Cm38: A New Antimicrobial Peptide Active Against Klebsiella pneumoniae is Homologous to Cn11

2015 ◽  
Vol 22 (2) ◽  
pp. 164-172 ◽  
Author(s):  
Duenas-Cuellar, R.A. ◽  
Kushmerick, C. ◽  
Naves, L.A. ◽  
Batista, I.F.C. ◽  
Guerrero-Vargas, J.A. ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Antimicrobial Peptide

scholarly journals “Clicking” an Ionic Liquid to a Potent Antimicrobial Peptide: On the Route towards Improved Stability

2020 ◽  
Vol 21 (17) ◽  
pp. 6174
Author(s):  
Ana Gomes ◽  
Lucinda J. Bessa ◽  
Patrícia Correia ◽  
Iva Fernandes ◽  
Ricardo Ferraz ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Klebsiella Pneumoniae ◽  
Antimicrobial Peptide ◽  
Clinical Isolate ◽  
Bioactive Peptides ◽  
Multidrug Resistant ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Improved Stability

A covalent conjugate between an antibacterial ionic liquid and an antimicrobial peptide was produced via “click” chemistry, and found to retain the parent peptide’s activity against multidrug-resistant clinical isolates of Gram-negative bacteria, and antibiofilm action on a resistant clinical isolate of Klebsiella pneumoniae, while exhibiting much improved stability towards tyrosinase-mediated modifications. This unprecedented communication is a prelude for the promise held by ionic liquids -based approaches as tools to improve the action of bioactive peptides.

Application of S-thanatin, an antimicrobial peptide derived from thanatin, in mouse model of Klebsiella pneumoniae infection

Peptides ◽  
2013 ◽  
Vol 45 ◽  
pp. 73-77 ◽  
Author(s):  
Guoqiu Wu ◽  
Pengpeng Wu ◽  
Xiulei Xue ◽  
Xuejiao Yan ◽  
Siru Liu ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Mouse Model ◽  
Antimicrobial Peptide

scholarly journals Exogenous fatty acids alter phospholipid composition, membrane permeability, capacity for biofilm formation, and antimicrobial peptide susceptibility in Klebsiella pneumoniae

2018 ◽  
Vol 8 (2) ◽  
pp. e00635 ◽  
Author(s):  
Chelsea R. Hobby ◽  
Joshua L. Herndon ◽  
Colton A. Morrow ◽  
Rachel E. Peters ◽  
Steven J. K. Symes ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Klebsiella Pneumoniae ◽  
Antimicrobial Peptide ◽  
Membrane Permeability ◽  
Biofilm Formation ◽  
Phospholipid Composition

scholarly journals Effects of the Antimicrobial Peptide LL-37 and Innate Effector Mechanisms in Colistin-Resistant Klebsiella pneumoniae With mgrB Insertions

2019 ◽  
Vol 10 ◽  
Author(s):  
Hissa M. Al-Farsi ◽  
Salma Al-Adwani ◽  
Sultan Ahmed ◽  
Carmen Vogt ◽  
Anoop T. Ambikan ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Antimicrobial Peptide ◽  
Innate Effector ◽  
Effector Mechanisms
Sign in / Sign up

Export Citation Format

Share Document