Assessment of Posterior Segment Using Spectral Domain OCT in Highly Myopic Eyes

Purpose: Spectral Domain Optical Coherence Tomography (SD-OCT) was used to evaluate retinal and vitreo-retinal changes that occur in highly myopic patients. Methods: This prospective study included 472 eyes of 472 patients suffering from high myopia (> -6.00 D), between May 2012 and December 2015. All patients were examined, using Cirrus HD OCT (Zeiss Cirrus TM HD-OCT model 4000), to detect any retinal or vitreo-retinal interface abnormalities. All obtained data was analyzed using Statistical Package for the Social Sciences software version 17 (SPSS Inc, Chicago, IL, USA) and the paired two-sided t-test. Bivariate correlations were performed between different parameters using the Spearman correlation coefficient (r). Results: Mean spherical equivalent (MSE) was -13.11± 4.35D. Mean axial length (AL) was 28.5±1.62 mm. Posterior vitreous detachment (PVD) was the most frequent OCT finding; representing 33.4% of the cases, 13.7% of them were associated with macular traction. A statistically significant positive correlation was found between AL and MTM, full thickness macular hole, PVD with traction, and dome shaped macula (r = 0.49 and P = 0.001, r = 0.422 and P = 0.0001, r = 0.25 and P = 0.03, r=0.475, P=0.001 respectively) Conclusion: OCT is a valuable tool in detecting retinal and vitreo-retinal interface abnormalities in highly myopic eyes, and it can be used for follow up of those patients to avoid advanced retinal damage.

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Clinical and Spectral-Domain Optical Coherence Tomography Findings of Patients with Incomplete Visual Recovery after Anatomically Successful Retinal Detachment Surgery

Journal of Ophthalmology ◽

10.1155/2015/420401 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Miltiadis K. Tsilimbaris ◽

Aikaterini Chalkia ◽

Chrysanthi Tsika ◽

Anastasios Anastasakis ◽

Georgios A. Kontadakis

Keyword(s):

Retinal Detachment ◽

Spectral Domain ◽

Strongly Correlated ◽

Visual Recovery ◽

Retinal Detachment Surgery ◽

Spectral Domain Oct ◽

Pars Plana ◽

Oct Imaging ◽

Sd Oct

Purpose. To identify causes of incomplete visual recovery in patients with anatomically successful retinal detachment surgery.Methods. This was a retrospective study of 61 eyes of 61 patients with at least 12-month follow-up and complete preoperative, intraoperative, and postoperative record. Postoperative visual acuity (VA) more than 0.18 logMAR was considered as incomplete visual recovery. Complete ophthalmic examination and Spectral-Domain OCT (SD-OCT) imaging were performed at last follow-up.Results. Twenty-nine eyes (47.5%) had a postoperative VA < 0.18 logMAR and 32 eyes (52.5%) had a postoperative VA ≥ 0.18 logMAR. Mean follow-up was 32.8 ± 17.3 months. Incomplete visual recovery was strongly correlated with presence of macular pathology (P= 0.002), a detached macula preoperatively (P= 0.02), retinotomy (P= 0.025), and pars plana vitrectomy and use of silicon oil as a tamponade agent (P= 0.009). Also, although there was a strong correlation between ellipsoid zone disruption and incomplete visual recovery, a distinct, more course pathology could be identified in all cases of poor visual recovery related to edema, thickening, or atrophy of the macula.Conclusion. The careful postoperative evaluation of the macula using biomicroscopy and SD-OCT can help in diagnosis of alterations that can be associated with incomplete visual recovery.

