scholarly journals Role of Age and Sex on Simple and Complex Carbohydrates Rich Foods Consumption and Thyroid Cancer Risk: Hospital Based Case - Control Study

2021 ◽  
Vol 14 (1) ◽  
pp. 38-44
Author(s):  
Maria Fiore ◽  
Antonio Cristaldi ◽  
Valeria Okatyeva ◽  
Salvatore Lo Bianco ◽  
Gea Oliveri Conti ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Thyroid Cancer Risk ◽  
Complex Carbohydrates ◽  
Simple Carbohydrates ◽  
Control Study ◽  
Age And Sex

Background: The risk of thyroid cancer has already been related to diet/carbohydrates rich foods, but the association has not been investigated in terms of age and sex implications. Objective: We studied the relationship between thyroid cancer and the consumption of simply and complex carbohydrates rich foods, mainly investigating the possible predictive role of age and sex. Methods: We analyzed data from a hospital case-control study conducted in Italy from 2015 to 2018, including 106 cases of thyroid cancer and 121 controls. The consumption of simple and complex carbohydrates rich foods was investigated through the validated Lifestyles Questionnaire using a 4-level scale (never, 1 time per week, 2–3 times a week, 6 times a week). Statistical data analysis was conducted using the IBM SPSS Statistics 21.0 program. Results: We found a moderate negative correlation between simple carbohydrates rich foods consumption and age (rho= -0.364, p:0.00), particularly in females (females: rho= -0.374, p:0.00; males: rho=-0.266, p=0.036). A weak positive correlation was found between age and complex carbohydrates-rich foods only in males (rho= 0.244, p=0.054). The Two-Way Analysis of Variance confirmed that, overall, simple carbohydrates rich foods consumption decreased with age categories (Case: F=2.59, p=0.032; Control: F=3.14, p=0.011), although it remains higher for female than male cases at all age categories (≤38, 39-52, 53+years). Conversely the complex carbohydrates rich foods intake had interaction with age categories only in controls group (Control: F=1.95, p=0.09; Case: F=0.744, p=0.592), where based on sex, it remains higher for female than male at ≤38 and 39-52 age categories. It should be emphasized that in category ≤38 we had only one male cases. Conclusion: Our study adds new and relevant information to support the hypothesis that age and sex could impact the thyroid cancer risk by their involvement in simple carbohydrates rich foods consumption. Therefore, future interventions are needed for an understanding of the pathophysiological associations between only carbohydrates rich foods intake and thyroid cancer, mainly for older and female populations, and also for the improvement of preventive public health policies and “Gender Medicine”.

scholarly journals The effect of raw vegetable and fruit intake on thyroid cancer risk among women: a case–control study in South Korea

2012 ◽  
Vol 109 (1) ◽  
pp. 118-128 ◽  
Author(s):  
Su Kyoung Jung ◽  
Kirang Kim ◽  
Kyung Tae ◽  
Gu Kong ◽  
Mi Kyung Kim
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Early Stage ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Dietary Factors ◽  
Inverse Association ◽  
Thyroid Cancer Risk ◽  
Control Study

Thyroid cancer is the most common cancer among Korean women. However, there are few data on dietary factors related to thyroid cancer risk. The objective of the present study was to evaluate the association between raw vegetables and fruits intake and thyroid cancer in a case–control study. We included 111 histologically confirmed malignant thyroid cancer cases and 115 benign cases. Controls who did not have nodules in thyroid ultrasonography were matched to cases by age ( ± 2 years). Food and nutrient intakes were estimated using a quantitative FFQ with 121 items. Conditional logistic regression analysis was used to obtain OR and corresponding 95 % CI. The intake of total vegetables was not associated with malignant thyroid cancer, but inversely associated with benign cases. High raw vegetable intake was inversely associated with thyroid cancer risk both in malignant and benign cases (P for trend = 0·01 in both malignant and benign cases). Among fruits, persimmon intake had an inverse association with thyroid cancer risk in both malignant and benign cases (P for trend = 0·06 in malignant cases; P for trend = 0·01 in benign cases) and tangerine intake had an inverse association in malignant cases (P for trend = 0·03). The frequency of consumption of raw vegetables and persimmon also had a consistent inverse association in both malignant and benign cases. These results suggest that high consumption of raw vegetables, persimmons and tangerines may decrease thyroid cancer risk and help prevent early-stage thyroid cancer.

scholarly journals Dietary habits and thyroid cancer risk: A hospital-based case–control study in Sicily (South Italy)

2020 ◽  
Vol 146 ◽  
pp. 111778
Author(s):  
Maria Fiore ◽  
Antonio Cristaldi ◽  
Valeria Okatyeva ◽  
Salvatore Lo Bianco ◽  
Gea Oliveri Conti ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Dietary Habits ◽  
Case Control ◽  
South Italy ◽  
Thyroid Cancer Risk ◽  
Control Study

scholarly journals Lack of Association between Fingernail Selenium and Thyroid Cancer Risk: A Case-Control Study in French Polynesia

