Benign Intracranial Lesions - Radiotherapy: An Overview of Treatment Options, Indications and Therapeutic Results

2020 ◽  
Vol 15 (2) ◽  
pp. 93-121
Author(s):  
Vasileios Tzikoulis ◽  
Areti Gkantaifi ◽  
Filippo Alongi ◽  
Nikolaos Tsoukalas ◽  
Haytham Hamed Saraireh ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Treatment Modality ◽  
Radiation Effects ◽  
Treatment Options ◽  
Proton Beam Therapy ◽  
Tumor Control ◽  
Control Growth ◽  
Effective Treatment Modality ◽  
Intracranial Lesions

Background: Radiation Therapy (RT) is an established treatment option for benign intracranial lesions. The aim of this study is to display an update on the role of RT concerning the most frequent benign brain lesions and tumors. Methods: Published articles about RT and meningiomas, Vestibular Schwannomas (VSs), Pituitary Adenomas (PAs), Arteriovenous Malformations (AVMs) and craniopharyngiomas were reviewed and extracted data were used. Results: In meningiomas RT is applied as an adjuvant therapy, in case of patientrefusing surgery or in unresectable tumors. The available techniques are External Beam RT (EBRT) and stereotactic ones such as Stereotactic Radiosurgery (SRS), Fractionated Stereotactic RT (FSRT), Intensity Modulated RT (IMRT) and proton-beam therapy. The same indications are considered in PAs, in which SRS and FSRT achieve excellent tumor control rate (92-100%), acceptable hormone remission rates (>50%) and decreased Adverse Radiation Effects (AREs). Upon tumor growth or neurological deterioration, RT emerges as alone or adjuvant treatment against VSs, with SRS, FSRT, EBRT or protonbeam therapy presenting excellent tumor control growth (>90%), facial nerve (84-100%), trigeminal nerve (74-99%) and hearing (>50%) preservation. SRS poses an effective treatment modality of certain AVMs, demonstrating a 3-year obliteration rate of 80%. Lastly, a combination of microsurgery and RT presents equal local control and 5-year survival rate (>90%) but improved toxicity profile compared to total resection in case of craniopharyngiomas. Conclusion: RT comprises an effective treatment modality of benign brain and intracranial lesions. By minimizing its AREs with optimal use, RT projects as a potent tool against such diseases.

Role of Girikarnyadi Gutikaanjana in the Management of Krimi Granthi - A Review

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Shwetha G. R. ◽  
Suja K. Sreedhar
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Effective Treatment ◽  
Treatment Modality ◽  
Inflammatory Conditions ◽  
Effective Treatment Modality ◽  
Recurrent Nature

Blepharitis is one of the inflammatory conditions of eyelid caused due to bacterial infection or colonization of the eyelid. It is notorious in nature and also very common, but very annoying to the patients and ophthalmologists too, because of its recurrent nature and lifelong treatment. So it is necessary to find an effective treatment modality. The symptoms of Blepharitis closely resembles to Krimigranthi described in Ayurveda, hence its treatment can be adopted. Girikarnyadi Gutika a Herbo-mineral formulation mentioned in Netra Prakashika consists of Shweta Girikarnika, Shodita Shweta Gunja, Shweta Punarnava, Haridra, Daruharidra, Shodita Tuttha and Gandhaka used as Anjana (application of medicated collyrium to the eye). These drugs are having the properties such as Krimighna (Antihelmintic), Vranaropana (Wound healing), Twakrogahara (cures diseases of skin) and Chakshushya (ocular protective) may be helpful in the management of Blepharitis.

scholarly journals THE EFFECTIVENESS OF USAGE TRIACORTUM, CLOTRIMAZOLE AND DOXYCYCLINE FOR CHRONIC APICAL PERIODONTITIS TREATMENT

World Science ◽  
2019 ◽  
Vol 3 (6(46)) ◽  
pp. 18-21
Author(s):  
Korniichuk O. E.
Keyword(s):  
Effective Treatment ◽  
Treatment Modality ◽  
Antifungal Agent ◽  
Apical Periodontitis ◽  
Clinical Judgement ◽  
Doppler Flowmetry ◽  
Effective Treatment Modality

This article represents the work for searching new and effective treatment modality for chronic forms of periodontitis with application of the antibiotic doxycycline, antifungal agent clotrimazole and glucocorticosteroid triacortum.It was made the clinical judgement of treatment of 150 patients with chronic apical periodontitis. It was indicated an improvement of microcirculation in periodontitis tissue by Lazer Doppler flowmetry method by those patients who received therapy using proposed method of treatment and set of medication.

scholarly journals The Role of Hypoxia and the Immune System in Tumor Radioresistance

Cancers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1555 ◽  
Author(s):  
Paul Span ◽  
Jan Bussink
Keyword(s):  
Immune System ◽  
Effective Treatment ◽  
Treatment Options ◽  
Cost Effective ◽  
Patients With Cancer ◽  
Cost Effective Treatment

Radiotherapy is given to a majority of patients with cancer, and remains one of the most (cost)effective treatment options available [...]

Total contact casting

1995 ◽  
Vol 85 (3) ◽  
pp. 172-176 ◽  
Author(s):  
RE Baker
Keyword(s):  
Effective Treatment ◽  
Diabetic Foot ◽  
Treatment Modality ◽  
Treatment Method ◽  
Complex Treatment ◽  
Effective Treatment Modality ◽  
Total Contact Casting ◽  
Neuropathic Foot

The treatment of diabetic foot ulcerations has been a difficult task for podiatrists. Numerous methods and materials have been used in an attempt to alleviate this frustrating and complex treatment dilemma. However, there is one treatment method that has been used successfully for decades on plantar ulcerations of the neuropathic foot. Total contact casting has been an easily applicable and effective treatment modality for neuropathic ulcerations of the diabetic foot.

Diagnosis of Metastatic Breast Cancer—A Case Report Using Molecular Cancer Classification

2011 ◽  
Vol 07 (02) ◽  
pp. 116
Author(s):  
Yogesh Gandhi ◽  
Sunil Gandhi ◽  
◽  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Effective Treatment ◽  
Cancer Diagnosis ◽  
Treatment Options ◽  
Metastatic Breast ◽  
Complete Response ◽  
Molecular Profiling ◽  
History Of

An accurate cancer diagnosis is critical as it can direct the use of site-directed, and potentially more effective, treatment options for specific types of cancer. A differential or uncertain diagnosis could prevent cancer patients from receiving optimal treatment, thus affecting their overall prognosis. Advances in molecular technology have led to the development of molecular cancer classifiers that can direct or confirm the diagnosis of metastatic cancers which would otherwise be considered uncertain or unknown. This case report describes the role of molecular diagnostics in the evaluation of a patient with a large pancreatic mass and a history of breast cancer. Results from a 92-gene molecular profiling assay (CancerTYPE ID®) predicted that this new mass was breast cancer. This diagnosis allowed for effective treatment and complete response in this patient.

Peroral Endoscopic Myotomy (POEM) Is an Effective Treatment Modality for All Subtypes of Achalasia

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S236-S237
Author(s):  
Madhusudhan R. Sanaka ◽  
Malav P. Parikh ◽  
Subanandhini Subramaniam ◽  
Prasanthi N. Thota ◽  
Niyati M. Gupta ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Treatment Modality ◽  
Peroral Endoscopic Myotomy ◽  
Effective Treatment Modality ◽  
Endoscopic Myotomy
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