scholarly journals A REVIEW ON FAST DISSOLVING TABLET

2018 ◽  
Vol 10 (6) ◽  
pp. 1 ◽  
Author(s):  
Kalindi Chauhan ◽  
Rakesh Solanki ◽  
Shivani Sharma

In the present scientific scenario, the drug delivery technology has become extremely competitive and quickly evolving with ever-increasing demand. Fast dissolving tablet (FDT) is one such style of an innovative and distinctive drug delivery system. Once FDT is placed on the tongue, it disintegrates or dissolves quickly (in seconds) without chewing or water. Fast dissolving pills became well-liked because of higher patient compliance and most popular over typical capsules and tablets. Numerous FDT products entered the market in the nineteen eighties. This novel drug delivery like FDT or mouth dissolving tablet (MDT) has overcome several disadvantages like dysphagia or non-accessibility of water whereas travel. Compared with typical dosage form FDT is an alternative as well as helpful for the patient. The basic approach employed in the development of FDT is that the use of superdisintegrants like crosspovidone, croscarmellose sodium or maximizing pore structure within the formulation. This review article contains different techniques used for preparing FDT, silent features, numerous proprietary technologies, mechanism of super disintegration, and also the limitations.

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Pritam Dinesh Choudhary ◽  
Harshal Ashok Pawar

Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfil specific functions and in some cases they directly or indirectly influence the extent and/or rate of drug release and drug absorption. Recent trends towards use of plant based and natural products demand the replacement of synthetic additives with natural ones. Today, the whole world is increasingly interested in natural drugs and excipients. These natural materials have many advantages over synthetic ones as they are chemically inert, nontoxic, less expensive, biodegradable, and widely available. This review discusses majority of the plant-derived polymeric compounds (gums and mucilage’s), their sources, chemical constituents, uses, and some recent investigations as excipients in novel drug delivery systems.


Author(s):  
Kallem Sharat Venkat Reddy

From the past two decades, technological advancements in science and chemistry made possible many new drug delivery systems that have the potential to completely change the course of routine therapeutic ways.  Lipid and polymer-based drug delivery systems are considered to be the pillars of many drug dosage forms, irrespective of their route of administration. With increasing knowledge on their chemistry, lipids and polymers are being modified and used as potential novel drug delivery systems with smart polymers and lipid nanotechnology paving the way for efficient drug delivery into the patient. This review article covers the swing of these drug delivery systems in the current market and interpreting all this from a health care professional’s point of view. Keywords: Gene delivery, Lipid based drug delivery, Polymer based drug delivery, Target specific drugs, Solid lipid nanoparticles


Pharmatutor ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 58 ◽  
Author(s):  
D. Sharma ◽  
A. A. E. Ali ◽  
J. R. Aate

2013 ◽  
Vol 10 (3) ◽  
pp. 224-232 ◽  
Author(s):  
Devendra Singh Rawat ◽  
Bandana K. Thakur ◽  
Mona Semalty ◽  
Ajay Semalty ◽  
Prabhakar Badoni ◽  
...  

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (03) ◽  
pp. 62-64
Author(s):  
G Chandra Sekhara Rao ◽  
◽  
O. S Aathira ◽  
T. Jyothsna

Fast dissolving tablets are considered as one of the rapidly moving products of novel drug delivery systems in the present pharmaceutical market. The development of new excipients for this technology is challenging task for pharmaceutical technologists. Disintegrants are one of the most important ingredients in the formulation of tablet dosage form. The aim of the present work was to test peanut husk powder, a natural material, as a disintegrant in the formulation of fast dissolving tablets of ondansetron hydrochloride. Tablet evaluation tests like hardness, friability, weight variation, disintegration and dissolution were performed for the prepared tablets. The obtained results were tabulated and they were found to be within the acceptable limits. Among all the formulations, formulation F6 containing peanut husk powder has shown the best disintegration property and based on the results it was found to be a superdisintegrant


2013 ◽  
Vol 171 (2) ◽  
pp. 122-132 ◽  
Author(s):  
Ajazuddin ◽  
Amit Alexander ◽  
Ajita Khichariya ◽  
Saurabh Gupta ◽  
Ravish J. Patel ◽  
...  

2018 ◽  
Vol 10 (6) ◽  
pp. 27 ◽  
Author(s):  
Renuka R. Tiwari ◽  
Dr. M. S. Umashankar ◽  
Damodharan N.

Oral films are gaining a lot of attention as a substitute approach to the conventional dosage form. Over the past few years, many of the pharmaceutical scientists throughout the world are focusing their research on oral films, trying to see the sights of oral films as a novel drug delivery system. The oral films are convenient to swallow for geriatric and pediatric patients, are self-administrable, used for systemic and local action and rapid release of a drug, which makes it an excellent system of drug delivery. This review article mainly discusses the manufacturing aspects of films and their characterization, applications and the constraints in the development of oral films along with highlights of market potential.


2017 ◽  
Vol 112 ◽  
pp. 78-87 ◽  
Author(s):  
Ian Schorn ◽  
Harrison Malinoff ◽  
Steven Anderson ◽  
Cyal Lecy ◽  
Jeffrey Wang ◽  
...  

2016 ◽  
Vol 5 (12) ◽  
pp. 111-117 ◽  
Author(s):  
Muhammad Bilal Hassan Mahboob ◽  
Tehseen Riaz ◽  
Muhammad Jamshaid ◽  
Irfan Bashir ◽  
Saqiba Zulfiqar

In the late 1970s, rapid disintegrating drug delivery system was developed as an alternative to capsules, tablets and syrups for geriatric and pediatric patients having problems in swallowing. To overcome the need, number of orally disintegrating tablets which disintegrate within one minute in mouth without chewing or drinking water were commercialized. Then later, oral drug delivery technology had been improved from conventional dosage form to modified release dosage form and developed recently rapid disintegrating films rather than oral disintegrating tablets. Oral disintegrating film or strips containing water dissolving polymer retain the dosage form to be quickly hydrated by saliva, adhere to mucosa, and disintegrate within a few seconds, dissolve and releases medication for oro-mucosal absorption when placed in mouth. Oral film technology is the alternative route with first pass metabolism. This review give a comprehensive detail of materials used in ODF, manufacturing process, evaluation tests and marketed products.Mahboob et al., International Current Pharmaceutical Journal, November 2016, 5(12): 111-117http://www.icpjonline.com/documents/Vol5Issue12/03.pdf


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