The Dual Role of Nitric Oxide in Glioma

2010 ◽  
Vol 16 (4) ◽  
pp. 428-430 ◽  
Author(s):  
Wiaam Badn ◽  
Peter Siesjo
Keyword(s):  
Nitric Oxide ◽  
Dual Role

Dual Role of Nitric Oxide in the Pathogenesis of Parkinson's Disease

2014 ◽  
Vol 1 (4) ◽  
pp. 243-253 ◽  
Author(s):  
Vaibhav Walia ◽  
Anuradha Sharma ◽  
Monika Gahlawat ◽  
O. P. Dube
Keyword(s):  
Nitric Oxide ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Dual Role

Dual Role of Nitric Oxide in Cancer Biology

2010 ◽  
pp. 39-57 ◽  
Author(s):  
Shehla Pervin ◽  
Rajan Singh ◽  
Suvajit Sen ◽  
Gautam Chaudhuri
Keyword(s):  
Nitric Oxide ◽  
Cancer Biology ◽  
Dual Role

Dual role of inducible nitric oxide synthase in acute asbestos-induced lung injury

2002 ◽  
Vol 33 (4) ◽  
pp. 491-501 ◽  
Author(s):  
Martina Dörger ◽  
Anne-Marie Allmeling ◽  
Rainer Kiefmann ◽  
Alke Schropp ◽  
Fritz Krombach
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Lung Injury ◽  
Inducible Nitric Oxide Synthase ◽  
Dual Role ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

scholarly journals Dual Role of Nitric Oxide in Pancreatic β-Cells

2013 ◽  
Vol 123 (4) ◽  
pp. 295-300 ◽  
Author(s):  
Yukiko Kurohane Kaneko ◽  
Tomohisa Ishikawa
Keyword(s):  
Nitric Oxide ◽  
Dual Role ◽  
Β Cells ◽  
Pancreatic Β Cells

scholarly journals The Dual Role of Inducible Nitric Oxide Synthase in Myocardial Ischemia/Reperfusion Injury: Friend or Foe?

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Xin Yu ◽  
Liang Ge ◽  
Liang Niu ◽  
Xin Lian ◽  
Haichun Ma ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Myocardial Ischemia ◽  
Reperfusion Injury ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Dual Role ◽  
No Signaling ◽  
Myocardial Ischemia Reperfusion Injury ◽  
Myocardial Ischemia Reperfusion

Nitric oxide synthases (NOSs) are a family of enzymes that are responsible for the synthesis of nitric oxide (NO) from the amino acid L-arginine in the body. Among the three key NOSs, the expression of inducible NOS (iNOS) can only be induced by inflammatory stimuli and contribute to the large amount of NO production. iNOS-derived NO plays an important role in various physiological and pathophysiological conditions, including the ischemic heart disease. Nowadays, the development of specific iNOS inhibitors and the availability of iNOS knockout mice have provided substantial evidence to support the role of iNOS/NO signaling in the myocardium. Nevertheless, the role of iNOS/NO signaling in the myocardial ischemic reperfusion injury is very complex and highly perplexing; both detrimental and beneficial effects of iNOS have been described. Thus, this review will aim at providing basic insights into the current progress of the role of iNOS in myocardial ischemia reperfusion injury. A better understanding of the dual role of iNOS in details may help facilitate the development of more effective therapies for the management of ischemic heart diseases.

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