2014 ◽  
Vol 15 (13) ◽  
pp. 5187-5194 ◽  
Author(s):  
Yan Ren ◽  
Cari Meinhold Kitahara ◽  
Amy Berrington de Gonzalez ◽  
Enora Clero ◽  
Pauline Brindel ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
French Polynesia ◽  
Case Control ◽  
Thyroid Cancer Risk ◽  
Control Study

scholarly journals Use of Dietary Vitamin Supplements and Risk of Thyroid Cancer: A Population-Based Case-Control Study in Connecticut

2016 ◽  
Vol 86 (5-6) ◽  
pp. 189-197
Author(s):  
Christopher Kim ◽  
Huang Huang ◽  
Nan Zhao ◽  
Catherine C. Lerro ◽  
Min Dai ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Dietary Supplements ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Papillary Thyroid ◽  
Calcium Supplements ◽  
Thyroid Cancer Risk ◽  
Control Study

Abstract. Certain dietary supplements have been reported to increase the risk of some cancers. Over half of the US population regularly uses dietary supplements. Thyroid cancer incidence has increased over the past several decades. However, few studies have investigated the association between dietary supplements and thyroid cancer. Thus, it is essential to clarify any association between dietary supplements and risk of thyroid cancer. Materials and methods: A population-based case-control study in Connecticut was conducted during 2010–2011 among 462 histologically confi rmed incident thyroid cancer cases and 498 population-based controls. Dietary supplement intake was ascertained through in-person interviews and a food frequency questionnaire. Multivariate unconditional logistic regression models were used to estimate the risk of thyroid cancer and dietary supplement use. Results: Overall, no statistically signifi cant associations were observed between dietary supplementation and thyroid cancer risk. Stratifi ed analyses revealed a suggestive protective effect on risk of papillary microcarcinoma among longterm (> 10 years) use of multivitamins (OR = 0.59, 95 % CI: 0.33, 1.04) and calcium supplementation (OR = 0.45, 95 % CI: 0.22, 0.93). An increased risk of large papillary thyroid cancers (tumor size > 1 cm) was observed among short-term (< 5 years) users of calcium supplements (OR = 2.24, 95 % CI: 1.30, 3.88). Discussion: No signifi cant associations were observed between supplementation and overall thyroid cancer risk. The different associations between calcium supplements and risk of papillary thyroid cancer by tumor size warrant further investigation.

scholarly journals 1107Dietary polyphenol intake and differentiated thyroid cancer risk: a population-based case-control study in New Caledonia

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Melanie Paquet ◽  
Dominique Baron-Dubourdieu ◽  
Pascal Guénel ◽  
Thérèse Truong
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Differentiated Thyroid Cancer ◽  
Case Control Study ◽  
New Caledonia ◽  
Population Based ◽  
Case Control ◽  
Thyroid Cancer Risk ◽  
Polyphenol Intake ◽  
Control Study

Abstract Background Aetiology of differentiated thyroid cancer is poorly understood. Among the risk factors strongly suspected to be involved in thyroid carcinogenesis are dietary factors. Recent evidence suggests polyphenols (i.e., natural bioactive compounds found in plant species), and their anticancer properties, may deserve closer epidemiological attention. Therefore, we examined the association between polyphenol intake levels and thyroid cancer risk in New Caledonia – a Pacific archipelago with some of the highest recorded thyroid cancer incidence rates in the world. Methods Food frequency questionnaire information from a population-based case-control study was used. Daily lignan and flavonoid intakes, expressed as aglycone equivalents, were estimated using Phenol-Explorer and relevant USDA databases. Unconditional logistic regression analyses were performed on data from 324 histologically confirmed cases of papillary or follicular carcinoma, diagnosed from 1993 to 1999, and 402 controls. Polyphenol intakes were analysed as both continuous and categorical variables (quartiles). Results Estimated median flavonoid and lignan intakes were 351.0 and 2.6 mg, respectively. When adjusting for sex, age, ethnic community, province of residence, BMI, smoking status, alcohol consumption and energy intake, no association with differentiated thyroid cancer risk was observed for flavonoids (OR = 1.06, 95% CI: 0.66, 1.70; comparing extreme quartiles), but a negative association was demonstrated for lignans (ORQ4vs.Q1=0.60, 95% CI: 0.37, 0.96; comparing extreme quartiles). Conclusions Our findings suggest that lignans may exert a protective effect on differentiated thyroid cancer. However, large-scale cohort studies and further analytical data on lignans are required to confirm this association. Key messages Lignans may play a role in thyroid carcinogenesis.

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