scholarly journals Pulmonary Hypertension Roundtable: The Role of Exercise in Clinical Practice and Clinical Trials

2019 ◽  
Vol 18 (2) ◽  
pp. 63-67

On May 20, 2019, Guest Editor Ronald Oudiz, MD, Director of the Pulmonary Hypertension Program at Harbor-UCLA Medical Center in Los Angeles, California, led a discussion with Aaron Waxman, MD, PhD, Director of the Center for Pulmonary Heart Disease at Brigham and Women's Hospital and Harvard Medical School in Boston, Massachusetts, and Robert Naeije, MD, Professor Emeritus at the Free University of Brussels, Belgium.

2015 ◽  
Vol 14 (3) ◽  
pp. 161-165

While pulmonary hypertension itself is a rare disorder, its association has been identified in conjunction with other rare disorders, which is the theme of this issue of Advances in Pulmonary Hypertension. Co-guest editor Sonja Bartolome, MD, facilitated a discussion regarding the experiences and perceptions of leading PH experts—many authors in this issue—on this topic. Participating were co-guest editor Kelly Chin, MD, University of Texas Southwestern Medical Center; Murali Chakinala, MD, Washington University School of Medicine; Richard Channick, MD, Harvard Medical School; Jean Elwing, MD, University of Cincinnati Medical Center; and adding to the comments later, Robert Baughman, MD, University of Cincinnati. Their conversation follows.


2015 ◽  
Vol 14 (2) ◽  
pp. 105-110

Guest editor Teresa De Marco, MD, along with Brian Shapiro, MD, Mayo Clinic, Jacksonville, FL, convened a panel of experts to discuss the challenges in diagnosis and treatment and the emerging science regarding pulmonary hypertension due to left heart disease. Contributing to the engaging discussion were James Fang, MD, University of Utah School of Medicine; Barry Borlaug, MD, Mayo Clinic, Rochester, MN; and Srinivas Murali, MD, Allegheny Health Network, Pittsburgh, PA.


PEDIATRICS ◽  
1958 ◽  
Vol 21 (1) ◽  
pp. 165-165
Author(s):  
PAUL R. LURIE

Many books on rheumatic fever, congenital heart disease, laboratory diagnosis of heart diseases, and lengthy sections on cardiologic subjects in pediatric textbooks have been written but until now there is no comprehensive textbook in the field of pediatric cardiology. It is fortunate that the first book to appear to fill this real need is an excellent one. Dr. Nadas, of the Children's Medical Center in Boston and Harvard Medical School, is a recognized authority in the field of cardiology and has contributed much to its recent rapid development.


Author(s):  
Sergio Caravita ◽  
Andrea Faini ◽  
Antoine Bondue ◽  
Robert Naeije ◽  
Gianfranco Parati ◽  
...  

2015 ◽  
Vol 24 (138) ◽  
pp. 642-652 ◽  
Author(s):  
Stephan Rosenkranz ◽  
Ioana R. Preston

Right heart catheterisation (RHC) plays a central role in identifying pulmonary hypertension (PH) disorders, and is required to definitively diagnose pulmonary arterial hypertension (PAH). Despite widespread acceptance, there is a lack of guidance regarding the best practice for performing RHC in clinical practice. In order to ensure the correct evaluation of haemodynamic parameters directly measured or calculated from RHC, attention should be drawn to standardising procedures such as the position of the pressure transducer and catheter balloon inflation volume. Measurement of pulmonary arterial wedge pressure, in particular, is vulnerable to over- or under-wedging, which can give rise to false readings. In turn, errors in RHC measurement and data interpretation can complicate the differentiation of PAH from other PH disorders and lead to misdiagnosis. In addition to diagnosis, the role of RHC in conjunction with noninvasive tests is widening rapidly to encompass monitoring of treatment response and establishing prognosis of patients diagnosed with PAH. However, further standardisation of RHC is warranted to ensure optimal use in routine clinical practice.


1979 ◽  
Author(s):  
J.R.A. Mitchell

The disappointing performance of anticoagulants in the prophylaxis of coronary heart disease led to the realisation that components other than fibrin play a major part in the structure of arterial thrombi. Attention has therefore been focussed on the possible role of agents which modify platelet behaviour. Novel agents which alter thromboxane synthesis will not be available for large-scale clinical trials for some years, so the present trials are assessing the value of platelet-modifying agents which are already in use for other purposes. The implications of the Antura-Reinfarction study and the role of aspirin and persantin will be discussed.Attention will also be drawn to the importance of using valid end-points to assess potential anti-thrombotic regimes in coronary disease. The differential implications of using infarction, sudden death, pump failure, dysrhythmias and re-infarction as end-points in trials will be described.


2010 ◽  
Vol 126 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Paul Jurasz ◽  
David Courtman ◽  
Saeid Babaie ◽  
Duncan J. Stewart

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