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In vivo Evaluation of Zirconia Abutments in Implant supported Restorations in Partially Edentulous Patients

Journal of Contemporary Dentistry ◽

10.5005/jp-journals-10031-1182 ◽

2017 ◽

Vol 7 (1) ◽

pp. 35-42

Author(s):

Anita Kapri ◽

Sudhir Joshi

Keyword(s):

Social Sciences ◽

Titanium Implants ◽

P Value ◽

In Vivo Evaluation ◽

The Social ◽

Scale Scores ◽

Edentulous Patients ◽

Biological Outcomes

ABSTRACT Dental implants have been a universally accepted option for prosthetic rehabilitation of partially edentulous patients. Titanium implants abutments exhibit a dull grayish hue and give an unnatural appearance. Abutments based on zirconia are one of the alternatives to titanium abutments. To date, few comparative studies have reported on esthetic and biological outcomes of implant-supported restorations with zirconia abutments. Purpose To clinically evaluate the esthetic performance of zirconia abutments in implant-supported restorations. Materials and methods A total of 24 anterior implant sites were chosen for the placement of implants. A delayed loading protocol was followed; 12 zirconia abutments were placed along with 12 titanium abutments in the contralateral sites. Biological and esthetic variables were recorded by a periodontist and prosthodontist. The patients were followed 2 weeks, 1, 3, and 6 months postinsertion. Results All the data for Copenhagen index score and visual analog scale scores were evaluated by the prosthodontist at follow-up appointments; the means were tabulated. The data were statistically analyzed using Statistical Package for the Social Sciences software utilizing paired t-test; p value was found to be significant for all parameters except distal papilla and symmetry, which showed p = 0.257 and p = 0.110 respectively. Conclusion According to the results of this study, esthetic performances of zirconia abutment in implant-supported restorations were determined to be higher than those values associated with titanium abutments. How to cite this article Kapri A, Gupta A, Joshi S. In vivo Evaluation of Zirconia Abutments in Implant supported Restorations in Partially Edentulous Patients. J Contemp Dent 2017;7(1):35-42.

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Korrelation der quantitativen Metamorphopsiemessung und der zentralen Netzhautdicke bei diabetischem Makulaödem und altersassoziierter exsudativer Makuladegeneration

Klinische Monatsblätter für Augenheilkunde ◽

10.1055/s-0043-125080 ◽

2018 ◽

Vol 236 (07) ◽

pp. 877-884 ◽

Cited By ~ 2

Author(s):

Daniela Claessens ◽

Alexander K. Schuster

Keyword(s):

Spectral Domain ◽

Sich Eine ◽

Spectral Domain Oct ◽

Sd Oct

Zusammenfassung Hintergrund Zur Erfassung von Metamorphopsien steht im klinischen Alltag der Amsler-Test zur Verfügung. Dieser erfasst qualitativ Metamorphopsien, zur Quantifizierung von Metamorphopsien und als Verlaufskontrolle wurde der computerbasierte Test „AMD – A Metamorphopsia Detector®“ entwickelt. Das Ziel dieser Studie ist zu untersuchen, ob eine Korrelation zwischen zentraler Netzhautdicke (CRT, gemessen mittels Spectral Domain OCT) und quantifizierter Metamorphopsiemessung bei Patienten mit exsudativer altersassoziierter Makuladegeneration (AMD) und diabetischem Makulaödem (DMÖ) besteht. Material und Methoden 66 Augen von 66 Patienten (DMÖ: 19 [11 Männer, 8 Frauen; Alter 42 – 76 Jahre]; AMD: 47 [13 Männer, 34 Frauen; Alter 56 – 93 Jahre]) wurden in dieser explorativen Pilotstudie untersucht und in Hinblick auf das Vorliegen eines Makulaödems (zentrale 500-µm-Zone, Cirrus HD-OCT) klassifiziert. Bestkorrigierter monokularer Fernvisus (BCVA), Amsler-Test, Metamorphopsiemessung (AMD – A Metamorphopsia Detector) mit Angabe des Metamorphopsie-Index (MI), binokulare Ophthalmoskopie, SD-OCT mit Messung der zentralen Netzhautdicke (CRT) und ggf. Fluoreszenzangiografie wurden durchgeführt. Die Korrelation von CRT und MI wurde mittels Spearman-Korrelation geprüft. Ergebnisse BCVA bei DMÖ bzw. AMD betrug (logMAR) 0,27 (SD 0,3) bzw. 0,29 (SD 0,2). Bei Augen mit DMÖ zeigte sich eine Korrelation von MI und CRT mit rho = 0,88 (p < 0,001) und bei Augen mit AMD betrug rho = 0,56 (p < 0,001). Schlussfolgerung Die Korrelation von CRT und MI war bei DMÖ hoch und bei AMD moderat. Künftige Studien sollen untersuchen, ob sich die Metamorphopsiemessung zur Detektion einer Konversion in eine exsudative AMD eignet und ob dies eine Messung zur Verlaufskontrolle, ggf. als Selbsttest ermöglicht.

