Computational and Functional Analysis of the Androgen Receptor Antagonist Atraric Acid and Its Derivatives

Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC)

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.0c01563 ◽

2021 ◽

Vol 64 (2) ◽

pp. 909-924 ◽

Cited By ~ 1

Author(s):

Zhuming Zhang ◽

Peter J. Connolly ◽

Heng Keang Lim ◽

Vineet Pande ◽

Lieven Meerpoel ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Receptor Antagonist ◽

Clinical Stage ◽

Castration Resistant Prostate Cancer ◽

Wild Type ◽

Castration Resistant

Androgen receptor antagonist impairs courtship but not aggressive behavior in the monogamous cichlid, Amatitlania nigrofasciata

Hormones and Behavior ◽

10.1016/j.yhbeh.2013.01.008 ◽

2013 ◽

Vol 63 (3) ◽

pp. 527-532 ◽

Cited By ~ 9

Author(s):

Natalie April van Breukelen

Keyword(s):

Androgen Receptor ◽

Aggressive Behavior ◽

Receptor Antagonist ◽

Amatitlania Nigrofasciata

Enzalutamide, an Androgen Receptor Antagonist, Enhances Myeloid Cell–Mediated Immune Suppression and Tumor Progression

Cancer Immunology Research ◽

10.1158/2326-6066.cir-19-0371 ◽

2020 ◽

Vol 8 (9) ◽

pp. 1215-1227 ◽

Cited By ~ 2

Author(s):

Camila R. Consiglio ◽

Olga Udartseva ◽

Kimberly D. Ramsey ◽

Chioma Bush ◽

Sandra O. Gollnick

Keyword(s):

Androgen Receptor ◽

Tumor Progression ◽

Receptor Antagonist ◽

Immune Suppression ◽

Myeloid Cell ◽

Correction to Total Synthesis of the Potent Androgen Receptor Antagonist (−)-Arabilin: A Strategic, Biomimetic [1,7]-Hydrogen Shift

Journal of the American Chemical Society ◽

10.1021/ja2116958 ◽

2012 ◽

Vol 134 (9) ◽

pp. 4449-4449 ◽

Cited By ~ 1

Author(s):

Hee Nam Lim ◽

Kathlyn A. Parker

Keyword(s):

Androgen Receptor ◽

Total Synthesis ◽

Receptor Antagonist ◽

Hydrogen Shift ◽

Abstract PR09: TAS3681, a new type androgen receptor antagonist, suppresses ligand-independent AR activation through its AR downregulation activity

10.1158/1535-7163.targ-15-pr09 ◽

2015 ◽

Author(s):

Daisuke Kajiwara ◽

Kazuhisa Minamiguchi ◽

Masanao Seki ◽

Hiroya Mizutani ◽

Hiroki Aoyagi ◽

...

Keyword(s):

Androgen Receptor ◽

Receptor Antagonist ◽

New Type

Abstract 3885: Evaluation of pharmacokinetics of proxalutamide, a novel androgen receptor antagonist, in treatment for mCRPC patients via CTC enumeration and AR biomarker analysis

10.1158/1538-7445.sabcs18-3885 ◽

2019 ◽

Author(s):

Lincy Chu ◽

Phoebe Zhang ◽

Amanda Anderson ◽

Mark Landers ◽

Yipeng Wang ◽

...

Keyword(s):

Androgen Receptor ◽

Receptor Antagonist ◽

Biomarker Analysis

P01.068 The anti-tumor effect of androgen receptor antagonist on GBM may result, at least partially, through attenuation of CDK4 and CDC14a expression

Neuro-Oncology ◽

10.1093/neuonc/noy139.110 ◽

2018 ◽

Vol 20 (suppl_3) ◽

pp. iii245-iii245

Author(s):

N Zalcman ◽

A Mordechai ◽

A Lossos ◽

I Lavon

Keyword(s):

Androgen Receptor ◽

Receptor Antagonist ◽

The androgen receptor antagonist enzalutamide induces apoptosis, dysregulates the heat shock protein system, and diminishes the androgen receptor and estrogen receptor β1 expression in prostate cancer cells

Journal of Cellular Biochemistry ◽

10.1002/jcb.28929 ◽

2019 ◽

Vol 120 (10) ◽

pp. 16711-16722

Author(s):

Alexander Abazid ◽

Benedikt Martin ◽

Anja Choinowski ◽

Rhiannon V. McNeill ◽

Lars‐Ove Brandenburg ◽

...

Keyword(s):

Prostate Cancer ◽

Estrogen Receptor ◽

Androgen Receptor ◽

Heat Shock ◽

Heat Shock Protein ◽

Receptor Antagonist ◽

Cancer Cells ◽

Prostate Cancer Cells ◽

Protein System ◽

Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-06-0144 ◽

2007 ◽

Vol 6 (1) ◽

pp. 51-60 ◽

Cited By ~ 73

Author(s):

Deborah L. Marrocco ◽

Wayne D. Tilley ◽

Tina Bianco-Miotto ◽

Andreas Evdokiou ◽

Howard I. Scher ◽

...

Keyword(s):

Prostate Cancer ◽

Cell Proliferation ◽

Androgen Receptor ◽

Receptor Antagonist ◽

Hydroxamic Acid ◽

Prostate Cancer Cell ◽

Receptor Expression ◽

Suberoylanilide Hydroxamic Acid ◽

Cancer Cell Proliferation ◽

Persistent DDT Metabolite p,p'-DDE is a Potent Androgen Receptor Antagonist

Obstetrical & Gynecological Survey ◽

10.1097/00006254-199602000-00020 ◽

1996 ◽

Vol 51 (2) ◽

pp. 111-114 ◽

Cited By ~ 3

Author(s):

William R. Kelce ◽

Christy R. Stone ◽

Susan C. Laws ◽

Earl L. Gray ◽

Jon A. Kemppainen ◽

...

Keyword(s):

Androgen Receptor ◽

Receptor Antagonist ◽