scholarly journals Giant cell reparative ethmoid granuloma: a clinical case with a review of the literature

2021 ◽  
Vol 8 (3) ◽  
pp. 102-108
Author(s):  
A. D. Rodina ◽  
T. V. Gorbunova ◽  
A. S. Krylov ◽  
A. A. Odzharova ◽  
O. A. Merkulov ◽  
...  

Giant cell reparative granuloma (GCRG) is a rare benign tumor that develops in the first two decades of life. Data on the incidence of GCRG in children vary significantly depending on the number of observations and methods of statistical data processing. GCRG is more common in long bones, but rare cases of damage to the bones of the facial skeleton, which account for only 2–12 %, have been described. The etiological factors of GCRG are unknown, but genetic predisposition and intraosseous hemorrhages after an injury are the predisposing factors. Despite its benign nature, the process can be locally aggressive. Rapid invasive growth, complex anatomy of the base of the skull in childhood make surgical treatment in this place quite difficult. The clinical symptoms of ethmoid GCRG are nonspecific and depend on the site involved and the degree of local destruction. Distinctive morphological features of this neoplasm are the presence of multinucleated giant cells, cellular fibrous tissue and hemorrhages. Diagnostics of this disease includes endoscopic examination of the nasal cavity and nasopharynx, magnetic resonance and X-ray computed tomography of the skull base, paranasal sinuses with intravenous contrast, radioisotope research methods. We report a case of the development of GCRG in a 6-year-old child, along with the clinical picture, X-ray, scintigraphic and morphological data. The method of choice for the treatment of GCRG was its complete surgical removal.

2014 ◽  
Vol 13 (3) ◽  
pp. 200-203
Author(s):  
Renatas Aškinis ◽  
Arnoldas Krasauskas ◽  
Sigitas Zaremba ◽  
Saulius Cicėnas

Neurilemoma – periferinių nervų dangalų auglys. Jis auga lėtai ir pradžia dažniausiai būna besimptomė. Pasiekęs kritinį dydį auglys, priklausomai nuo atsiradimo vietos, pasireiškia spaudimo į aplinkinius organus klinika. Neurilemomos dažniausiai atsiranda galūnėse 30–50 gyvenimo metais nepriklausomai nuo lyties. Klajoklio nervo neurilemoma yra nedažna patologija, o krūtininės klajoklio nervo dalies neurilemoma pasitaiko itin retai. Diagnozuojant svarbiausi yra radiologiniai tyrimo metodai. Gydymas – chirurginis auglio pašalinimas. Pateikiame krūtininės klajoklio nervo dalies neurilemomos, nustatytos 39 metų moteriai, klinikinį atvejį. Auglys aptiktas radiologiniais tyrimais (krūtinės rentgeno, kompiuterinės tomografijos ir tarpuplaučio magnetinio branduolių rezonanso), pašalintas naudojant vaizdo torakoskopinę (VATS) metodiką. Diagnozė galutinai patvirtinta histologiniu tyrimu. Aštuntą parą po operacijos ligonė išrašyta į namus.Reikšminiai žodžiai: neurilemoma, klajoklis nervas, operacija Neurilemoma of intrathoracal vagal nerve: clinical caseRenatas Aškinis, Arnoldas Krasauskas, Sigitas Zaremba, Saulius Cicėnas Neurilemoma is a tumour of peripleurical nervous tissues. It grows slowly and has an asymptomatic manifestation. During tumour enlargement, depending on localisation, clinical symptoms appear because of the tumour pressure to the surrounding tissues. Mostly neurilemomas appear in extremities of patients aged 30–50 years. N. vagus neurilemoma is a very rare disease. The diagnosis is made using radiology. The treatment is surgical removal. We present a clinical case of intrathoracal n. vagus neurilemoma in a 39-year-old woman. The diagnosis was made using radiological findings (chest X-ray, chest CT, and the MRI of the mediastinum). The removal of the tumour was made by VATS. The diagnosis was proved morphologically. After 8 days, the patient was discharged from the hospital.Key words: neurilemoma, vagal nerve, operation


