This in vitro study focuses on the green synthesis of selenium nanoparticles using Capparis decidua and its anti-inflammatory activity. Nanotechnology is the speciality associated with Material science and biology, rather than a particular field. It involves the formulation of particles at nanoscale known as Nanoparticles, where they have control over bulk macroscopic properties of the same material. Selenium, being a 'Drug nanocarrier', possesses strong antibacterial, antioxidant and anti-cancer as well as anti-inflammatory properties. As the medicinal plant Capparis decidua possesses a lot of phytochemicals, this study combined it to synthesise selenium nanoparticles, and anti-inflammatory properties were analysed. Synthesis of Selenium nanoparticles using Capparis decidua extract, collection of NPs using centrifugation, analysis of anti-inflammatory using UV spectroscopy and inhibition of Bovine serum albumin denaturation assay were performed. Biosynthesised selenium nanoparticles using Capparis decidua exhibit effective anti-inflammatory properties and act as an alternative candidate for steroidal and non-steroidal anti-inflammatory drugs. On account of performing the Green synthesis of selenium nanoparticles along with the combination of Capparis decidua, it is evident that Capparis decidua possesses effective anti-inflammatory with increasing concentrations up to 5muL. In future, we can encounter further efficacy by raising the concentrations by adding new formulations other than Capparis decidua
Potential role of acetylsalicilic acid and other non-steroidal anti-inflammatory drugs in cancer risk reduction (literature review)