Baicalein-Phospholipid Complex: A Novel Drug Delivery Technology for Phytotherapeutics

2013 ◽  
Vol 10 (3) ◽  
pp. 224-232 ◽  
Author(s):  
Devendra Singh Rawat ◽  
Bandana K. Thakur ◽  
Mona Semalty ◽  
Ajay Semalty ◽  
Prabhakar Badoni ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Phospholipid Complex ◽  
Novel Drug ◽  
Delivery Technology

scholarly journals Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Pritam Dinesh Choudhary ◽  
Harshal Ashok Pawar
Keyword(s):  
Drug Delivery ◽  
Drug Absorption ◽  
Drug Delivery Systems ◽  
Chemical Constituents ◽  
Dosage Forms ◽  
Polymeric Compounds ◽  
Recent Trends ◽  
Natural Drugs ◽  
Novel Drug ◽  
Delivery Technology

Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfil specific functions and in some cases they directly or indirectly influence the extent and/or rate of drug release and drug absorption. Recent trends towards use of plant based and natural products demand the replacement of synthetic additives with natural ones. Today, the whole world is increasingly interested in natural drugs and excipients. These natural materials have many advantages over synthetic ones as they are chemically inert, nontoxic, less expensive, biodegradable, and widely available. This review discusses majority of the plant-derived polymeric compounds (gums and mucilage’s), their sources, chemical constituents, uses, and some recent investigations as excipients in novel drug delivery systems.

Recent expansions in an emergent novel drug delivery technology: Emulgel

2013 ◽  
Vol 171 (2) ◽  
pp. 122-132 ◽  
Author(s):  
Ajazuddin ◽  
Amit Alexander ◽  
Ajita Khichariya ◽  
Saurabh Gupta ◽  
Ravish J. Patel ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Novel Drug ◽  
Delivery Technology

scholarly journals The L utonix ® drug-coated balloon: A novel drug delivery technology for the treatment of vascular disease

2017 ◽  
Vol 112 ◽  
pp. 78-87 ◽  
Author(s):  
Ian Schorn ◽  
Harrison Malinoff ◽  
Steven Anderson ◽  
Cyal Lecy ◽  
Jeffrey Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Vascular Disease ◽  
Novel Drug ◽  
Drug Coated Balloon ◽  
Delivery Technology

Status of novel drug delivery technology for phytotherapeutics

2009 ◽  
Vol 6 (6) ◽  
pp. 625-637 ◽  
Author(s):  
S Mohamed Musthaba ◽  
Sanjula Baboota ◽  
Sayeed Ahmed ◽  
Alka Ahuja ◽  
Javed Ali
Keyword(s):  
Drug Delivery ◽  
Novel Drug ◽  
Delivery Technology

scholarly journals Functionality and Acceptance of the EsoCap System—A Novel Film-Based Drug Delivery Technology: Results of an In Vivo Study

Pharmaceutics ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 828
Author(s):  
Christoph Rosenbaum ◽  
Michael Grimm ◽  
Julius Krause ◽  
Adrian Rump ◽  
Rebecca Kessler ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Polymer Film ◽  
Esophageal Mucosa ◽  
Esophageal Diseases ◽  
System A ◽  
Mri Scans ◽  
Novel Drug ◽  
First Time ◽  
Delivery Technology

There are no methods for specific local application of active substances to the mucosa of the esophagus to treat eosinophilic esophagitis or other esophageal diseases. This publication describes the principal in vivo functionality and acceptance of a novel modular drug delivery concept, called EsoCap system, by 12 healthy volunteers. For the first time, the EsoCap system enables targeted placement on the esophageal mucosa of a mucoadhesive polymer film. Acceptance was determined by means of a standardized questionnaire after administration and functionality of the device by MRI scans. Two different setups of the EsoCap system were tested: one setup with a density of 0.4 g/cm3 and one with a density of 1.0 g/cm3. Acceptability of the dosage form was also confirmed in addition to functionality, by measuring the applied film length. It was found that acceptance of the variant with the higher density was significantly better. This novel drug delivery technology could enable a targeted, local and long-lasting therapy of the esophagus for the first time, depending on the polymer film used.

scholarly journals Herbal Excipients- Significance of Substances of Natural Origin as Excipients

2020 ◽  
Vol 13 (3) ◽  
pp. 242-252
Author(s):  
S. Selvadurai ◽  
S. Divya ◽  
A. Geetha ◽  
K. Rohini ◽  
S. Anbazhagan
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Drug Absorption ◽  
Drug Delivery Systems ◽  
Dosage Forms ◽  
Natural Origin ◽  
Recent Trends ◽  
Natural Drugs ◽  
Novel Drug ◽  
Delivery Technology

As in every field there is a transformation to improve the performance and satisfy the demand of consumer, in pharmaceutical word, need of “Excipient” have been changed from inert and cheap substance which forms bulk of formulation to a material which has potential to be placed in formulation as it accomplished the desirable objective of treatment. The Herbal or natural excipients have a great advantage over their synthetic analogues as these are non-toxic, less expensive and freely available. Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfill specific functions and in some cases, they directly or indirectly influence the extent and/or rate of drug release and drug absorption. Recent trends towards use of plant based and natural products demand the replacement of synthetic additives with natural ones. Today, the whole world is increasingly interested in natural drugs and excipients, hence natural materials have many advantages over synthetic ones as they are chemically inert, nontoxic, less expensive , biodegradable, improve the shelf life of the product and widely available. This article gives an overview of natural excipients which are used in conventional dosage forms as well as novel drug delivery systems.

scholarly journals A REVIEW ON FAST DISSOLVING TABLET

2018 ◽  
Vol 10 (6) ◽  
pp. 1 ◽  
Author(s):  
Kalindi Chauhan ◽  
Rakesh Solanki ◽  
Shivani Sharma
Keyword(s):  
Drug Delivery ◽  
Dosage Form ◽  
Review Article ◽  
Nineteen Eighties ◽  
Basic Approach ◽  
Croscarmellose Sodium ◽  
Increasing Demand ◽  
Novel Drug ◽  
Mouth Dissolving Tablet ◽  
Delivery Technology

In the present scientific scenario, the drug delivery technology has become extremely competitive and quickly evolving with ever-increasing demand. Fast dissolving tablet (FDT) is one such style of an innovative and distinctive drug delivery system. Once FDT is placed on the tongue, it disintegrates or dissolves quickly (in seconds) without chewing or water. Fast dissolving pills became well-liked because of higher patient compliance and most popular over typical capsules and tablets. Numerous FDT products entered the market in the nineteen eighties. This novel drug delivery like FDT or mouth dissolving tablet (MDT) has overcome several disadvantages like dysphagia or non-accessibility of water whereas travel. Compared with typical dosage form FDT is an alternative as well as helpful for the patient. The basic approach employed in the development of FDT is that the use of superdisintegrants like crosspovidone, croscarmellose sodium or maximizing pore structure within the formulation. This review article contains different techniques used for preparing FDT, silent features, numerous proprietary technologies, mechanism of super disintegration, and also the limitations.

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