Author(s):  
Abdulla Alnakshabandi ◽  
Khaled Hashim Sultan

<p><strong>Background: </strong>Adenoid is a prevalent condition among children. Adenoidectomy has been done based on clinical symptoms. The purpose of this study is to determine the agreement between clinical features of adenoid enlargement, X-ray and adenoid size.</p><p><strong>Methods:</strong> Hundred symptomatic children were enrolled into this study at ENT. Department of Al-Bin Sina teaching hospital in Mosul city of Iraq. History was taken, clinical examination for adenoid enlargement and skull X-ray (lateral view) were performed for all children with assessment of adenoid size 1 day before operation.</p><p><strong>Results: </strong>The respondent composed of 5% male children and 46% females with average age of 6 years. Adenoid facies were the most frequent presentation followed by snoring then nasal obstruction. Around 64% had positive otoscopic findings and another 58% had hearing impairment and only 22% had ear discharge. All of the clinical findings showed (100%) sensitivity and specificity vary from (64%) to (90%). The accuracy rate for clinical   features ranged from 92% to 98%. X-ray findings show a low accuracy rate (92%) in comparison to others.</p><p><strong>Conclusions: </strong>Clinical findings could be used to select children for adenoidectomy, especially when endoscopic examination is not available or cannot be performed.</p><p><strong> </strong></p>


2019 ◽  
Vol 2 (1) ◽  
pp. 01-04
Author(s):  
Nilotpol Kashyap ◽  
Manisha Upadhyay ◽  
Rupam Tripathi ◽  
Pallavi Pawar ◽  
Ranjeet Kumar Prasad Sah ◽  
...  

Central giant cell granuloma (central giant cell granuloma) is an uncommon benign bony lesion that occurs in the mandible and maxilla and accounts for approximately 7% of all benign tumours of the jaws [1]. The World Health Organization (WHO) has defined central giant cell granuloma as an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of haemorrhage, aggregations of multinucleated giant cells and occasional trabeculae of woven bone [2]. Central giant cell granuloma occurs predominantly in children or young adults, with approximately 75%of cases presenting before 30 years of age although presentation can occur at any age [3]. Females are affected more frequently than males, with a ratio of 2:1


2020 ◽  
Vol 3 (2) ◽  
pp. 01-05
Author(s):  
Cinzia Casu

The Central Giant Cell Granuloma is an uncommon lesion, accounting less than 7% of all benign jaw lesions. In 1953, Jaffe was the first to describe these lesions as a giant cell reparative granuloma of the jaw bones, and in 1971, thanks to Pindborg and Kramer, it was included in the current nomenclature. The aetiology of CGCG is unknown, there is also a peripheral type that some authors consider the most common in maxillary bones. WHO defines CGCG as an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells, and some trabeculae of woven bone. The radiographic appearance of CGCGs is not pathognomonic. CGCGs should be differentiated from other lesions of the jaws such as Brown’s tumour of hyperparathyroidism, fibrous dysplasia, aneurysmal bone cysts, giant cell tumours, fibro-osseous lesions, and other malignancies that arise in the jaw bones. Furthermore, it needs to be differentiated even from some genetic syndromes, such as Cherubism, type 1-neurofibromatosis and Noonan’s syndrome. The aim of this study is to focus on radiographic features of CGCG in order to achieve an appropriate tool for diagnosis.


2012 ◽  
Vol 11 (3-4) ◽  
pp. 89-92
Author(s):  
Renatas Aškinis ◽  
Arnoldas Krasauskas ◽  
Sigitas Zaremba ◽  
Saulius Cicėnas

