Glycemia monitoring

1998 ◽  
Vol 2 ◽  
pp. 23-30
Author(s):  
Igor Basov ◽  
Donatas Švitra

Here a system of two non-linear difference-differential equations, which is mathematical model of self-regulation of the sugar level in blood, is investigated. The analysis carried out by qualitative and numerical methods allows us to conclude that the mathematical model explains the functioning of the physiological system "insulin-blood sugar" in both normal and pathological cases, i.e. diabetes mellitus and hyperinsulinism.

2019 ◽  
Vol 23 (Suppl. 1) ◽  
pp. 1-12 ◽  
Author(s):  
Burhaneddin Izgi ◽  
Coskun Cetin

We develop Milstein-type versions of semi-implicit split-step methods for numerical solutions of non-linear stochastic differential equations with locally Lipschitz coefficients. Under a one-sided linear growth condition on the drift term, we obtain some moment estimates and discuss convergence properties of these numerical methods. We compare the performance of multiple methods, including the backward Milstein, tamed Milstein, and truncated Milstein procedures on non-linear stochastic differential equations including generalized stochastic Ginzburg-Landau equations. In particular, we discuss their empirical rates of convergence.


Author(s):  
Vladimir Grinkevich ◽  

The evaluation of the mathematical model parameters of a non-linear object with a transport delay is considered in this paper. A temperature controlled stage based on a Peltier element is an identification object in the paper. Several input signal implementations are applied to the input of the identification object. The least squares method is applied for the calculation of the non-linear differential equitation parameters which describe the identification object. The least squares method is used due to its simplicity and the possibility of identification non-linear objects. The parameters values obtained in the process of identification are provided. The plots of temperature changes in the temperature control system with a controller designed based on the mathematical model of the control object obtained as a result of identification are shown. It is found that the mathematical model obtained in the process of identification may be applied to design controllers for non-linear systems, in particular for a temperature stage based on a Peltier element, and for self-tuning controllers. However, the least square method proposed in the paper cannot estimate the transport delay time. Therefore it is required to evaluate the time delay by temperature transient processes. Dynamic object identification is applied when it is required to obtain a mathematical model structure and evaluate the parameters by an input and output control object signal. Also, identification is applied for auto tuning of controllers. A mathematical model of a control object is required to design the controller which is used to provide the required accuracy and stability of control systems. Peltier elements are applied to design low-power and small- size temperature stage . Hot benches based on a Peltier element can provide the desired temperature above and below ambient temperature.


Molecules ◽  
2020 ◽  
Vol 25 (11) ◽  
pp. 2694
Author(s):  
Amir Abbas ◽  
Muhammad Ashraf ◽  
Yu-Ming Chu ◽  
Saqib Zia ◽  
Ilyas Khan ◽  
...  

The main goal of the current work was to study the coupled mechanism of thermophoretic transportation and mixed convection flow around the surface of the sphere. To analyze the characteristics of heat and fluid flow in the presence of thermophoretic transportation, a mathematical model in terms of non-linear coupled partial differential equations obeying the laws of conservation was formulated. Moreover, the mathematical model of the proposed phenomena was approximated by implementing the finite difference scheme and boundary value problem of fourth order code BVP4C built-in scheme. The novelty point of this paper is that the primitive variable formulation is introduced to transform the system of partial differential equations into a primitive form to make the line of the algorithm smooth. Secondly, the term thermophoretic transportation in the mass equation is introduced in the mass equation and thus the effect of thermophoretic transportation can be calculated at different positions of the sphere. Basically, in this study, some favorite positions around the sphere were located, where the velocity field, temperature distribution, mass concentration, skin friction, and rate of heat transfer can be calculated simultaneously without any separation in flow around the surface of the sphere.


2008 ◽  
Vol 589 ◽  
pp. 335-340
Author(s):  
Zoltán Pálmai

We have developed a technological and mathematical model for the fast deformation of metals, which, as a result of the non-linear nature of the process, is equally suitable for the description of stable (continuous or periodic) and also chaotic states. In the case of stable solutions, the various numerical methods generally give consistent results, but in chaotic cases significant differences can be observed in the space of state characteristics, especially within the range determined by the strange attractor.


Author(s):  
Mahmoud Hamadiche

A non linear mathematical model addressing the passive mechanism of the cochlea is proposed in this work. In this respect, the interaction between the basilar membrane seen as an elastic solid and fluids in both scala vestibuli and tympani is developed. Via the fluid/solid interface, a full fluid/solid interaction is taking into account. Furthermore a significant improvement of the existing models has been made in both fluid flow modelling and solid modelling. In the present paper, the flow is three dimensional and the solid is non homogeneous two dimensional membrane where the material parameters depend only on the axial distance. The problem formulation leads to a system of non linear partial differential equations. Solution of the linearized system of partial differential equations of the proposed approach is presented. The numerical results obvious a lower and upper limits of the cochlea resonance frequency versus the material parameters of the basilar membrane. It is shown that a monochromatic acoustic wave energises only a portion of the basilar membrane and the location of the excited portion depends on the frequency of the incident acoustic wave. Those results explain the ability of the cochlea in deciphering the frequency of sound with high resolution in striking similarity with the known experimental results. The mathematical model shows that the excited strip of the basilar membrane by a monochromatic acoustic wave is very small when a transverse wave exists in the basilar membrane. Thus, a transverse wave improves highly the resolution of the cochlea in deciphering the high frequency of the incident acoustic wave.


