shows that this criterion will not be more than 0.0013 for the worst case, which indicates the high accuracy of AI models in optimum design of trapezoidal channels.

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Albert T. Young ◽  
Kristen Fernandez ◽  
Jacob Pfau ◽  
Rasika Reddy ◽  
Nhat Anh Cao ◽  
...  

AbstractArtificial intelligence models match or exceed dermatologists in melanoma image classification. Less is known about their robustness against real-world variations, and clinicians may incorrectly assume that a model with an acceptable area under the receiver operating characteristic curve or related performance metric is ready for clinical use. Here, we systematically assessed the performance of dermatologist-level convolutional neural networks (CNNs) on real-world non-curated images by applying computational “stress tests”. Our goal was to create a proxy environment in which to comprehensively test the generalizability of off-the-shelf CNNs developed without training or evaluation protocols specific to individual clinics. We found inconsistent predictions on images captured repeatedly in the same setting or subjected to simple transformations (e.g., rotation). Such transformations resulted in false positive or negative predictions for 6.5–22% of skin lesions across test datasets. Our findings indicate that models meeting conventionally reported metrics need further validation with computational stress tests to assess clinic readiness.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Xinran Wang ◽  
Liang Wang ◽  
Hong Bu ◽  
Ningning Zhang ◽  
Meng Yue ◽  
...  

AbstractProgrammed death ligand-1 (PD-L1) expression is a key biomarker to screen patients for PD-1/PD-L1-targeted immunotherapy. However, a subjective assessment guide on PD-L1 expression of tumor-infiltrating immune cells (IC) scoring is currently adopted in clinical practice with low concordance. Therefore, a repeatable and quantifiable PD-L1 IC scoring method of breast cancer is desirable. In this study, we propose a deep learning-based artificial intelligence-assisted (AI-assisted) model for PD-L1 IC scoring. Three rounds of ring studies (RSs) involving 31 pathologists from 10 hospitals were carried out, using the current guideline in the first two rounds (RS1, RS2) and our AI scoring model in the last round (RS3). A total of 109 PD-L1 (Ventana SP142) immunohistochemistry (IHC) stained images were assessed and the role of the AI-assisted model was evaluated. With the assistance of AI, the scoring concordance across pathologists was boosted to excellent in RS3 (0.950, 95% confidence interval (CI): 0.936–0.962) from moderate in RS1 (0.674, 95% CI: 0.614–0.735) and RS2 (0.736, 95% CI: 0.683–0.789). The 2- and 4-category scoring accuracy were improved by 4.2% (0.959, 95% CI: 0.953–0.964) and 13% (0.815, 95% CI: 0.803–0.827) (p < 0.001). The AI results were generally accepted by pathologists with 61% “fully accepted” and 91% “almost accepted”. The proposed AI-assisted method can help pathologists at all levels to improve the PD-L1 assay (SP-142) IC assessment in breast cancer in terms of both accuracy and concordance. The AI tool provides a scheme to standardize the PD-L1 IC scoring in clinical practice.


Author(s):  
Kasuni E. Adikari ◽  
Sangam Shrestha ◽  
Dhanika T. Ratnayake ◽  
Aakanchya Budhathoki ◽  
Mohana S. Shanmugam ◽  
...  

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