Neurilemoma – periferinių nervų dangalų auglys, kuris auga lėtai ir jo pradžia dažniausiai būna besimptomė. Pasiekę kritinį dydį augliai, priklausomai nuo atsiradimo vietos, pasireiškia spaudimo į aplinkinius organus klinika. Neurilemomos dažniausiai atsiranda galūnėse 30–50-ais gyvenimo metais ir nuo lyties nepriklauso. Klajoklio nervo neurilemoma yra nedažna patologija, o krūtininės klajoklio nervo dalies neurilemoma pasitaiko itin retai. Diagnostikai svarbiausi yra radiologiniai tyrimo metodai. Gydymas – chirurginis auglio šalinimas. Pateikiame krūtininės klajoklio nervo dalies neurilemomos, nustatytos 39 metų moteriai, klinikinį atvejį. Auglys aptiktas radiologiniais tyrimais (krūtinės rentgeniniu, kompiuterinės tomografijos ir tarpuplaučio magnetinio branduolių rezonanso), pašalintas naudojant vaizdo torakoskopinę metodiką. Diagnozė galutinai patvirtinta histologiniu tyrimu. Aštuntą parą po operacijos ligonė išrašyta į namus.Reikšminiai žodžiai: neurilemoma, klajoklis nervas, operacija.Neurilemoma of intrathoracal vagal nerve: case report Neurilemoma is a tumour of peripleurical nervous tissues. It grows slowly and has an asymptomatic manifestation. During tumour enlargement, depending on its localization, clinical symptoms appear due to the tumour pressure to surrounding tissues. Neurilemomas mostly appear in the extremities of patients aged 30–50 years. N. vagus neurilemoma is a very rare disease. The diagnosis is made using radiology. Its treatment is surgical removal. We present a clinical case of intrathoracal nervus vagus neurilemoma in a 39-y woman. The diagnosis was based on radiological findings (chest X-ray, chest CT, and mediastinum MRI). The removal of the tumour was made by the VATS method. The diagnosis was proven morphologically. After 8 days the patient was discharged from the hospital.Key words: neurilemoma, vagal nerve, operation.


2018 ◽  
Vol 7 (3) ◽  
pp. 37
Author(s):  
Nahla Kechiche ◽  
Rabeb Farhani ◽  
Badii Hmida ◽  
Rachida Lamiri ◽  
Aziza Ezzi ◽  
...  

Congenital esophageal web is a rare disorder that presents a diagnostic and management challenge. In a female infant born at 31 weeks of gestation, significant secretions and respiratory distress were noted at birth. Chest X-ray demonstrated the nasogastric tube in the esogastric junction with no distal bowel gas. Esophagogram showed a congenital web near the esogastric junction. An endoscopic examination under general anesthesia showed a complete, thick membrane on the distal esophageal lumen. Endoscopic incision and cauterization of the web through the midline were performed, improving the clinical symptoms and esophageal stenosis.


2014 ◽  
Vol 13 (3) ◽  
pp. 200-203
Author(s):  
Renatas Aškinis ◽  
Arnoldas Krasauskas ◽  
Sigitas Zaremba ◽  
Saulius Cicėnas

Neurilemoma – periferinių nervų dangalų auglys. Jis auga lėtai ir pradžia dažniausiai būna besimptomė. Pasiekęs kritinį dydį auglys, priklausomai nuo atsiradimo vietos, pasireiškia spaudimo į aplinkinius organus klinika. Neurilemomos dažniausiai atsiranda galūnėse 30–50 gyvenimo metais nepriklausomai nuo lyties. Klajoklio nervo neurilemoma yra nedažna patologija, o krūtininės klajoklio nervo dalies neurilemoma pasitaiko itin retai. Diagnozuojant svarbiausi yra radiologiniai tyrimo metodai. Gydymas – chirurginis auglio pašalinimas. Pateikiame krūtininės klajoklio nervo dalies neurilemomos, nustatytos 39 metų moteriai, klinikinį atvejį. Auglys aptiktas radiologiniais tyrimais (krūtinės rentgeno, kompiuterinės tomografijos ir tarpuplaučio magnetinio branduolių rezonanso), pašalintas naudojant vaizdo torakoskopinę (VATS) metodiką. Diagnozė galutinai patvirtinta histologiniu tyrimu. Aštuntą parą po operacijos ligonė išrašyta į namus.Reikšminiai žodžiai: neurilemoma, klajoklis nervas, operacija Neurilemoma of intrathoracal vagal nerve: clinical caseRenatas Aškinis, Arnoldas Krasauskas, Sigitas Zaremba, Saulius Cicėnas Neurilemoma is a tumour of peripleurical nervous tissues. It grows slowly and has an asymptomatic manifestation. During tumour enlargement, depending on localisation, clinical symptoms appear because of the tumour pressure to the surrounding tissues. Mostly neurilemomas appear in extremities of patients aged 30–50 years. N. vagus neurilemoma is a very rare disease. The diagnosis is made using radiology. The treatment is surgical removal. We present a clinical case of intrathoracal n. vagus neurilemoma in a 39-year-old woman. The diagnosis was made using radiological findings (chest X-ray, chest CT, and the MRI of the mediastinum). The removal of the tumour was made by VATS. The diagnosis was proved morphologically. After 8 days, the patient was discharged from the hospital.Key words: neurilemoma, vagal nerve, operation