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Spectral Domain Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Interface Pathologies

Journal of Ophthalmology ◽

10.1155/2012/876472 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 24

Author(s):

Yoreh Barak ◽

Mark A. Ihnen ◽

Shlomit Schaal

Keyword(s):

Optical Coherence Tomography ◽

Image Interpretation ◽

Posterior Vitreous Detachment ◽

Spectral Domain ◽

Optical Coherence ◽

Vitreoretinal Interface ◽

Epiretinal Membranes ◽

Macular Holes ◽

Practice Knowledge ◽

Sd Oct

The introduction of spectral domain optical coherence tomography (SD-OCT) has enhanced Vitreoretinal Interface (VRI) imaging considerably and facilitated the diagnosis, followup, prognosis determination, and management of VRI-associated pathologies. HR-OCT became a common practical tool seen in almost every ophthalmology practice. Knowledge of SD-OCT image interpretation and recognition of pathologies are required for all ophthalmologists. This paper methodically reviews the normal aging process of the VRI and discusses several commonly encountered VRI pathologies. The role of SD-OCT imaging in VRI-associated disorders such as posterior vitreous detachment, vitreomacular traction syndrome, idiopathic epiretinal membranes, lamellar holes, pseudoholes, and full thickness macular holes is portrayed. Future perspectives of new OCT technologies based on SD-OCT are discussed.

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“En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome

Journal of Ophthalmology ◽

10.1155/2014/928028 ◽

2014 ◽

Vol 2014 ◽

pp. 1-6 ◽

Cited By ~ 16

Author(s):

Flore De bats ◽

Benjamin Wolff ◽

Vivien Vasseur ◽

Aude Affortit ◽

Laurent Kodjikian ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Spectral Domain ◽

Enhanced Depth Imaging ◽

Optical Coherence ◽

Retinal Layers ◽

White Dot Syndrome ◽

En Face Oct ◽

En Face ◽

Sd Oct

Purpose. The recent use of “en-face” enhanced-depth imaging spectral-domain optical coherence tomography (EDI SD-OCT) helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome (MEWDS).Methods. Four patients presenting with MEWDS underwent a comprehensive ocular examination including C-scan (“en-face”) EDI SD-OCT at the initial visit and during follow-up.Results. C-scans combined with the other multimodal imaging enabled the visualization of retinal damage. Acute lesions appeared as diffuse and focal disruptions occurring in the ellipsoid and interdigitation zones. The match between autofluorescence imaging, indocyanine green angiography, and “en-face” OCT helped identify the acute microstructural damages in the outer retina further than the choroid. Follow-up using “en-face” EDI-OCT revealed progressive and complete recovery of the central outer retinal layers.Conclusion. “En-face” EDI SD-OCT identified the site of initial damage in MEWDS as the photoreceptors and the interdigitation layers rather than the choroid. Moreover, “en-face” OCT is helpful in the follow-up of these lesions by being able to show the recovery of the outer retinal layers.

