pH is a Neurally Regulated Physiological System. Increased Acidity Alters Protein Conformation and Cell Morphology and is a Significant Factor in the Onset of Diabetes and Other Common Pathologies

2012 ◽  
Vol 4 ◽  
pp. 8-12
Author(s):  
Graham Wilfred Ewing
Keyword(s):  
Cell Morphology ◽  
Protein Conformation ◽  
Physiological System ◽  
Onset Of Diabetes

Cell morphology, volume, and surface area determinations from multilevel contouring within HVEM micrographs of serial sections and whole-cell mounts

1987 ◽  
Vol 45 ◽  
pp. 588-589
Author(s):  
M. Marko ◽  
A. Leith ◽  
D. Parsons
Keyword(s):  
Surface Area ◽  
Electron Micrographs ◽  
Cell Morphology ◽  
Individual Variation ◽  
Serial Section ◽  
Stereo Pair ◽  
Complex Structures ◽  
Serial Sections ◽  
Surface Areas ◽  
Computer Based

The use of serial sections and computer-based 3-D reconstruction techniques affords an opportunity not only to visualize the shape and distribution of the structures being studied, but also to determine their volumes and surface areas. Up until now, this has been done using serial ultrathin sections.The serial-section approach differs from the stereo logical methods of Weibel in that it is based on the Information from a set of single, complete cells (or organelles) rather than on a random 2-dimensional sampling of a population of cells. Because of this, it can more easily provide absolute values of volume and surface area, especially for highly-complex structures. It also allows study of individual variation among the cells, and study of structures which occur only infrequently.We have developed a system for 3-D reconstruction of objects from stereo-pair electron micrographs of thick specimens.

Glycemia monitoring

1998 ◽  
Vol 2 ◽  
pp. 23-30
Author(s):  
Igor Basov ◽  
Donatas Švitra
Keyword(s):  
Diabetes Mellitus ◽  
Mathematical Model ◽  
Numerical Methods ◽  
Differential Equations ◽  
Blood Sugar ◽  
Self Regulation ◽  
Physiological System ◽  
Non Linear ◽  
The Mathematical Model

Here a system of two non-linear difference-differential equations, which is mathematical model of self-regulation of the sugar level in blood, is investigated. The analysis carried out by qualitative and numerical methods allows us to conclude that the mathematical model explains the functioning of the physiological system "insulin-blood sugar" in both normal and pathological cases, i.e. diabetes mellitus and hyperinsulinism.

Time course of the lymphopenia in BB rats. Relation to the onset of diabetes

Diabetes ◽  
1985 ◽  
Vol 34 (10) ◽  
pp. 955-959 ◽  
Author(s):  
J. F. Yale ◽  
M. Grose ◽  
E. B. Marliss
Keyword(s):  
Time Course ◽  
Bb Rats ◽  
Onset Of Diabetes
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