2021 ◽  
Vol 24 (4) ◽  
pp. 17-24
Author(s):  
V.M. Churkin ◽  
T.Yu. Churkina ◽  
A.M. Girin

Mathematical modeling is created for the mathematical task of spatial motion of the controlled parachute-tether system of the “wind kite” type. The mathematical model parachute-tether system consists of a model of the main parachute and a model of the braking parachute. The parachutes are connected by the tether. The model of the main parachute is supposed to be the solid body. This solid body has two planes of symmetry. The braking parachute is the solid body with axial symmetry. The tether model is an absolutely flexible elastic thread. The tether is connected by ideal hinges with the main parachute and braking parachute. The control of the main parachute is carried out by changing the length of the control slings. Changing the length causes deformation of the dome. This is the reason for the change in its aerodynamics. Maneuvering of the main parachute occurs in the vertical plane, when the length of the control slings changes simultaneously. Maneuvering of the main parachute in space is carried out when the length of the control slings changes, when the slings are given a travel difference. The system of dynamic and kinematic equations is designed for calculating the controlled spatial movement of the main parachute, braking parachute and tether. The option exists when the mass of the tether and the forces applied to the tether cannot be neglected. The motion of the tether is represented by the equations of motion of an absolutely flexible elastic thread in projections on the axis of a natural trihedron. The mathematical model is represented by a system of ordinary differential equations and partial differential equations. The problem is solved using various numerical methods. The solution is possible with the help of an integrated numerical and analytical approach as well.


2021 ◽  
Vol 2092 (1) ◽  
pp. 012012
Author(s):  
O Krivorotko ◽  
D Andornaya

Abstract A sensitivity-based identifiability analysis of mathematical model for partial differential equations is carried out using an orthogonal method and an eigenvalue method. These methods are used to study the properties of the sensitivity matrix and the effects of changes in the model coefficients on the simulation results. Practical identifiability is investigated to determine whether the coefficients can be reconstructed with noisy experimental data. The analysis is performed using correlation matrix method with allowance for Gaussian noise in the measurements. The results of numerical calculations to obtain identifiable sets of parameters for the mathematical model arising in social networks are presented and discussed.


2020 ◽  
Vol 1 (27(54)) ◽  
pp. 4-7
Author(s):  
S.I. Kisil ◽  
T.S. Zaletova

Algorithms for predicting blood glucose based on the use of mathematical models that can be used in continuous monitoring systems for blood sugar are described.


2021 ◽  
Vol 114 ◽  
pp. 01020
Author(s):  
Arkadiy Plotnikov ◽  
Tatyana Goryacheva ◽  
Flyura Kazakova ◽  
Ekaterina Zakharchenko

This article is devoted to the further development of feedback loop models. They are used in the management of a single-industry firm. The development of the studying consists in the mathematical modeling of transients and assessing their impact on economic indicators. To solve this problem, the following was done in the article. A structural model of the functioning of a single-industry firm (SIF) is presented. It is built in accordance with the theory of automatic control (TAC) and includes elements: a management unit, a production unit, a sales unit, information nodes, as well as a feedback loop (FL). Equations and relationships describing the logic of the functioning of the company as a production system are presented. They allowed us to derive dynamic relationships and differential equations that reflect feedback loops on revenue and production costs. The system of expressions in operator form is presented, which describes the contour of the FL SIF. It has the form of a system of differential equations. It forms the basis of the mathematical model of SIF in the control system. This model made it possible to obtain a graphical interpretation of transients with closed and open FL based on the use of the Mathcad editor. Transients are fluctuations in sales volumes and production costs in the presence of disturbing influences. This is the scientific result and determines the novelty of the article.


Author(s):  
Aleksey Georgievich Borodkin ◽  
Elena Lvovna Gordeeva ◽  
Yuliya Lvovna Gordeeva ◽  
Yuriy Alekseevich Komissarov

The authors of the article produce the algorithm to evaluate the stability of the steady states for microbiological synthesis using mathematical models for kinetics based on the unstructured approach. The object under study is a continuous biotechnological process aiming to obtain a target product, in addition to biomass. The estimation of stability is performed using Hurwitz matrix. In this process the use of raw materials containing components for additional producing of the primary substrate are possible. The algorithm includes five steps: formulation of the mathematical model that takes into account biological and technological limits; definition of steady states (one or several) for which it is necessary to evaluate conditions of stability and to calculate process parameters for the adopted steady states resulted from solving a system of nonlinear algebraic equations of the mathematical model; formulation of the equations of the first approximation (the system of first-order linear differential equations with constant coefficients) and evaluation of the coefficients corresponding to the adopted steady states; formation of Hurwitz matrix and calculation of its items; calculation of necessary and sufficient conditions for stability using Hurwitz matrix. Two methods of calculating Hurwitz matrix have been shown. The first method is implemented by transforming the system of four differential equations of the first approximation into one fourth-order ordinary differential equation. In the course of transformation there were determined calculated ratios for coefficients of the matrix. In the second method the coefficients are calculated by solving vector equation for the system of first approximation with the introduction of eigen values. The algorithm has been used for evaluating steady states of microbiological synthesis for lactic acid production from raw materials containing the component reproducing the main substrate. The estimation has been carried out for two steady states, one of which is optimal. For numerical values of the constants (from the literature) both steady states were stable.


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