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Corneal and Epithelial Thickness Mapping: Comparison of Swept-Source- and Spectral-Domain-Optical Coherence Tomography

Journal of Ophthalmology ◽

10.1155/2021/3444083 ◽

2021 ◽

Vol 2021 ◽

pp. 1-6

Author(s):

Cristina Georgeon ◽

Ilanite Marciano ◽

Roxane Cuyaubère ◽

Otman Sandali ◽

Nacim Bouheraoua ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Corneal Thickness ◽

Spectral Domain ◽

Lamellar Keratoplasty ◽

Optical Coherence ◽

Swept Source ◽

Epithelial Thickness ◽

Spectral Domain Oct ◽

Anterior Lamellar Keratoplasty ◽

Sd Oct

Objective. To compare the results and repeatability of the corneal thickness (CT) and epithelial thickness (ET) maps provided by Swept-Source-Optical Coherence Tomography with those of Spectral-Domain-OCT in normal eyes. Methods. 30 normal eyes of 30 patients were assessed by 3 trained operators with SS-OCT and SD-OCT. Results. The central and minimum ET obtained with both devices were correlated: central ET, r = 0.86, p < 0.05 ; minimum ET, r = 0.72, p < 0.05 . Compared with SD-OCT, SS-OCT tended to underestimate these figures by 1.4 and 1.9 μm on average. The central and minimum CT obtained with both devices were strongly correlated: central CT, r = 0.994, p < 0.05 ; minimum CT, r = 0.995, p < 0.05 . SS-OCT tended to overestimate these figures by 11 and 14 μm on average. Repeatability was good for both devices with a mean coefficient of variation of measurements <6% for ET and <2% for CT. Interoperator variability (standard deviation and COV) was significantly higher for SS-OCT than for SD-OCT for all local epithelial thicknesses and significantly lower for the central CT and several local corneal thicknesses, whereas no significant differences between both technologies were found for the central and minimum ET and the minimum CT. Conclusion. SS-OCT and SD-OCT provide reproducible measurements of CT and ET in normal corneas with a strong correlation between both technologies. However, both technologies are not interchangeable when the main thickness parameters (i.e., central and minimum CT and minimum ET) are used for diagnosing early keratoconus or calculating the expected residual stromal bed thickness before corneal refractive surgery or anterior lamellar keratoplasty.

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AMD edemas: diagnosis, follow-up, therapeutic, prognosis, spectral domain OCT, fluorescein, ICG angiographies interests

Acta Ophthalmologica ◽

10.1111/j.1755-3768.2010.288.x ◽

2010 ◽

Vol 88 ◽

pp. 0-0

Author(s):

C GONZALEZ

Keyword(s):

Spectral Domain ◽

Spectral Domain Oct

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Low-Reflectivity Drusen With Overlying RPE Damage Revealed by Spectral-Domain OCT: Hint for the Development of Age-Related Macular Degeneration

Frontiers in Medicine ◽

10.3389/fmed.2021.706502 ◽

2021 ◽

Vol 8 ◽

Author(s):

Shasha Yang ◽

Zongyin Gao ◽

Haijiang Qiu ◽

Chengguo Zuo ◽

Lan Mi ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Macular Degeneration ◽

