Primary Breast Angiosarcoma: Utilisation of Pre-Surgical Magnetic Resonance Imaging (MRI) for Accurate Tumour Characterization and Planning – A Case Report and Literature Review

Author(s):  
Nazimah Ab Mumin ◽  
Kartini Rahmat ◽  
Marlina Tanty Ramli Hamid ◽  
Ng Wei Lin ◽  
Chan Wai Yee ◽  
...  

Background: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. Case report: A 30-year-old lady presented with left breast pain and lumpiness over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy. Discussion: Literature review on imaging findings of breast angiosarcoma especially on MRI is discussed. MRI features are heterogenous low signal intensity on T1 and high signal intensity in T2. Dynamic contrast enhancement (DCE) features are either early enhancement with or without washout in the delayed phase. Some reported central areas of nonenhancement. Conclusion: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay.

2020 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
ThinThin Win ◽  
SaintNway Aye ◽  
NurulShuhada Abdul Hamad ◽  
SharifahEmilia Tuan Sharif

2000 ◽  
Vol 8 (1) ◽  
pp. 83-87 ◽  
Author(s):  
Tomokazu Ito ◽  
Masahiro Hayashi ◽  
Toshihiko Ogino

Synovial cysts of the cervical spine are extremely rare. We describe an 8-year-old boy with atlantoaxial subluxation and hypoplasia of the dens. Magnetic resonance imaging showed a round lesion, posterior to the odontoid process. This mass was characterized by a low signal intensity on T1-weighted images, and high signal intensity on T2-weighted images. The retrodental synovial cyst disappeared after posterior atlantoaxial arthrodesis.


2020 ◽  
Vol 20 (3) ◽  
pp. 899-903
Author(s):  
Lucas Ribeiro dos Santos ◽  
Márcio Luís Duarte ◽  
Élcio Roberto Duarte ◽  
Felipe Nunes Figueiras

Abstract Introduction: polyorchidism is an unusual pathology, about 200 cases in the world literature. Case report: we reported a case of polyorchidism in a 16-year-old male patient diagnosed by ultrasound and confirmed by magnetic resonance imaging. Discussion: most of the cases presented, there is a supernumerary testis, but there are reports on more than three, up to five testicles with supranumerical gonads on both sides of the scrotum. The diagnosis is usually performed in late puberty, incidentally, with a painless scrotal mass or at the emergency room, presenting a testicular torsion of the whole hemiscrotum or supernumerary testisalone, and the differential diagnosis should be made with epididymal cyst and spermatocele, besides other extra-testicular masses (hydroceles, varicoceles, lipomas, tumors.) and para-testicular masses (hernias, scrotal calculi). After the initial clinical evaluation, ultrasound is the first line subsidiary exam. Magnetic Resonance Imaging is very helpful, just in case the ultrasound diagnosis is uncertain. The supernumerary testishave the same Magnetic Resonance Imaging characteristics as the normal testes (intermediate signal intensity on T1- weighted images and high signal intensity on T2-weighted images).


2007 ◽  
Vol 54 (3) ◽  
pp. 53-57 ◽  
Author(s):  
R. Maksimovic ◽  
P.M. Seferovic ◽  
A.D. Ristic ◽  
T.L. Stosic-Opincal ◽  
M. Kratovac-Dunjic ◽  
...  

Pericardial cysts are uncommon and caused by an incomplete coalescence of fetal lacunae forming the pericardium. The paper presents two cases of pericardial cyst and literature review. The first is a case of a female patient with progressive dispnoa and spherical mass located in the right cardiophrenic angle on a chest x-ray. A pericardial cyst with low signal intensity was noted on T1w, high signal intensity on T2w in TSE (turbo spin echo) sequence on magnetic resonance images (MRI) which was suggestive of serous content. The patient underwent pericardial puncture and was thereafter free of symptoms. Histological study of the cyst confirmed hydatid cyst diagnosis. Another patient is with echocardiographic evidence of cystic formation which was confirmed on MRI, with high signal intensity on SSFP (steady state free precession) sequence. The cyst was without septa and without communication with pericardial space. Since there were no significant hemodynamic changes, the patient is on regular follow up.


2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Motoyoshi Maruyama ◽  
Hiroaki Fushiki ◽  
Yukio Watanabe

We present a case of a solitary neurofibroma of the floor of the mouth protruding into the submandibular region. A 51-year-old female presented with a 2-year history of swelling of the floor of the mouth. MRI revealed that the mass measuring  mm showed a homogenous, low signal intensity on a T1-weighted image and high signal intensity on a T2-weighted image. The tumor was completely removed through a cervical approach. Cases of a solitary neurofibroma originating from the floor of the mouth are extremely rare.


A 79 years old Chinese man presented with 2 episodes of unilateral chorea of left limb (with a short period of bilateral). MRI performed after the onset of the first episode showed multiple old infarctions at bilateral basal ganglia). The first episode lasted about 3 weeks, was resolved after blood glucose better controlled. About 1 week later, he had the second episode. MRI showed high signal intensity on T1-weighted images, low signal intensity on T2-weighted images. This episode was resolved in about 1 week with better glucose control and haloperidol. It suggested that there may be an association of chorea and changes of basal ganglia. So far, there are very limited reports on chorea associated with nonketotic hyperglycemia, only few hundreds of cases reported. It affects elderly type 2 diabetics, is reported more common in Asians. It can be unilateral or bilateral. The pathogenesis remains unclear. Changes of basal ganglia and putamen seems be contributing.


Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Talita Aparecida Riegas Mendes ◽  
Idam de Oliveira

Introduction: Breast lymphoma is a rare variety of this class of tumor in extra-nodal sites, accounting for less than 0.5% of malignant breast neoplasms and less than 3% of extra-nodal lymphomas. The most prevalent type of breast lymphoma is non-Hodgkin lymphoma (NHL) of large B cells. Burkitt lymphoma (BL) occurs in less than 6% of cases and is considered an even rarer subtype of the disease. According to the World Health Organization (WHO), BL can be classified into three clinical forms: endemic (associated with the Epstein-Baar virus), sporadic, and immunodeficiency-related. The clinical presentation of breast lymphoma is similar to that of carcinoma, and imaging tests cannot differentiate them. Objective: This case report aims at providing better knowledge about BL of the breast and conducting a literature review. Case report: A 52-year-old woman with a history of left breast carcinoma (2009) was surgically treated with quadrantectomy, sentinel lymph node biopsy in the left axilla, and adjuvant radiotherapy and hormone therapy. In 2019, she was diagnosed with Human Immunodeficiency Virus (HIV) infection and started antiretroviral therapy (ART). Four months later, she noted nodules in her left breast and underwent imaging and histopathological investigation of the lesions. Immunohistochemical results revealed NHL, with characteristics suggestive of BL of the breast. Positron emission tomography-computed tomography (PET-CT) for disease staging indicated lymphoma in stage IV-A (Ann Arbor Classification, 1988). The patient was admitted by the hematology team of the Hospital de Câncer de Barretos to start chemotherapy. Discussion: BL of the breast affects mainly young women, and its association with the pregnancy/lactation period is not unusual, which suggests a hormonal influence on its development. Secondary breast disease is more common, and differentiating primary and secondary lymphoma can be difficult. When associated with immunodeficiency, it is more frequent in patients infected by HIV, and less in individuals with other immunodeficiency causes. The breast lesion can be characterized by a painless nodule and possible systemic symptoms (sweating, fever, or weight loss). The main management of these cases consists of polychemotherapy, and the benefit of radiotherapy is unclear. Surgical treatments, such as mastectomy, are not indicated and are associated with worse survival. Conclusion: BL of the breast associated with immunodeficiency, concomitant with HIV infection, is an uncommon neoplasm that can progress to a poor prognosis. The appropriate and prompt diagnosis allows starting the best form of treatment and avoids unnecessary surgical procedures.


2021 ◽  
Vol 11 ◽  
Author(s):  
Ying-Shi Sun ◽  
Hui Ci Zhu ◽  
Shi Xing Xu ◽  
Xiao Ting Li ◽  
Zhen Guan ◽  
...  

ObjectiveTo investigate the efficiency of pre-therapy magnetic resonance imaging (MRI) features in predicting the prognosis of desmoid-type fibromatosis patients treated with imatinib.Materials and MethodsA total of 38 desmoid-type fibromatosis patients treated with imatinib were collected in this retrospective study. The high signal intensity on pre-therapy MRI was evaluated on axial T2 and T1 contrast-enhanced sequences with fat suppression. Cox regression and Kaplan–Meier analyses explored the correlation between clinical or radiographic characteristics and progression-free survival (PFS).ResultsHyperintense T1 contrast enhancement (CE) proportion (≥ 75%) was identified as an independent predictor for PFS. Patients with hyperintense T1 CE proportion <75% demonstrated no progression, while patients with hyperintense T1 CE proportion ≥75% demonstrated a progression rate of 78.4%.ConclusionHyperintense T1 CE proportion in the tumor is a potential predictor of disease progression in patients with desmoid-type fibromatosis treated with imatinib. Hyperintense T1 CE proportion <75% indicates progression-free during treatment.


2021 ◽  
Vol 91 (1) ◽  
Author(s):  
Guido Levi ◽  
Nicla Orzes ◽  
Silvia Uccelli ◽  
Francesca Cettolo ◽  
Marianna Arici ◽  
...  

Angiosarcoma is a rare malignancy of vascular origin, mostly originating from skin, soft tissues, and breast, but rarely also from the pleura. We present the case of a 55-year-old man who referred to our hospital for a spontaneous bilateral hemothorax. The CT angiography did not show any source of active bleeding; plus, no pleural or lung masses were observable. Cytological and microbiological analyses made on a sample of pleural fluid resulted negative. Despite numerous blood transfusions and thoracenteses, the patient deceased from hemorrhagic shock ten days later and the diagnosis of primary pleural epithelioid angiosarcoma was obtained only by autopsy. Additionally, we present a review of the literature about primary pleural angiosarcomas.


Pulse ◽  
2015 ◽  
Vol 7 (1) ◽  
pp. 50-52
Author(s):  
FA Ruby ◽  
S Ahsan ◽  
Q Hassan ◽  
M Chandy ◽  
A Parvin

3 months old boy presented with inablility to move upper limb and cries on touching the upper limb from 1 week of age. On examination reflexes were absent in upper limb but hyper reflexia was found in lower limb. Cervical and brain MRI revealed expansion of the cervical spinal canal with smoothly marginated mass within the cervical cord which is hyperintense in T1WI, T2WI and completely loses its signal intensity in FS and gradient weighted sequences. There was no diffusion restriction and appears mostly intramedullary. MRI features were consistent with intramedullary lipoma in cervical spinal cord.Pulse Vol.7 January-December 2014 p.50-52


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