2021 ◽  
pp. 1-3
Author(s):  
Aicha Ibourk ◽  

Introduction: Central giant cell granuloma (CGCG) is a rare bony lesion in the Head and Neck region. It is a non-odontogenic tumor never seen in any other bone of the skeleton. It is an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells and occasionally trabeculae of woven bone. Case Report: We report a case of a 50-year-old female patient with swelling on the right side of face for 4 months. Intraoral examination shows a mass in right lower jaw in the region of 45 and 46 edentulous areas. The swelling had smooth surface, firm and tender on palpation. There was no expansion of lingual region. The radiological examination revealed a well-defined multiloculated expansile and lytic lesion in the right mandible, extending from the 44 to 47 with a resorption of teeth 44. The patient underwent incisional biopsy and the diagnosis of CGCG and brown tumor of hyperparathyroidism was proposed. According to the clinical radiological and biological findings, the diagnosis of CGCG was confirmed. The enucleation of the lesion with the extraction of 44 was done. Discussion: Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the head and neck with potential for aggressive and locally destructive behaviour. Lesions of the maxilla tend to expand more than those of the mandible due to the thinner cortices and spongy tissue of this location. Surgical removal is the most common treatment; however, it may be disfiguring in aggressive cases, especially for lesions located in the maxilla. Alternative treatments, such as intralesional corticosteroid injections, have been performed with satisfactory results.


2015 ◽  
Vol 5 (3) ◽  
pp. 178-180 ◽  
Author(s):  
Harishchandra Rai ◽  
M Shaila ◽  
Gourav Ghosh ◽  
PD Suhasini

ABSTRACT Granuloma formation is a specific type of chronic inflammation initiated by infectious and noninfectious agents with an aggregation of multinucleated giant cells. Foreign body giant cells (FBGCs) most commonly observed at the tissue/material interface where the size of foreign particulate is too large to permit macrophage phagocytosis. In this context, adherent macrophages and FBGCs constitute the foreign body reaction. Foreign-body giant cell granulomas have been reported to cause clinical symptoms from months to decades after a surgical procedure and can present with a variety of symptoms, usually on the basis of location. Foreign-body giant cell granulomas in the mandible are rare lesions, here we report a case of FBGC granuloma in the mandible that developed after endodontic treatment. How to cite this article Rai H, Shaila M, Ghosh G, Suhasini PD. Foreign Body Giant Cell Granuloma of the Mandible Subsequent to Endodontic Surgery. J Contemp Dent 2015;5(3):178-180.


2019 ◽  
Vol 98 (4) ◽  
pp. 167-173

Introduction: Alveolar echinococcosis (AE) is a zoonosis caused by Echinococcus multilocularis. AE is primarily localised in the liver. Echinococcus multilocularis imitates tumour-like behaviour. It can metastasise through blood or lymphatic system to distant organs. Echinococcosis often remains asymptomatic due to its long incubation period and indistinct symptoms. Clinical symptoms are determined by the parasite’s location. Diagnosis of echinococcosis is based on medical history, clinical symptoms, laboratory tests, serology results, imaging methods and final histology findings. Surgical removal of the cyst with a safety margin, followed by chemotherapy is the therapeutic method of choice. Case report: We present a case report of alveolar echinococcosis in a thirty-year-old female patient in whom we surgically removed multiple liver foci of alveolar echinococcosis. The disease recurred after two years and required another surgical intervention. Conclusions: Alveolar echinococcosis is a disease with a high potential for a complete cure provided that it is diagnosed early and that the recommended therapeutic procedures are strictly adhered to.


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