Retinal Pigment ◽

Morphological Characteristics ◽

Age Related Macular Degeneration ◽

Spectral Domain ◽

Optical Coherence ◽

Age Related ◽

Sd Oct

Purpose: To observe the relationship between the characteristic changes in the drusen morphology revealed by the spectral-domain optical coherence tomography (SD-OCT) and the progression of age-related macular degeneration (AMD).Methods: A total of 380 drusen in 45 eyes in 35 patients with the intermediate drusen were longitudinally followed up every 6 months by SD-OCT for a period of 24 months. The drusen were divided into the dynamic group and stable group according to the following parameters: number, volume, concurrent retinal pigment epithelium (RPE)/ellipsoid zone (EZ) damage, and the development of advanced AMD. The morphological characteristics of the progressive or stable drusen were further analyzed. Odds ratios (ORs) and the risk for the drusen progression were calculated.Results: The level of interobserver and intraobserver agreement for each drusen tomographic morphological parameters ranged from 82.7 to 90%. At the end of an average follow-up of 15.92 ± 6.99 months, six patients developed choroidal neovascularization and no patients developed geographic atrophy. Finally, 139 drusen changed and 241 drusen remained stable. The drusen with low reflectivity (p < 0.001; OR: 5.26; 95% CI: 2.24–12.36), non-homogeneity without a core (p < 0.001; OR: 4.31; 95% CI: 2.08–8.92), RPE damage (p < 0.001; OR: 28.12; 95% CI: 9.43–83.85), and the EZ damage (p < 0.001; OR: 14.01; 95% CI: 5.28–37.18) were significantly associated with active change; the drusen with low reflectivity (p = 0.01; OR: 2.95; 95% CI: 1.29–6.75) and decreased overlying RPE reflectivity (p < 0.001; OR: 21.67; 95% CI: 9.20–51.02) were the independent predictors for progression. The drusen with high reflectivity were significantly associated with stabilization (p = 0.03; OR: 0.17; 95% CI: 0.04–0.84).Conclusion: Spectral-domain optical coherence tomography is an optimized, accurate, and efficient method to follow-up the drusen. The intermediate non-exudative AMD prognosis of the patient was most strongly correlated with the drusen reflectivity and disruption of the overlying RPE layer. The drusen with low reflectivity and overlying RPE damage were more likely to progress and required frequent follow-up.

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Functional and morphological outcomes after surgery in lamellar macular holes versus epiretinal membrane foveoschisis

European Journal of Ophthalmology ◽

10.1177/1120672120974287 ◽

2020 ◽

pp. 112067212097428

Author(s):

Luigi Caretti ◽

Alvise La Gloria Valerio ◽

Giacomo Verzola ◽

Gloria Badin ◽

Cristina Monterosso ◽

...

Keyword(s):

Epiretinal Membrane ◽

Clinical Findings ◽

Functional Improvement ◽

Foveal Thickness ◽

Central Foveal Thickness ◽

Macular Holes ◽

Full Thickness Macular Hole ◽

Anatomical Success ◽

Sd Oct

Purpose: To compare the clinical findings and outcomes of vitrectomy for lamellar macular holes (LMH) versus epiretinal membrane foveoschisis (ERMF). Materials and methods: This retrospective study enrolled 36 eyes of 35 patients with a minimum follow-up of 6 months. Spectral domain optical coherence tomography (SD-OCT) parameters and best-corrected visual acuity (BCVA) were analyzed preoperatively and postoperatively. Results: The 19 (52.8%) ERMF and 17 (47.2%) LMH were included. Preoperatively, eyes with LMH were characterized by a lower central foveal thickness (CFT) (102.18 ± 31.44 µm vs 159.37 ± 25.25 µm, p < 0.001) and a greater incidence of outer retinal disruption ( p < 0.001). Primary anatomical success was achieved in 34/36 eyes (94.4%). Preoperative BCVA was better in ERMF (0.16 – IQR 0.09 – logarithm of the minimal angle of resolution (LogMAR) – 20/28 Snellen) than LMH (0.40 – IQR 0.30 – LogMAR, 20/50 Snellen) ( p = 0.008). At 6 months after surgery, BCVA significantly improved in the ERMF group ( p < 0.001), but showed insignificant change in LMH ( p = 0.125). Two cases, both in the LMH group, developed full thickness macular hole after surgery. Conclusion: Eyes with LMH showed visual stabilization after surgery, whereas the eyes in the ERMF group were susceptible to functional improvement. These differences in BCVA outcomes may be the consequence of a higher damage in the outer retina in the LMH group; an accurate SD-OCT examination is a fundamental step when deciding to proceed or not to the surgery.

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